A5103158235- Organic Chemistry Cycloaddition Reactions
- Synthesis and Reactions of Organic Compounds
- Crystallization and Solubility Studies
- X-ray Diffraction in Crystallography
- Synthesis and Reactivity of Sulfur-Containing Compounds
- Fluorine in Organic Chemistry
- Synthesis and Biological Evaluation
- Synthesis of heterocyclic compounds
- Chemical Reaction Mechanisms
- Synthesis and Characterization of Heterocyclic Compounds
- Synthesis and Characterization of Pyrroles
- Chemical synthesis and pharmacological studies
- Conducting polymers and applications
- Organic Electronics and Photovoltaics
- Synthesis and biological activity
- Chemical Reactions and Mechanisms
- Synthesis and Reactivity of Heterocycles
- Porphyrin and Phthalocyanine Chemistry
- Molecular Junctions and Nanostructures
- Chemical Synthesis and Reactions
- Chemical Synthesis and Analysis
- Photochemistry and Electron Transfer Studies
- Structural and Chemical Analysis of Organic and Inorganic Compounds
- Synthesis of Organic Compounds
- Sulfur-Based Synthesis Techniques
Slovak University of Technology in Bratislava
2014-2024
Institute of Organic Chemistry
2021-2023
Polymer Institute of the Slovak Academy of Sciences
2016
Wrocław University of Science and Technology
2001
Université Le Havre Normandie
1994
Institute of Chemical Technology
1985
Université Paris-Sud
1984
Université Paris Cité
1984
Donetsk State University of Management
1978
Chemistry of 2-aminothiophenes is arguably one the most extensive and dynamic field present-day thiophene research.Since 1961 when first report on Gewald reaction was reported it became a universal method for synthesis substituted has gained prominence in recent times.The availability reagents mild conditions all contribute to versatility this reaction.This review summarizes synthetic strategies 2-aminothiophenes.Consequently, details about proposed mechanism Gewald-like reactions wide scope...
The increasing occurrence of pharmaceuticals in wastewater poses environmental and health risks. This study focuses on developing evaluating cost-effective carbon sorbents, specifically biochar graphitic nitride, for efficiently removing pharmaceutical contaminants from 2023 samples a treatment plant serving around 300,000 people. adsorptive capabilities these materials were evaluated using liquid chromatography-tandem mass spectrometry (LC-MS/MS) the quantification their metabolites....
The development of copper(II) thiosemicarbazone complexes as potential anticancer agents, possessing dual functionality inhibitors R2 ribonucleotide reductase (RNR) and tubulin polymerization by binding at the colchicine site, presents a promising avenue for enhancing therapeutic effectiveness. Herein, we describe syntheses physicochemical characterization four isomeric proligands
Raman modes of the new processable polymer poly(2,3-alkyl-thieno[3,4-b]-pyrazine) with a bandgap about 0.9 eV were measured and calculated. spectroscopy revealed two strong lines at 1520 cm−1 1560 in CC stretching mode region. By changing exciting laser line these exhibit dispersion 16 25 cm−1/eV, respectively. Calculations on ground state that quinonoid structure is by 13 kcal/mol per repeat unit more stable than aromatic form. using scaled quantum mechanical oligomer force field method we...
Reactions of 5-tert-butyl-2-hydroxy-3-methylsulfanylbenzaldehyde S-methylisothiosemicarbazone and 5-tert-butyl-2-hydroxy-3-phenylsulfanylbenzaldehyde with pentane-2,4-dione (Hacac) triethyl orthoformate in the presence M(acac)2 as template source at 107 °C afforded metal complexes type MIIL1 MIIL2, where M = Ni Cu, a new Schiff base ligand thiomethyl (H2L1) and/or thiophenyl (H2L2) group ortho position phenolic moiety. Demetalation NiL1 CHCl3 HCl(g) H2L1. The latter reacts Zn(OAc)2·2H2O...
Thiosemicarbazones continue to attract the interest of researchers as potential anticancer drugs. For example, 3-aminopyridine-2-carboxaldehyde thiosemicarbazone, or triapine, is most well-known representative this class compounds that has entered multiple phase I and II clinical trials. Two new triapine derivatives HL1 HL2 were prepared by condensation reactions 2-pyridinamidrazone S-methylisothiosemicarbazidium chloride with 3-N-(tert-butyloxycarbonyl) amino-pyridine-2-carboxaldehyde,...
Abstract A laboratory, multigram (1000 g in an hour) preparation procedure for 2,3-dimethylfuran, based on the frequently repeated thermal cyclization of (Z) 3-methyl-2-penten-4-yn-1-ol, as well its subsequent formylation, acetylation and oxidation is described.
4-Chlor-3-coumarincarbaldehyde 2 or 4-azido-3-coumarincarbaldehyde 3 are converted into 1,4benzodiazepines 9-12 by nucleophilic substitution with diamines 4-7 and subsequent cyclization good yields.Following the same methodologies, carbaldehydes when treated 2-aminophenol 8 afforded 4-(2'-hydroxyphenyl)-amino-3-coumarincarbaldehyde 13 in yields.