- Osteoarthritis Treatment and Mechanisms
- Rheumatoid Arthritis Research and Therapies
- Hip disorders and treatments
- Autoimmune and Inflammatory Disorders Research
- Healthcare Policy and Management
- Chronic Disease Management Strategies
- Total Knee Arthroplasty Outcomes
- Primary Care and Health Outcomes
- Diabetes Management and Education
- Health Systems, Economic Evaluations, Quality of Life
- Fibromyalgia and Chronic Fatigue Syndrome Research
- Systemic Lupus Erythematosus Research
- Musculoskeletal Disorders and Rehabilitation
- Lower Extremity Biomechanics and Pathologies
- Spondyloarthritis Studies and Treatments
- Musculoskeletal pain and rehabilitation
- Knee injuries and reconstruction techniques
- Global Health Care Issues
- Adolescent and Pediatric Healthcare
- Bone and Joint Diseases
- Healthcare cost, quality, practices
- Physical Activity and Health
- Mental Health Treatment and Access
- Systemic Sclerosis and Related Diseases
- Shoulder Injury and Treatment
Cork University Hospital
2024
MRC Clinical Trials Unit at UCL
2024
University College London
2024
Optum (United States)
2021-2023
Centers for Disease Control and Prevention
2013-2022
King's Inns
2022
National Center for Chronic Disease Prevention and Health Promotion
2014-2021
Ollscoil na Gaillimhe – University of Galway
2021
CDC Foundation
2005-2020
Office of Science
2019-2020
Prescription opioid-related overdose deaths increased sharply during 1999-2010 in the United States parallel with opioid prescribing. CDC assessed changes national-level and county-level prescribing 2006-2015.CDC analyzed retail prescription data from QuintilesIMS to assess 2006 2015, including rates, amounts, dosages, durations prescribed. examined patterns 2010 2015.The amount of opioids prescribed peaked at 782 morphine milligram equivalents (MME) per capita then decreased 640 MME 2015....
To estimate the lifetime risk of symptomatic knee osteoarthritis (OA), overall and stratified by sex, race, education, history injury, body mass index (BMI).The OA in at least 1 was estimated from logistic regression models with generalized estimating equations among 3,068 participants Johnston County Osteoarthritis Project, a longitudinal study black white women men age >or=45 years living rural North Carolina. Radiographic, sociodemographic, data measured baseline (1990-1997) first...
Objective Provide a contemporary estimate of osteoarthritis (OA) by comparing the accuracy and prevalence alternative definitions OA. Methods The Medical Expenditure Panel Survey (MEPS) household component (HC) records respondent‐reported medical conditions as open‐ended responses; professional coders translate these responses into International Classification Diseases, Ninth Revision, Clinical Modification (ICD‐9‐CM) codes for files. Using other data from MEPS‐HC files, we constructed 3...
We estimated the economic impact of arthritis using 2013 US Medical Expenditure Panel Survey (MEPS) data.We calculated arthritis-attributable and all-cause medical expenditures for adults age ≥18 years earnings losses among those ages 18-64 who had ever worked. costs multistage regression-based methods, conducted sensitivity analyses to estimate 2 other definitions in MEPS.In 2013, total national were $139.8 billion (range $135.9-$157.5 billion). Across expenditure categories, ambulatory...
Abstract Objective To obtain estimates of medical care expenditures and earnings losses associated with arthritis other rheumatic conditions the increment in such costs attributable to US 2003, compare these those from 1997. Methods Estimates for 2003 were derived Medical Expenditures Panel Survey (MEPS), a national probability sample households. We tabulated adult MEPS respondents, stratified by comorbidity status, used regression techniques estimate conditions. also estimated sustained...
OVERVIEW: Arthritis, of which osteoarthritis (OA) is the most common type, frequent cause disability among adults in United States. The authors reviewed epidemiologic literature to identify studies that describe population-based burden OA—that is, all community. They found 27 million adults—more than 10% U.S. adult population—had clinical OA 2005, and 2009 was fourth hospitalization. leading indication for joint replacement surgery; 905,000 knee hip replacements were performed at a cost...
There has been limited characterization of the burden anxiety and depression, especially former, among US adults with arthritis in general population. The study objective was to estimate prevalence correlates depression doctor-diagnosed arthritis.The sample comprised ages ≥ 45 years (n = 1,793) from Arthritis Conditions Health Effects Survey (a cross-sectional, population-based, random-digit-dialed telephone interview survey). Anxiety were measured using separate validated subscales Impact...
