A5050693010- Pituitary Gland Disorders and Treatments
- Growth Hormone and Insulin-like Growth Factors
- Adrenal and Paraganglionic Tumors
- Parathyroid Disorders and Treatments
- Thyroid Cancer Diagnosis and Treatment
- Ophthalmology and Eye Disorders
- Bone health and treatments
- Vitamin D Research Studies
- Neuroendocrine Tumor Research Advances
- Thyroid Disorders and Treatments
- Medical Imaging and Pathology Studies
- Bariatric Surgery and Outcomes
- Diabetes and associated disorders
- Diabetes Management and Research
- Gestational Diabetes Research and Management
- Bone health and osteoporosis research
- Diet and metabolism studies
- Cardiovascular Disease and Adiposity
- Thyroid and Parathyroid Surgery
- Child Abuse and Related Trauma
- Metabolism, Diabetes, and Cancer
- Obesity and Health Practices
- Adenosine and Purinergic Signaling
- Adrenal Hormones and Disorders
- Cerebral Venous Sinus Thrombosis
Istanbul University
2012-2025
Başkent University
2018
Institut des Maladies Métaboliques et Cardiovasculaires
2017
Dopamine agonist (DA)-induced impulse control disorder (ICD) in patients with prolactinomas is not sufficiently known. To evaluate the prevalence of DA-induced ICDs and possible risk factors related to these disorders prolactinoma. This a cross-sectional multicenter study involving 308 prolactinoma followed up tertiary referral centers who received at least three months DA therapy. (pathological gambling, hypersexuality, compulsive shopping, eating) impulsivity were assessed using...
Background and Aims: The age-at-onset is of great importance in the heterogeneity Type 1 diabetes mellitus (T1DM). This study was designed to define clinical laboratory differences between child-adolescent-onset adult-onset T1DM at presentation during follow-up determine predicting factors for developing microvascular macrovascular complications. Material Methods: retrospective observational evaluated patients who were followed outpatient clinic January 1, 2000, December 31, 2019. Results:...
Objective The aim of this study was to determine the frequency central thyroid dysfunctions in Cushing's syndrome (CS). We also aimed evaluate hyperthyroidism due inappropriate secretion TSH (SITSH), which recently defined patients with insufficient hydrocortisone replacement after surgery. Materials and methods evaluated functions (TSH free thyroxine [fT4]) at time diagnosis, during hypothalamo-pituitary-adrenal axis recovery, surgery 35 CS. were separated into two groups: ACTH-dependent CS...
The granulation pattern of pituitary tumors may be important to predict tumor behavior, treatment outcomes, and recurrences. Therefore, we compared densely granulated corticotroph (DGCT) sparsely (SGCT) in terms clinicopathologic findings.A total 41 patients (31 females/10 males) were assessed the study. patterns detected by Periodic Acid-Schiff (PAS) adrenocorticotropic hormone (ACTH) immunoreactivity. Diffuse strong staining PAS ACTH identified as DGCT, whereas faint focal, weak SGCT....
In this study, we aimed to evaluate the presence of glucose metabolism abnormalities and their impact on IGF-1 levels in patients with acromegaly. Ninety-three acromegaly (n=93; 52 males/41 females) were included study. Patients separated into three groups such as; normal tolerance (n=23, 25%), prediabetes (n=38, 41%), diabetes mellitus (n=32, 34%). Insulin resistance was calculated homeostasis model assessment (HOMA). HOMA-IR > 2.5 or ≤2.5 defined as insulin resistant noninsulin groups,...
Abstract Introduction Genetic mutations such as C599T polymorphism in glutathione peroxidase [GPX1] gene and polymorphisms potassium channel (KCNJ11) genes have recently been proposed the etiopathogenesis of new onset diabetes mellitus after renal transplantation (NODAT). We aimed to examine association GPX1 KCNJ11 NODAT. Materials Methods This is a monocenter case-control study with total 118 transplant recipients who were divided into 2 groups; NODAT normal glucose tolerance. Relation...
What is known and objective Somatostatin analogs control GH/IGF-1 excess in acromegaly. receptors also mediate the complex effects of somatostatin on gastrointestinal tract may be defensive inflammatory bowel diseases, such as ulcerative colitis. We present a patient who showed good response to long-acting octreotide (OCT-LAR) treatment terms both acromegaly colitis (UC). Case summary A 58-year-old female with diagnosis was started first-line for she refused undergo transsphenoidal surgery....
Abstract The aim of this study was to evaluate the efficacy cabergoline in normalizing plasma IGF-I levels acromegaly patients with elevated after surgery and/or SRL therapy. Acromegaly (n: 143) were evaluated retrospectively. Patients SRLs therapy and a fixed dose treatment for last six months no history radiotherapy three years included 12). Previous regimens, baseline PRL (ULNR), sella MRI, immunohistochemical findings evaluated. Cabergoline used as an add on 11) or single medical 1)....
To determine risk factors associated with the development of insulin resistance, type 2 diabetes mellitus (T2DM), and metabolic syndrome (MetS) in gestational (GDM) patients 10 years after giving birth.
The role of severity and duration inflammatory findings on the development persistent hypothyroidism anemia has not been clarified in subacute thyroiditis (SAT).
Introduction:Insulinoma is a rare disease, however the most common cause of hypoglycemia due to excess insulin secretion.Diagnosis and localization can be challenging.This study evaluated clinical features, diagnostic workup, management, outcomes patients with insulinoma.Methods: The records 13 insulinoma who were followed up at İstanbul University, Faculty Medicine retrospectively reviewed. Results:The mean age (female/male: 11/2) was 43.9±12.5 years diagnosis.The tumor diameter 14.3±6.7 mm...
Familial hypercholesterolemia (FH) is a genetic disorder associated with extremely high levels of low-density lipoprotein cholesterol (LDL-C) and increased incidence cardiovascular disease. We aimed to evaluate the efficacy long-term outcomes apheresis (LA) in treatment FH. Cardiovascular events that occurred before after LA were evaluated by reviewing previous medical records patients Thirteen (female/male: 8/5) included this study. The mean Dutch score was 20±4. All treated combination...