A5051479591- Infrastructure Maintenance and Monitoring
- Corneal surgery and disorders
- Asphalt Pavement Performance Evaluation
- Glaucoma and retinal disorders
- Intraocular Surgery and Lenses
- Ophthalmology and Visual Impairment Studies
- Protein Hydrolysis and Bioactive Peptides
- Proteins in Food Systems
- Computational Drug Discovery Methods
- Enzyme Catalysis and Immobilization
- Concrete Properties and Behavior
- Concrete Corrosion and Durability
- Non-Destructive Testing Techniques
- Phytochemicals and Antioxidant Activities
- Optical measurement and interference techniques
- Biochemical effects in animals
- Geophysical Methods and Applications
- Retinal Diseases and Treatments
- Bee Products Chemical Analysis
- Cerebral Venous Sinus Thrombosis
- Seismic Waves and Analysis
- Microencapsulation and Drying Processes
- Neurosurgical Procedures and Complications
- Material Properties and Failure Mechanisms
- Natural Antidiabetic Agents Studies
Beijing Technology and Business University
2022-2025
University of Illinois Urbana-Champaign
2018-2025
Affiliated Eye Hospital of Wenzhou Medical College
2020-2024
Wenzhou Medical University
2020-2024
University of Illinois at Springfield
2023
Zhejiang University
2023
National Clinical Research Center for Digestive Diseases
2020-2023
Arizona State University
2023
First Affiliated Hospital of Kunming Medical University
2023
Kunming Medical University
2023
The conventional surface reflection method has been widely used to measure the asphalt pavement layer dielectric constant using ground-penetrating radar (GPR). This may be inaccurate for in-service thickness estimation with variation through depth, which could addressed extended common mid-point (XCMP) air-coupled GPR antennas. However, factors affecting XCMP on prediction accuracy haven't studied. Manual acquisition of key is required, hinders its real-time applications. study investigates...
PurposeTo evaluate the predictive accuracy of modern intraocular lens (IOL) formulas and axial length (AL) adjusted traditional IOL formulas, including Wang-Koch Cooke-modified AL (CMAL) method, in long eyes with plate-haptic IOLs, to compare refractive prediction error variances C-loop IOLs.DesignRetrospective consecutive case series study.MethodsData from 391 Zeiss 509M 302 Alcon SN6CWS implants highly myopic patients, following cataract surgery January 2019 November 2023, were collected....
This study aimed to screen out antibacterial peptides derived from sesame (Sesamum indicum L.) through in silico and vitro methods. In proteolysis of proteins with pepsin, trypsin, chymotrypsin was performed the online server BIOPEP-UWM. The CAMPR3 used predict antimicrobial effect peptides. ToxinPred, PepCalc, AllergenFP tools were utilized forecast physicochemical properties, toxicity, allergen Molecular docking analysis showed that six cationic could directly interact key sites...
The aim of this work is to evaluate the accuracy Barrett Universal II (BU II), Emmetropia verifying optical (EVO) 2.0, Haigis, Hoffer Q, QST (Savini/Taroni) (HQST), Holladay 1, Kane, Ladas Super, Sanders–Retzlaff–Kraff/theoretical (SRK/T), and T2 intraocular lens (IOL) power formulas for calculating spherical equivalent (SE) toric IOL. This study enrolled consecutive patients who underwent phacoemulsification IOL implantation at Eye Hospital Wenzhou Medical University in Hangzhou from 2015...
Cracking is a common failure mode in asphalt concrete (AC) pavements. Many tests have been developed to characterize the fracture behavior of AC. Accurate crack detection during testing crucial describe AC behavior. This paper proposed framework detect surface cracks specimens using two-dimensional digital image correlation (DIC). Two significant drawbacks previous research this field were addressed. First, multi-seed incremental reliability-guided DIC was solve decorrelation issue due large...
To shorten the complex and time-consuming process of identification method traditional food angiotensin-I-converting enzyme (ACE-I) inhibitory peptides, we propose AHTPeptideFusion based on a segmented fusion with protein language model deep learning. The statistical analysis found that hydrophobic amino acids, N-terminal valine is dominant acid in activity ACE-I peptides. In 12 machine learning (ML) algorithms, transformer outperformed other 11 models, best performance predicting short...
Introduction: Cataract surgery has been reported to have a reducing effect on intraocular pressure (IOP) in glaucomatous and non-glaucomatous eyes. This seems be more noticeable eyes with narrow angles (NAs) than open (OAs). Decrease IOP may result of the increase anterior chamber angle (ACA) Schlemm canal (SC) after cataract surgery. The purpose this paper is evaluate relationship between canal-cross-sectional area (SC-CSA) changes trabecular meshwork, ciliary muscle difference angles....
