A5101476461- Genomics and Phylogenetic Studies
- Microbial Community Ecology and Physiology
- Photosynthetic Processes and Mechanisms
- Transgenic Plants and Applications
- Protist diversity and phylogeny
- Methane Hydrates and Related Phenomena
- Plant biochemistry and biosynthesis
- Circular RNAs in diseases
- Plant tissue culture and regeneration
- Cancer-related molecular mechanisms research
- MicroRNA in disease regulation
- Nutrition, Genetics, and Disease
- Antioxidant Activity and Oxidative Stress
- Pregnancy and preeclampsia studies
- RNA modifications and cancer
- Diet and metabolism studies
- Mollusks and Parasites Studies
- Enhanced Recovery After Surgery
- Ginseng Biological Effects and Applications
- Glycosylation and Glycoproteins Research
- Peroxisome Proliferator-Activated Receptors
- Genomics, phytochemicals, and oxidative stress
- Immunotherapy and Immune Responses
- Hemodynamic Monitoring and Therapy
- Protein Interaction Studies and Fluorescence Analysis
Sun Yat-sen Memorial Hospital
2025
Sun Yat-sen University
2025
Shanghai University
2025
Affiliated Hospital of Shandong University of Traditional Chinese Medicine
2023-2024
Yantaishan Hospital
2019-2023
First Affiliated Hospital of Henan University
2023
Jiangxi Provincial Academy of Medical Sciences
2020
Nanchang University
2020
First Affiliated Hospital of Nanchang University
2020
Shandong Provincial QianFoShan Hospital
2017-2019
Metagenomics is expanding our knowledge of the gene content, functional significance, and genetic variability in natural microbial communities. Still, there exists limited information concerning regulation dynamics genes environment. We report here global analysis expressed a naturally occurring community. first adapted RNA amplification technologies to produce large amounts cDNA from small quantities total community RNA. The fidelity procedure was validated with Prochlorococcus cultures...
Marine dissolved organic matter (DOM) contains as much carbon the Earth's atmosphere, and represents a critical component of global cycle. To better define microbial processes activities associated with marine DOM cycling, we analyzed genomic transcriptional responses communities to high-molecular-weight (HMWDOM) addition. The cell density in unamended control remained constant, very few transcript categories exhibiting significant differences over time. In contrast, DOM-amended microcosm...
Summary Deep‐water nutrient injection in the North Pacific Subtropical Gyre provides an aperiodic yet significant source of inorganic nutrients to nutrient‐limiting surface waters, and has been implicated phytoplankton bloom formation. Here we examined short‐term transcriptional responses water picoplankton assemblages a deep‐sea (DSW) mixing experiment. Both flow cytometric transcriptomic analysis indicated stimulation Alteromonas ‐like population DSW‐amended treatment after 12 h, relative...
Lycopene ε-cyclase (ε-LCY) is a key enzyme that catalyzes the synthesis of α-branch carotenoids through cyclization lycopene. Two cDNA molecules encoding ε-LCY (designated Ntε-LCY1 and Ntε-LCY2) were cloned from Nicotiana tabacum. Ntε-LCY2 are encoded by two distinct genes with different evolutionary origins, one originating tobacco progenitor, sylvestris, other tomentosiformis. The coding regions 97% identical at nucleotide level 95% amino acid level. Transcripts Ntε-LCY detectable in both...
Carotenoids are important pigments in plants that play crucial roles plant growth and responses to environmental stress. Lycopene β cyclase (β-LCY) functions at the branch point of carotenoid biosynthesis pathway, catalyzing cyclization lycopene. Here, a β-LCY gene from Nicotiana tabacum, designated as Ntβ-LCY1, was cloned functionally characterized. Robust expression Ntβ-LCY1 found leaves, obviously induced by salt, drought, exogenous abscisic acid treatments. Strong accumulation...
