- Diabetes Management and Research
- Diabetes Treatment and Management
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Gestational Diabetes Research and Management
- Diabetes and associated disorders
- Diet and metabolism studies
- Metabolism, Diabetes, and Cancer
- Adipokines, Inflammation, and Metabolic Diseases
- Hyperglycemia and glycemic control in critically ill and hospitalized patients
- Adipose Tissue and Metabolism
- Oral microbiology and periodontitis research
- Diabetic Foot Ulcer Assessment and Management
- Botulinum Toxin and Related Neurological Disorders
- Salivary Gland Disorders and Functions
- Skin Diseases and Diabetes
- Pharmacology and Obesity Treatment
- Urinary Bladder and Prostate Research
- Pregnancy and preeclampsia studies
- Cardiovascular Function and Risk Factors
- Neurological Disorders and Treatments
- Diabetes Management and Education
- Pancreatitis Pathology and Treatment
- Neurological disorders and treatments
- Obesity, Physical Activity, Diet
- Bariatric Surgery and Outcomes
Istanbul University
2016-2025
Sağlık Bilimleri Üniversitesi
2020
There is concern about an emerging diabetes epidemic in Turkey. We aimed to determine the prevalence of diagnosed and undiagnosed diabetes, prediabetes their 12-year trends identify risk factors for adult Turkish population. A cross-sectional, population-based survey, 'TURDEP-II' included 26,499 randomly sampled adults aged ≥ 20 years (response rate: 87 %). Fasting glucose biochemical parameters were measured all; then a OGTT was performed eligible participants. The 16.5 % (new 7.5 %),...
OBJECTIVES—To investigate for the first time prevalence of diabetes and impaired glucose tolerance (IGT) nationwide in Turkey; to assess regional variations relationships between intolerance lifestyle physical risk factors. RESEARCH DESIGN AND METHODS—The Turkish Diabetes Epidemiology Study (TURDEP) is a cross-sectional, population-based survey that included 24,788 subjects (age ≥20 years, women 55%, response 85%). Glucose was classified according World Health Organization recommendations on...
Background: The aim of this study was to determine whether detectable periodontal destruction and alterations in the salivary status were present with duration diabetes children type 1 insulin‐dependent mellitus (type DM) as compared healthy controls. Methods: Sixteen newly diagnosed DM (group 1), 16 long 2), 3) participated study. Periodontal health assessed by plaque index, gingival bleeding on probing, probing depths. flow rate, pH, buffering capacity, peroxidase activities stimulated...
In this split-mouth clinical trial, we evaluated the benefits of low-level laser therapy (LLLT) as an adjunct to nonsurgical periodontal treatment in patients with type 2 diabetes mellitus (DM).The impaired wound healing seen diabetic may affect results and require additional approach.In total, 22 chronic periodontitis DM were included. Applying a design, two quadrants treated only scaling root planing (SRP) control those other SRP + LLLT test sites each patient. An 808 nm GaAlAs diode was...
Fasting plasma glucose (FPG) and hemoglobin A1c (HbA1c) have been used to diagnose new-onset diabetes mellitus (DM) in order simplify the diagnostic tests compared with 2-hour oral tolerance test (OGTT; 2-hPG). We aimed identify optimal cut-off points of high sensitive C-reactive protein (hs-CRP) DM people based on FPG, 2-hPG, or HbA1c methods. Data derived from recent population-based survey Turkey (TURDEP-II). The study included 26,499 adult (63% women, response rate 85%). mean serum...
Motor unit number estimation (MUNE) methods including the one using F-waves (F-MUNE) are used to detect axonal loss in polyneuropathies. The aim of this study is evaluate amount by repeater F-wave parameters and F-MUNE patients with type 2 diabetes mellitus (DM). In 24 controls 49 diabetic polyneuropathy, 90 elicited supramaximal 300 submaximal stimulation ulnar nerve were recorded from abductor digiti minimi muscle. values calculated automated software stimulation. Ulnar index neuron found...