Objective The California Lupus Surveillance Project ( CLSP ) is a population‐based registry of individuals with systemic lupus erythematosus SLE residing in San Francisco County, from 2007 to 2009, special focus on Asian/Pacific Islander and Hispanic patients. We used retrospective data analyze racial ethnic differences manifestations the timing risk developing severe manifestations. Methods A total 724 patients were retrospectively identified. Prevalence ratios PR s) calculated using...
Objective Symptomatic hand osteoarthritis (OA) is a common condition that affects strength and function, causes disability in activities of daily living. Prior studies have estimated the lifetime risk symptomatic knee OA 45% hip 25%. The objective present study was to estimate overall OA, stratified according potential factors. Methods Data were obtained from 2,218 adult subjects (ages ≥45 years) Johnston County Osteoarthritis Project, population‐based prospective cohort among residents...
Arthritis has been the most frequently reported main cause of disability among U.S. adults for >15 years (1), was responsible >$300 billion in arthritis-attributable direct and indirect annual costs during 2013 (2), is linked to disproportionately high levels anxiety depression (3), projected increase 49% prevalence from 2010-2012 2040 (4). To update national estimates arthritis activity limitation (AAAL) adults, CDC analyzed combined National Health Interview Survey (NHIS) data 2016-2018....
Abstract Objective To estimate the national prevalence of arthritis‐attributable work limitation (AAWL) among persons ages 18–64 with doctor‐diagnosed arthritis and examine correlates AAWL. Methods Using 2002 National Health Interview Survey, we estimated AAWL (limited in whether individuals work, type they do, or amount do) univariable multivariable‐adjusted logistic regression analyses. Survey data were analyzed SAS SUDAAN to account for complex sample design. Results A total 5.3% all US...
Objective To determine the risk of all‐cause and disease‐specific mortality among older women with hip osteoarthritis (OA) to identify mediators in causal pathway. Methods Data were from Study Osteoporotic Fractures, a US population‐based cohort study 9,704 white age ≥65 years. The analytic sample included radiographs at baseline (n = 7,889) year 8 5,749). Mortality was confirmed through October 2013 by death certificates hospital discharge summaries. Radiographic OA (RHOA) defined as Croft...
In the United States, arthritis is a leading cause of disability (1,2); affected an estimated 52.5 million (22.7%) adults in 2010-2012 and has been projected to affect 78.4 by 2040 (3). Severe joint pain (SJP) can limit function seriously compromise quality life (4,5). To determine prevalence SJP among with doctor-diagnosed arthritis, trend from 2002 2014, CDC analyzed data National Health Interview Survey. approximately one fourth had (27.2%). Within selected groups, age-standardized was...
To examine arthritis impact among US adults with self-reported doctor-diagnosed using the International Classification of Functioning, Disability and Health (ICF) framework (including impairments, activity limitations, environmental, personal factors domains social participation restriction [SPR] as outcome) overall those without SPR, to identify correlates SPR.Cross-sectional 2009 National Interview Survey data were analyzed distribution ICF domain components. Unadjusted...
An estimated 54.4 million (22.7%) U.S. adults have doctor-diagnosed arthritis (1). A report in 2012 found that, among aged ≥45 years with arthritis, approximately one third reported having anxiety or depression, more common than depression (2). Studies examining mental health conditions focused largely on subtypes, and middle-aged older adults, not been nationally representative (3). To address these knowledge gaps, CDC analyzed 2015-2017 National Health Interview Survey (NHIS) data* to...
Rural populations in the United States have well documented health disparities, including higher prevalences of chronic conditions (1,2). Doctor-diagnosed arthritis is one most prevalent (22.7%) States, affecting approximately 54.4 million adults (3). The impact considerable: an estimated 23.7 arthritis-attributable activity limitation (AAAL). age-standardized prevalence AAAL increased nearly 20% from 2002 to 2015 Arthritis varies widely by state (range = 19%-36%) and county 16%-39%) (4)....
Abstract Objective To provide estimates of the total medical care expenditures and earnings losses associated with arthritis other rheumatic conditions (AORC), as well increment in such costs specifically attributable to these conditions, US 1997. Methods The were derived from 1997 Medical Expenditures Panel Survey (MEPS), a national probability sample 14,147 households including 34,551 persons, whom 4,776 self‐reported arthritis. After weighting, those who AORC represent 38.4 million...