Abstract BACKGROUND Black rice anthocyanins (BRA) offer significant health benefits but are limited in application due to their low bioavailability. Bovine serum albumin (BSA) nanoparticles (NPs) have been shown effectively enhance the stability of encapsulated BRA. However, mechanism BRA‐BSA NP formation and molecular interactions remain unclear. This study prepared characterized NPs investigated mechanisms using computational simulations. RESULTS The optimized had a particle size 128.37 ±...
Inhibition of pancreatic lipase can be effective in controlling or treating obesity. Phenolic acids have good inhibitory effects and are widely found plants. The identification phenolic their derivatives that efficiently inhibit has attracted widespread attention. Therefore, it is crucial to screen natural inhibitors by establishing quantitative structure-activity relationships (QSAR) models. In this study, machine learning was used perform multiple computational analyses 28 with activity,...
Pancreatic lipase (PL) is a key hydrolase in lipid metabolism. Inhibition of PL activity can intervene obesity, global sub-health disease. The natural product considered good alternative to chemically synthesized drugs due its advantages, such as low side effects. However, traditional experimental screening methods are labor-intensive and cost-consuming, there an urgent need develop high-throughput for the discovery anti-PL products. In this study, virtual process products provided. Firstly,...
To investigate the age-related tilt and decentration of crystalline lenses using a swept-source optical coherence tomography biometer (SS-OCT) (CASIA2, Tomey Corp.).Eye Hospital, Wenzhou Medical University, Wenzhou, Zhejiang, China.Cross-sectional study.The direction magnitude lens were evaluated in 230 participants with ages ranging from 7 to 90 years SS-OCT. The divided into 4 age groups, differences among groups analyzed. Multiple linear regression was used main factors influencing...
Asphalt concrete (AC) aging reduces the resistance of flexible pavements to fatigue, thermal, and block cracking. Therefore, it is critical understand effects AC on pavement serviceability. Binder source has a significant effect long-term aging. necessary develop reliable, practical, systematic method quantify binder cracking resistance. Seven laboratory mixes were designed produced at three asphalt replacement (ABR) levels using various binders, but same performance grade (PG). The tested...
This article proposes a deep neural network, namely CrackPropNet, to measure crack propagation on asphalt concrete (AC) specimens. It offers an accurate, flexible, efficient, and low-cost solution for measurement using images collected during cracking tests. CrackPropNet significantly differs from traditional learning networks, as it involves locate displacement field discontinuities by matching features at various locations in the reference deformed images. An image library representing...
Two-dimensional digital image correlation (2D-DIC) is a widely used optical technique to measure displacement and strain during asphalt concrete (AC) testing.An accurate 2-D DIC measurement can only be achieved when the camera's principal axis perpendicular planar specimen surface.However, this requirement may not met testing due device constraints.This paper proposes simple reliable method correct errors induced by non-perpendicularity.The based on feature matching rectification.No...
Resurfacing a moderately deteriorated Portland cement concrete (PCC) pavement with asphalt (AC) layers is considered an efficient rehabilitation practice. However, reflective cracks may develop shortly after resurfacing because of discontinuities (e.g. joints and cracks) in existing PCC pavement. In this paper, new accelerated full-scale testing approach was developed to study crack growth AC overlays. Two hydraulic actuators were used simulate moving dual-tire assembly loading rate more...
Flavonoids, especially their inhibitory effect on DPP-IV activity, have been widely recognized for antidiabetic effects. However, the variety of natural flavonoid derivatives is very rich, and even subtle structural differences can lead to several orders magnitude in activities against DPP-IV, which makes it challenging find novel potent anti-DPP-IV experimentally. Therefore, there an urgent need develop efficient screening pipeline that targets active products. Here, we propose a fusion...
Purpose: To evaluate the agreement between anew UBM and an SS-OCT.Methods: The scans of right eye each volunteer were obtained using two devices. Data fitted recorded including: central corneal thickness (CCT), aqueous depth (AQD) (the distance from endothelium to lens), angle-to-angle (ATA), lens (LT), diameter in horizontal direction (LDiaangle: sharp angles on both sides lens, LDiaarc: vertex circular arcs anterior posterior radius (Rf Rb).Results: 25 eyes included this study. It could be...
Purpose: To evaluate the dependence of biomechanical metrics on intraocular pressure (IOP). Methods: 233 refractive surgery patients were included in this study-all examined 3 times with Corvis ST before and after dilation, differences (∆) main device parameters assessed. The data collected biomechanically corrected IOP (bIOP), central corneal thickness (CCT), six dynamic response (DCR) parameters, namely DA, DARatio2mm, IIR, SP-A1, CBI, SSI. Participants divided into three groups according...