Summary To investigate the temporal, spatial and phylogenetic resolution of marine microbial community structure variability, we designed expanded a genome proxy array (an oligonucleotide microarray targeting fragments genomes), evaluated it against metagenomic sequencing, applied to time‐series samples from Monterey Bay. The targeted 268 genotypes across much known diversity cultured uncultured microbes. target abundances measured by were highly correlated pyrosequence‐based (linear...
Goals To assess the efficacy and safety of Chinese Medicine Prescription “W-LHIT” in subjects with simple obesity, to explore its potential mechanism action. Methods Thirty-seven patients aged 18 60 from Wei-En hospital (Weifang City, Shandong, China), participated a double blinded, placebo-controlled study. Subjects were randomly divided into 2 groups, treatment 19 placebo group. The group took capsules for two months, while control received capsules. Both groups accepted healthy lifestyle...
Abstract Background Mental health issues in preschool children are a significant public concern with long-term developmental implications. Understanding how reallocations of time among different 24-hour movement behaviors-moderate-to-vigorous physical activity (MVPA), light (LPA), sedentary behavior (SED), and sleep (SLP)-affect various dimensions mental is essential for designing effective interventions. Methods In this cross-sectional study, 828 Chinese aged 3 to 6 years were assessed....
Abstract Endometrial cancer (EC) is deemed to be the most typical gynecologic malignant tumor. Despite incidence of EC being lower in Asia than that western countries, substantial increased has been observed past few decades Asia. Although various molecular testing methods and genomic science have developed, overall prognosis still disappointing. LncRNAs found influence progression cancers. CHL1‐AS1 upregulated ovarian endometriosis, nevertheless, mechanism biological function not explored....
The mitochondrial genome (mitogenome) can provide information for phylogenetic analyses and evolutionary biology. We first sequenced, annotated, characterized the mitogenome of Philomycus bilineatus in this study. complete was 14,347 bp length, containing 13 protein-coding genes (PCGs), 23 transfer RNA genes, two ribosomal non-coding regions (A + T-rich region). There were 15 overlap locations 18 intergenic spacer found throughout P. bilineatus. A T content 72.11%. All PCGs used a standard...
Ischemic diseases, including coronary heart disease and peripheral arterial obstructive disease, pose significant health threats worldwide. Angiogenic therapy has emerged as a comprehensive approach to combat these diseases. In recent years, traditional Chinese medicine attracted increased attention due its demonstrable therapeutic effects on ischemic Panax ginseng, perennial herb from the genus of Araliaceae family, is widely employed in clinical treatment conditions. Previous research...
Real-time quantitative reverse transcription-PCR (qRT-PCR) is an undeniably effective tool for measuring levels of gene expression, but the accuracy and reliability statistical data obtained depend mainly on basal expression selected housekeeping genes in many samples. To date, there have been few analyses stable Onchidium reevesii under salinity stress injury. In this study, stabilities seven commonly used genes, CYC , RPL28S ACTB TUBB EF1a Ubiq 18S RNA were investigated using BestKeeper,...
To provide the hard-won information on HIV-1 polymorphism from inmates in prison and to study genetic variation of strains, we analyzed characterization nucleotide corresponding protein sequences naturally occurring nef derived 16 HIV-1-positive prisons China. Nested PCR DNA sequencing were used determine peripheral blood mononuclear cells. Phylogenetic analysis revealed a distribution viral among subtype B, CRF_BC, CRF_AE, with B accounting for more than half genotypes. When compared...
Cardiovascular diseases (CVDs) remain a key contributor to global morbidity and mortality. Being vital regulator of hypoxia, hypoxia-inducible factor-1α (HIF-1α) is crucial player in CVD treatment. Recently, increasing attention has been paid the effect natural drugs on CVDs. According some studies, HIF-1α potential target for treatment traditional Chinese medicine. In this study, we describe mechanism underlying regulatory role CVDs summarize 30 3 formulations through its signaling pathway....