- COVID-19 epidemiological studies
- Mathematical and Theoretical Epidemiology and Ecology Models
- Evolution and Genetic Dynamics
- Viral Infections and Outbreaks Research
- COVID-19 Pandemic Impacts
- Viral Infections and Vectors
- SARS-CoV-2 and COVID-19 Research
- Data-Driven Disease Surveillance
- Mosquito-borne diseases and control
- Influenza Virus Research Studies
- Zoonotic diseases and public health
- Virology and Viral Diseases
- Disaster Response and Management
- Research on Leishmaniasis Studies
- Trypanosoma species research and implications
- COVID-19 impact on air quality
- Animal Disease Management and Epidemiology
- Vaccine Coverage and Hesitancy
- COVID-19 Clinical Research Studies
- Viral Infections and Immunology Research
- Vibrio bacteria research studies
- COVID-19 Digital Contact Tracing
- Dengue and Mosquito Control Research
- Cerebral Palsy and Movement Disorders
- Antibiotic Use and Resistance
Cleveland State University
2023-2025
Shanghai Normal University
2016-2023
University of Hong Kong
2020-2022
Hong Kong Polytechnic University
2017-2022
Chinese University of Hong Kong
2020-2022
Hong Kong Science and Technology Parks Corporation
2022
Laboratory of Data Discovery for Health
2022
Columbus State University
2022
Tel Aviv University
2022
Shanxi University
2022
In December 2019, an outbreak of respiratory illness caused by a novel coronavirus (2019-nCoV) emerged in Wuhan, China and has swiftly spread to other parts number foreign countries. The 2019-nCoV cases might have been under-reported roughly from 1 15 January 2020, thus we estimated the unreported basic reproduction number, R0, 2019-nCoV.We modelled epidemic curve cases, mainland 2019 24 2020 through exponential growth. was determined maximum likelihood estimation. We used serial intervals...
The ongoing Zika virus (ZIKV) epidemic poses a major global public health emergency. It is known that ZIKV spread by \textit{Aedes} mosquitoes, recent studies show can also be transmitted via sexual contact and cases of sexually have been confirmed in the U.S., France, Italy. How transmission affects control infection not well-understood. We presented mathematical model to investigate impact mosquito-borne on used fit data Brazil, Colombia, El Salvador. Based estimated parameter values, we...
Abstract Backgrounds An ongoing outbreak of a novel coronavirus (2019-nCoV) pneumonia hit major city China, Wuhan, December 2019 and subsequently reached other provinces/regions China countries. We present estimates the basic reproduction number, R 0 , 2019-nCoV in early phase outbreak. Methods Accounting for impact variations disease reporting rate, we modelled epidemic curve cases time series, mainland from January 10 to 24, 2020, through exponential growth. With estimated intrinsic growth...
In this paper, we propose a multi-patch model to study the effects of population dispersal on spatial spread malaria between patches. The basic reproduction number [Formula: see text] is derived and it shown that disease-free equilibrium locally asymptotically stable if unstable text]. Bounds are given. A sufficient condition for existence an endemic when obtained. For two-patch submodel, dependence movement exposed, infectious, recovered humans two patches investigated. Numerical...
Background Yellow fever (YF), transmitted via bites of infected mosquitoes, is a life-threatening viral disease endemic to tropical and subtropical regions Africa South America. YF has largely been controlled by widespread national vaccination campaigns. Nevertheless, between December 2015 August 2016, resurged in Angola, quickly spread became the largest outbreak for last 30 years. Recently, again Brazil (December 2016). Thus, there an urgent need gain better understanding transmission...
The coronavirus disease 2019 (COVID-19) was first identified in Wuhan, China on December patients presenting with atypical pneumonia. Although 'city-lockdown' policy reduced the spatial spreading of COVID-19, city-level outbreaks within each city remain a major concern to be addressed. local or regional level control mainly depends individuals self-administered infection prevention actions. contradiction between choice taking actions not makes elimination difficult under voluntary acting...
Abstract Backgrounds The emerging virus, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has caused a large outbreak of novel disease (COVID-19) in Wuhan, China since December 2019. Based on the publicly available surveillance data, we identified 21 transmission chains Hong Kong and estimated serial interval (SI) COVID-19. Methods Index cases were reported after symptoms onset, contact tracing was conducted to collect data associated secondary cases. An censored likelihood...
This paper is devoted to studying the impact of human behavior on cholera infection. We start with a ordinary differential equation (ODE) model that incorporates via modeling disease prevalence dependent contact rates for direct and indirect transmissions infectious host shedding. Local global dynamics are analyzed respect basic reproduction number. then extend ODE reaction–convection–diffusion partial (PDE) accounts movement both hosts bacteria. Particularly, we investigate spreading speed...
Background: The emerging virus, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has caused a large outbreak of novel disease (COVID-19) in Wuhan, China since December 2019. As February 15, there were 56 COVID-19 cases confirmed Hong Kong the first case with symptom onset on January 23, 2020. Methods: Based publicly available surveillance data, we identified 21 transmission events, which occurred Kong, and had primary known, as An interval censored likelihood framework is...
Empirical and statistical evidence suggests that the number of trips taken per year varies significantly among people by age, gender, income, occupation, ethnicity, region, so on. Only a small fraction are frequent travelers while most travel occasionally or never. Taking difference in frequency into consideration, we propose multipatch epidemic model where humans each patch divided susceptible unfrequent, infectious frequent, classes. The basic reproduction $\mathcal{R}_0$ is derived shown...
Background Over-prescribing of antibiotics is considered to result in increased morbidity and mortality from drug-resistant organisms. A resulting common wisdom that it would be better for society if physicians restrain their prescription antibiotics. In this view, self-interest societal interest are at odds, making antibiotic use a classic “tragedy the commons”. Methods Findings We developed two mathematical models transmission resistance, featuring de novo development resistance resistant...
We compared the COVID-19 and 1918-19 influenza pandemics in United Kingdom. found that ongoing wave of infection matched major pandemic surprisingly well, with both reaching similar magnitudes (in terms estimated weekly new infections) spending same duration over five cases per 1000 inhabitants previous two months. also discussed similarities epidemiological characteristics between these pandemics.
Related DatabasesWeb of Science You must be logged in with an active subscription to view this.Article DataHistorySubmitted: 13 December 2019Accepted: 09 June 2020Published online: 22 September 2020Keywordshuman movement, infection size, disease prevalence, basic reproduction number, diffusion coefficient, endemic equilibriumAMS Subject Headings92D30, 91D25, 34C60, 34D05, 37N25Publication DataISSN (print): 0036-1399ISSN (online): 1095-712XPublisher: Society for Industrial and Applied...
To model estimated deaths averted by COVID-19 vaccines, we used state-of-the-art mathematical modeling, likelihood-based inference, and reported death vaccination data. We that >1.5 million were in 12 countries. Our can help assess effectiveness of the program, which is crucial for curbing pandemic.