Abstract Summary: Rapid advances in pharmaceutical sciences have brought ever-increasing interests combined therapies for better clinical efficacy and safety, especially cases of complicated refractory diseases. Innovative experimental technologies theoretical frameworks are being actively developed multicomponent drug research. In this work, we present the Drug Combination Database, with aims to facilitate analyses known combinations, summarize patterns beneficial interactions, provide a...

Several reputation systems have been proposed for mobile ad-hoc networks in order to stimulate cooperation among nodes. However, whether or not the nodes will agree on of other is studied. In this paper, we present a formal specification and analysis general class mechanisms locally update Given an initial assessment nodes, formally show that under mild conditions, achieve agreement. Our captures propagation using graph connectivity makes use recent theoretical result [A. Jadbabaie, et. al.,...

Abstract In the information age, rapid development of technology and has created a good learning environment for each student, so that everyone can grow actively vividly, which is main theme today’s age. This paper aimed to explore application research intelligent multi-sensor in higher education teaching system. this paper, fusion algorithm was proposed, effect system based on studied analyzed. The experimental results be obtained through SPSS (Statistical Product Service Solutions) data...

An integrated approach that considers the performance limitations of tracking control systems for air-breathing hypersonic vehicles is proposed. First, a set ascent trajectories obtained as candidates through trajectory design method available acceleration. Second, basic theory limitations, which adopted to calculate limits on trajectory, integrated. The open-loop dynamics responsible these system. Comprehensive specifications stability, accuracy, and robustness are derived, flight envelope...

The single HST (Hydro Static Transmission) mechanical differential transmission gearbox of crawler combine harvester is subjected to the impact alternating loads in field operation, resulting its fatigue failure. traditional durability test can improve fault-free working time machinery, but it not suitable for agricultural machinery with time-varying load frequency bandwidth and stress amplitude. Therefore, this paper, a fault diagnosis method based on order analysis was proposed considering...

In this article we investigate a model of route selection for interdomain traffic engineering where routing to multiple destinations can be coordinated. We identify potential instability and inefficiency problems, derive set practical guidelines guarantee stability without global coordination. Using realistic Internet topology, show that oscillations happen even when small number ASes coordinate just if the coordination does not follow our guidelines. Wc further extend so adopt any...

Grid computing supports shared access to resources from cooperating organizations or institutes in the form of virtual organizations. Resource brokering middleware, commonly known as a meta-scheduler resource broker, matches jobs distributed resources. Recent advances meta- scheduling capabilities are extended enable matching across multiple Several architectures have been proposed for interoperating meta-scheduling systems. This paper presents hybrid approach, combining hierarchical and...

Associations between pathogens and hypertension (HT) has been reported, but few studies have focused on the relationship aggregate HT. The present study explored whether risk of HT is associated with each pathogen (defined as Chlamydia pneumoniae (C. pneumoniaee), mycoplasma (m. pneumoniae), helicobacter pylori (h. pylori) coxsackie virus) or in chinese mongolians.One thousand thirty Chinese Mongolians aged 30 years more were recruited, including 488 hypertensive 942 normotensive subjects....

Big data poses challenges to the technologies required process of high volume, velocity, variety, and veracity. Among challenges, storage computing by big analytics is usually huge, as a result capabilities are often provisioned in cloud delivered form Web-based services. Solid-state drive (SSD) widely used nowadays an elementary hardware feature infrastructure for For example, Amazon Web Service (AWS) offers EC2 instances with SSD storage, its key-value store, DynamoDB, backed up superior...

This study investigates the optimal design problems for hypersonic morphing vehicle. The correlations among shock wave variation, propulsive performance, and control effect are discussed. inversion methods applied to calculate aerodynamic forces moments of vehicle based on theories computational mechanics. Then, model is built, performance indexes reflecting waverider flight characteristics considering appropriate conditions initial parameters presented. Furthermore, variable metric...

For aerospace vehicles with uncertainty, strong nonlinearity, and high-performance requirements, the model predictive control (MPC) method has attracted many researchers' attention its unique advantages. Although this a good effect, it is computationally expensive, especially for nonlinear MPC. In addition, cannot guarantee stability performance requirements limited flexibility in dealing large initial errors. To overcome these limitations, article implemented to obtain scheme that can...

Abstract Bone formation is dependent on the osteoblasts which are differentiated from bone marrow stromal cells (BMSCs). In addition to potent proliferation, self‐renewal, and pluripotent differentiation, BMSCs have been extensively studied due their low immunogenicity immunomodulatory effects. Recently, galectin‐1 (Gal‐1) has proposed as a mediator of properties BMSCs. Previous study demonstrated that Gal‐1 showed age‐related decline in mice serum was positively associated with mass mice....

Powerful actuators are both indispensable and critical components for the flight control system of hypersonic vehicles. More importantly, performance has substantial impact on ability; therefore, when designing system, one needs to fully take into account actuator restraints in order meet efficient precise demands under complex conditions. In this article, advanced methods concerned with limitations discussed First, longitudinal model vehicle is established consideration nonlinear coupling...

With the development of high-performance aircraft, precise air data are necessary to complete challenging tasks such as flight maneuvering with large angles attack and high speed. As a result, flush sensing system (FADS) was developed satisfy stricter control demands. In this paper, comparative stuides on solving model algorithm for FADS conducted. First, basic principles given elucidate nonlinear relations between inputs outputs. Then, several different models algorithms provided compute...

The study of digital Chinese calligraphy has become more valuable nowadays. While existing researches on analysis are primarily focused stroke-based character recognition and simulation, we propose a global feature descriptor to deal with style problem in this paper. proposed method extracts three categories features: position features, proportion features projection features. These then used train an SVM classifier style. We test the based five-style set. experimental results show that can...

The emphasis of this paper lies in the development an efficient approach to reproduce behaviors scramjet-powered hypersonic system with high fidelity. modeling dual-mode scramjet powered vehicle dynamics shock interaction, Ram-to-Scram transition, and finite rate chemistry reaction is firstly introduced. structure surrogate model identified implement iterative fractional factorial design (IFFD). In order declare reliability models, ν-gap metric applied distinguish difference among these...

In this study, a novel type of swarm intelligence algorithm referred as the anas platyrhynchos optimizer is proposed by simulating cluster action platyrhynchos. Starting from core algorithm, on premise use few parameters and ease in implementation, mathematical model flow are given, balance between global search local development ensured. The was applied to benchmark function cooperative path planning solution for multi-UAVs means testing performance algorithm. optimization results showed...