A5089217875- Dialysis and Renal Disease Management
- Renal Diseases and Glomerulopathies
- Systemic Lupus Erythematosus Research
- Heart Failure Treatment and Management
- Amyloidosis: Diagnosis, Treatment, Outcomes
- Acute Kidney Injury Research
- Renal and Vascular Pathologies
- Chronic Kidney Disease and Diabetes
- Rheumatoid Arthritis Research and Therapies
- Central Venous Catheters and Hemodialysis
- Mechanical Circulatory Support Devices
- Electrolyte and hormonal disorders
- Vasculitis and related conditions
- Streptococcal Infections and Treatments
- Potassium and Related Disorders
- Neurological and metabolic disorders
- IgG4-Related and Inflammatory Diseases
- Pediatric Urology and Nephrology Studies
- Kidney Stones and Urolithiasis Treatments
- Ocular Oncology and Treatments
- Complement system in diseases
- Multiple Myeloma Research and Treatments
- Ocular Disorders and Treatments
- Sarcoidosis and Beryllium Toxicity Research
- Restless Legs Syndrome Research
University of Kansas
2022-2025
University of Kansas Medical Center
2022-2024
Queen's University
2023
University of Pittsburgh
2011-2022
University Medical Center
2022
UPMC Presbyterian
2014
Presbyterian Hospital
2014
Hôpital du Sacré-Cœur de Montréal
2010
Imperial College London
2010
Louisiana State University Health Sciences Center Shreveport
2010
<b><i>Background:</i></b> Fatigue is an important symptom to patients with advanced chronic kidney disease (CKD). The aim of this study examine the prevalence and severity fatigue among non-dialysis-dependent CKD end-stage renal (ESRD) patients, association subjective objective sleep quality, identify other modifiable factors associated fatigue. <b><i>Methods:</i></b> A cross-sectional survey 87 (eGFR ≤45 ml/min/1.73 m<sup>2</sup>)...
Observational evidence has suggested that RRT modality may affect recovery after AKI. It is unclear whether initial choice of intermittent hemodialysis or continuous affects renal recovery, survival, development ESRD in critically ill patients when made primarily on hemodynamics.We performed a retrospective cohort study examining adults (≥18 years old) admitted to intensive care units from 2000 2008 who received for AKI and survived hospital discharge 90 days. We analyzed (alive not...
Abstract Objective To investigate the incidence of noncardiac vascular disease in patients with rheumatoid arthritis (RA) and its relationship to systemic extraarticular a community‐based cohort. Methods A retrospective medical record review 609 incident RA diagnosed during 1955–1994 was carried out Olmsted County, Minnesota. Patients were followed up from 1955 2000 (median followup 11.8 years). Incident severe manifestations (including pericarditis, pleuritis, vasculitis) recorded according...
Complement activation plays a key role in the pathogenesis of lupus nephritis (LN), severe complication systemic erythematosus (SLE). We prospectively evaluated 15 LN subjects and two control groups: 13 non-SLE renal (control A) 239 SLE without B). All had C4d levels on circulating erythrocytes (E-C4d), reticulocytes (R-C4d) platelets (P-C4d) measured by flow cytometry, while deposition tissue was semiquantitatively assessed A using immunoperoxidase staining. Compared with A, biopsies higher...
Assessment of adequacy intermittent hemodialysis (IHD) is conventionally based upon urea kinetic models for calculation single pool Kt/Vurea (Kt/V), with 1.2 accepted as minimum adequate clearance thrice weekly IHD. In the Acute Renal Failure Trial Network (ATN) Study, IHD in patients acute kidney injury (AKI) was assessed using Kt/V. However, equations Kt/V require volume distribution urea, which highly variable AKI. Therefore, simpler methods are needed to assess We correlation reduction...
Objective The objective is to provide evidence‐based and expert guidance for the screening, treatment, management of lupus nephritis. Methods Core Team developed clinical questions nephritis using PICO format (population, intervention, comparator, outcome). Systematic literature reviews were completed each question, Grading Recommendations Assessment, Development Evaluation (GRADE) methodology was used assess quality evidence formulate recommendations. Voting Panel achieved a consensus ≥70%...
Objective The objective is to provide evidence‐based and expert guidance for the screening, treatment, management of lupus nephritis. Methods Core Team developed clinical questions nephritis using PICO format (population, intervention, comparator, outcome). Systematic literature reviews were completed each question, Grading Recommendations Assessment, Development Evaluation (GRADE) methodology was used assess quality evidence formulate recommendations. Voting Panel achieved a consensus ≥70%...
Fournier's gangrene is characterized as an aggressive necrotizing process caused by a polymicrobial infection that includes virulent organisms. We report the first case of low-virulence organism, Lactobacillus gasseri.
In patients with end-stage renal disease, peripheral vascular disease (PVD) is prevalent. We assessed the extent to which severity of PVD predicts mortality, hospitalizations and health-related quality life (HRQOL) in hemodialysis (HD) enrolled Hemodialysis (HEMO) Study. performed a subanalysis HEMO Study, randomized controlled trial. Adjusted predictors were analyzed through multivariable stepwise ordinal logistic model. Relationships between mortality determined Cox proportional hazards...
This is a case of IgG4-related systemic disease (ISD) and its rare renal manifestation as membranous nephropathy (MGN). The patient presented with peripheral edema, hematuria proteinuria. 24-h urine revealed proteinuria up to 15 g/d. Renal biopsy MGN many IgG4-positive plasma cells. Serum IgG4 levels were elevated at 750 mg/dl (9 - 89 mg/d). Biopsies multiple tissues Prednisone was initiated after making the diagnosis ISD. However, progressed into failure eventually needed dialysis despite...
We report on an otherwise healthy 47-year-old male who developed subacute tenosynovitis of the hand associated with night sweats and inguinal lymphadenopathy. He had a past history granulomatous mediastinal lymphadenitis positive histoplasmosis serology 11 years previously. Carpal tunnel exploration biopsy demonstrated inflammation. Granulomatous inflammation, hypercalcemia, elevated serum angiotensin converting enzyme (ACE) level suggested diagnosis sarcoidosis, however infection could...
Background. Chronic kidney disease (CKD) is common in heart failure (HF) and associated with poor outcomes. Renal replacement therapy (RRT) may be deferred over concerns regarding tolerability outcomes HF. Our objectives were to ascertain the incidence of RRT, changes RRT time association between survival hospitalized HF patients.
Pregnancy-related renal diseases are unique and need special attention, both for diagnosis management. The major confounding factors the physiological multiorgan changes that occur throughout gestational period. Proper of disease is also important, given impact varied management options on maternal fetal health. A young middle-aged female with a long-standing history diabetes presented to hospital worsening proteinuria in her second trimester pregnancy. Clinical history, examinations,...
Poster: Glomerular Diseases: Clinical Features and Outcomes in Nephrotic Syndromes Complement-Mediated Diseases
Primary membranous nephropathy (MN) is due to autoantibodies phospholipase A2 receptor (PLA2R Ab). It unclear whether COVID-19 vaccines can trigger flares of glomerular diseases such as primary MN. There have been increasing reports presenting or flaring after receipt vaccines. We present a patient with MN who developed nephrotic syndrome receiving her second mRNA-1273 vaccine positive PLA2R Ab. Renal biopsy confirmed She was treated for flare rituximab in manner similar...