- Cardiac Arrhythmias and Treatments
- Atrial Fibrillation Management and Outcomes
- Cardiac electrophysiology and arrhythmias
- Cardiac pacing and defibrillation studies
- Cardiomyopathy and Myosin Studies
- Cardiac Ischemia and Reperfusion
- Congenital Heart Disease Studies
- Neurogenetic and Muscular Disorders Research
- COVID-19 Clinical Research Studies
- Nuclear Structure and Function
- RNA regulation and disease
- Long-Term Effects of COVID-19
- RNA Research and Splicing
- Congenital heart defects research
- Cardiac Arrest and Resuscitation
Westmead Hospital
2018-2021
The University of Sydney
2019-2021
Westmead Institute
2019-2021
The Royal Melbourne Hospital
2020
The University of Melbourne
2020
Minimal data exist on the Advisor HD Grid (HDG) catheter and Precision electroanatomic mapping (EAM) system for ventricular arrhythmia (VA) procedures. Using HDG catheter, EAM uses high-density (HD) wave best duplicate software to compare maximum peak-to-peak bipolar voltages within a small zone independent of wavefront direction orientation. This study aimed summarize procedural experience VAs using catheter.Clinical characteristics VA ablation procedures were retrospectively reviewed that...
Abstract Aims Major technological and procedural advancements have reinvigorated catheter ablation as adjunctive therapy for drug‐refractory ventricular tachycardia (VT). We examined temporal trends in VT ablations compared to other interventional cardiovascular procedures namely, percutaneous coronary intervention (PCI) atrial fibrillation (AF) Australia. Methods Results A retrospective review of numbers ablations, AF PCI was performed from 2008/09‐2016/17 the Australian Institute Health,...
Introduction Sheep have been adopted as a pre-clinical large animal for scientific research they are good models of cardiac anatomy and physiology, allow investigation pathophysiological processes which occur in the mammalian heart. There is, however, no defined model atrioventricular block sheep to assessment new treatment options. We therefore aimed develop an adult with focus on future novel applications. Methods results utilized six undergo two procedures each. The first procedure...
Key Teaching Points•LMNA cardiomyopathy is characterized by atrioventricular block, atrial arrhythmias, prothrombotic tendency, ventricular arrhythmias refractory to antiarrhythmic and catheter ablation therapy, progression end-stage heart failure, need for emergent cardiac transplantation.•Basal septal intramural substrate, capable of supporting multiple reentrant tachycardias, are typical, making challenging.•Fibrofatty replacement the myocardium characteristic nuclear changes on...
In ischemic cardiomyopathy, endocardial reentry has traditionally been the mechanistic paradigm for understanding ventricular tachycardia (VT).However, recognition is growing that epicardial myocardium a critical component VT substrate, even in patients with cardiomyopathy.In this report, we present novel case of three-dimensional involving components and an exit.
Background The basal septum is a common source of ventricular tachycardia (VT) in patients with structural heart disease (SHD).ObjectiveWe describe the clinical and electrophysiologic characteristics septal VTs SHD patients.MethodsData from 312 consecutive undergoing catheter ablation arrhythmias were reviewed.ResultsThirty-three basal-septal 31 (mean age 67.4{plus minus}14.2 years, left [LV] ejection fraction [EF] 42{plus minus}15%) identified. Patients LV breakthrough more likely to have...