Background and Aims: The age-at-onset is of great importance in the heterogeneity Type 1 diabetes mellitus (T1DM). This study was designed to define clinical laboratory differences between child-adolescent-onset adult-onset T1DM at presentation during follow-up determine predicting factors for developing microvascular macrovascular complications. Material Methods: retrospective observational evaluated patients who were followed outpatient clinic January 1, 2000, December 31, 2019. Results:...
Abstract Objective. In this retrospective observational study, we aimed to evaluate the impact of insulin degludec/insulin aspart (IDegAsp) treatment on glycemic status, metabolic parameters, and weight/body mass index (BMI) change at a single tertiary diabetes center in Turkey. Methods. We conducted cohort study patients with type 2 who received IDegAsp between October 2018 November 2019 outpatient clinic. The had inadequate responses (HbA1c ≥8%) least 3 months experienced (± oral...
In this study, salivary peroxidase activity was measured in a group of 10 patients with insulin-dependent (type I) diabetes mellitus (IDDM) who had tendency towards periodontitis. healthy subjects (N : 10), mean 0.0025 +/- 0.001 IU/ml, while type I diabetic it 0.051 0.015 significantly higher level (p < 0.001). Approximal plaque index (API), modified sulcus bleeding (mod SBI) and pocket depths were assessed clinically. The values for mod SBI API 60% 68% respectively the control 0.0% value...
To compare the effect of acarbose and gliclazide on clinical findings, biochemical parameters safety in type 2 diabetic patients insufficiently controlled with medical nutrition therapy (MNT).Seventy-two (age 35-70 years, BMI < or = 35 kg/m2), who had not taken any oral antidiabetic drug previously, were randomised into two groups after a four-week placebo period, treated for 24 weeks (100 mg to three times daily) (40-80 twice daily). The study was open 57 (33 males females) completed it....
Targeting better glycated hemoglobin (HbA1c) and blood pressure (BP) goals may endanger older adults with type 2 diabetes mellitus (T2DM). Overtreatment of T2DM hypertension is a trending issue, although undertreatment still common. We investigated the rates predictors overtreatment glycemia BP in physicians' attitudes to deintensify or intensify treatment. Data from (≥ 65 years) enrolled large nationwide survey 2017 across Turkey were analyzed. was defined as HbA1c < 6.5% plus use ≥ oral...
Searchable abstracts of presentations at key conferences in endocrinology ISSN 1470-3947 (print) | 1479-6848 (online)
Background: It has been shown that the synthesis and secretion of cytokines is influenced by imbalance in oxidant/antioxidant status. In this study, relation between circulating levels oxidative stress biomarkers proinflammatory was searched gestational diabetes mellitus (GDM) patients order to evaluate possible role ongoing condition impaired glucose homeostasis. Methods findings: 33 pregnant women with GDM 20 free any maternal or fetal disorders were included study. Visfatin, TNF-α, IL-1β,...
People with impaired glucose tolerance are considered to be prone diabetes. To evaluate their visual function we investigated colour vision the Farnsworth-Munsell 100 Hue test and contrast sensitivity Arden's grating cards in people imparied (IGT), normal (NGT) others type II diabetes (NIDDM). Eyes low or any anterior posterior segment abnormalities were excluded. Contrast color differed significantly between groups (p < 0.01). It thus appears that patients IGT but without clinical could...
Alstrom syndrome is a rare disorder characterized by early obesity, loss of central vision, diabetes mellitus, hearing and short stature. Previous studies, have reported no information regarding oral findings. This article describes findings in two cases syndrome. In both cases, gingivitis was present also light yellowbrown discolored enamel bands were observed on the anterior teeth. staining may resulted from discoloration preexisting slight band-like hypoplasia. The gingiva examined...
The aim of the study was to compare lower urinary tract symptoms (LUTS) in women with and without type 2 diabetes mellitus (DM).The sample drawn from community-dwelling province Istanbul who were cared for outpatient clinic Medical School between January June 2012. Two hundred forty-nine DM compared 255 obstetrics gynecology department same university hospital. mean ages groups 55.1 53.7 years, respectively.Participants completed a questionnaire that queried sociodemographic clinical...