A5052830125- Shoulder Injury and Treatment
- Tendon Structure and Treatment
- Sports injuries and prevention
- Osteoarthritis Treatment and Mechanisms
- Total Knee Arthroplasty Outcomes
- Lymphatic System and Diseases
- Muscle Physiology and Disorders
- Adipose Tissue and Metabolism
- Exercise and Physiological Responses
- Advanced Neural Network Applications
- Glioma Diagnosis and Treatment
- Infrastructure Maintenance and Monitoring
- Lower Extremity Biomechanics and Pathologies
- Angiogenesis and VEGF in Cancer
Copenhagen University Hospital
2022-2025
Frederiksberg Hospital
2022-2025
University of Copenhagen
2024
Danish Cancer Society
2018
Glioblastoma ranks among the most lethal cancers, with current therapies offering only palliation. Paracrine vascular endothelial growth factor (VEGF) signaling has been targeted using anti-angiogenic agents, whereas autocrine VEGF/VEGF receptor 2 (VEGFR2) is poorly understood. Bevacizumab resistance of VEGFR2-expressing glioblastoma cells prompted interrogation VEGF-C/VEGFR2 in glioblastoma.Autocrine was functionally investigated RNA interference and exogenous ligands patient-derived...
Abstract Muscle fibre denervation and declining numbers of muscle stem (satellite) cells are defining characteristics ageing skeletal muscle. The aim this study was to investigate the potential for lifelong recreational exercise offset compromised satellite cell content function, both at rest under challenged conditions. Sixteen elderly exercisers (LLEX) were studied alongside groups age‐matched sedentary (SED) young subjects. Lean body mass maximal voluntary contraction assessed, a strength...
ABSTRACT Knowledge of how to treat chronic tendinopathy has advanced in recent years, but the treatment early is not well understood. The main purpose this prospective observational study was investigate if changes occur clinical and imaging outcomes over 12 weeks elite athletes with debut tendinopathy. Sixty‐five adult (24 ± 5 years) Achilles or patellar (symptoms < 3 months) were examined at baseline after weeks. Patients divided into groups based on duration symptoms time inclusion:...
UNet has become the gold standard method for segmenting 2D medical images that any new must be validated against. However, in recent years, several variations of seminal have been proposed with promising results. there is no clear consensus on generalisability these architectures, and currently remains methodological standard. The purpose this study was to evaluate some most UNet-inspired architectures 3D segmentation. For segmentation scans, methods are also dominant, but a larger variety...
Abstract The UNet has become the golden standard method for segmentation of 2D medical images that any new must be validated against. In recent years, a number variations to seminal have been proposed with promising results in papers introducing them. However, there is no clear consensus if these architectures generalize as well and currently remains methodological standard. For 3D scans, UNet‐inspired methods are also dominant, but larger variety across applications. By evaluating different...