Qian Yan

ORCID: 0000-0003-3914-9825
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Research Areas
  • Reproductive System and Pregnancy
  • Birth, Development, and Health
  • Cancer-related molecular mechanisms research
  • Pregnancy and preeclampsia studies
  • Cancer Risks and Factors
  • Gestational Diabetes Research and Management
  • Bioactive Compounds and Antitumor Agents
  • Ectopic Pregnancy Diagnosis and Management
  • Bioactive natural compounds
  • Circular RNAs in diseases
  • Preterm Birth and Chorioamnionitis
  • Pregnancy and Medication Impact
  • MicroRNA in disease regulation
  • Endometriosis Research and Treatment
  • Synthesis and bioactivity of alkaloids
  • Immune Response and Inflammation

Wenzhou Hospital of Traditional Chinese Medicine
2024

Yantaishan Hospital
2015-2020

Taishan Medical University
2015-2016

Abstract Endometrial cancer (EC) is deemed to be the most typical gynecologic malignant tumor. Despite incidence of EC being lower in Asia than that western countries, substantial increased has been observed past few decades Asia. Although various molecular testing methods and genomic science have developed, overall prognosis still disappointing. LncRNAs found influence progression cancers. CHL1‐AS1 upregulated ovarian endometriosis, nevertheless, mechanism biological function not explored....

10.1002/jcb.29486 article EN Journal of Cellular Biochemistry 2019-11-17

To observe the anti-tumor effect of matrine combined with cisplatin on U14 rat models cervical cancer.A total 80 female Kunming rats were used to establish cancer and then divided into groups I, II, III, IV, 20 in each. For Group control group, injection normal saline was given around tumors. 2 mg/kg 75 tumors while for IV same doses as Groups II III. The animals sacrificed 10 d after taken out comparisons tumor weights calculation rates, thymus spleen index index. Blood eyeball collected...

10.1016/j.apjtm.2015.11.005 article EN Asian Pacific Journal of Tropical Medicine 2015-11-13

To study the preventive and therapeutic effect of N-Acetyl-l-cysteine on infection-associated preterm labor in mice.A total 66 C57BL/6 inbred strain pregnant mice were selected randomly divided into groups A, B C, with 22 cases each group. Group C regarded as model group, prevention group treatment respectively. The was built by intraperitoneal injection Escherichia coli. Ten taken observed birth rates live rates, Three killed at 3 h, 6 12 h 24 after building model. Their uterus tissues...

10.1016/j.apjtm.2016.01.012 article EN Asian Pacific Journal of Tropical Medicine 2016-01-11

In the study, we investigated immune factors related to T helper 17 (Th17) cells and regulatory (Treg) in spontaneous abortion mice. The expression of Th17 was analyzed by interleukin (IL)-6, IL-17A secretion, RAR-related orphan receptor γt (RORγt) expression, proportion CD4 + IL-17 cells. levels IL-10, transforming growth factor β (TGF-β), Foxp3, Foxp3 were presented Treg expression. Higher embryo absorption rate found group than that normal pregnancy ( P < 0.01). Compared with mice,...

10.1177/2058739218760354 article EN cc-by-nc European Journal of Inflammation 2018-01-01

The aim of the present study was to investigate influence random urine albumin-creatinine ratio (ACR) pregnant women with hypertension during gestation period on perinatal outcome. A total 6,758 pregnancy-induced and proteinuria were randomly selected between September, 2009 June, 2015 for study. Kidney function, blood pressure, history gravidity parity, embryo number birth weight participants determined. Logistic regression paired data correlation analyses carried out kidney number, weight,...

10.3892/etm.2016.3620 article EN Experimental and Therapeutic Medicine 2016-08-25
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