A5100319391- Metal-Organic Frameworks: Synthesis and Applications
- Magnetism in coordination complexes
- Infant Nutrition and Health
- RNA Interference and Gene Delivery
- Polyamine Metabolism and Applications
- Metal complexes synthesis and properties
- Mosquito-borne diseases and control
- Advanced biosensing and bioanalysis techniques
- Andrographolide Research and Applications
- Fatty Acid Research and Health
- Polyoxometalates: Synthesis and Applications
- Nanoparticle-Based Drug Delivery
- Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Digital Communication and Language
- Chemical Synthesis and Analysis
- Discourse Analysis in Language Studies
- Food Allergy and Anaphylaxis Research
- Antibiotic Resistance in Bacteria
- Sulfur-Based Synthesis Techniques
- Nanoplatforms for cancer theranostics
- Inflammasome and immune disorders
- Mindfulness and Compassion Interventions
- RNA regulation and disease
- Iron Metabolism and Disorders
- Carbohydrate Chemistry and Synthesis
Sun Yat-sen University
2007-2025
Hong Kong Polytechnic University
2024
University of North Carolina at Chapel Hill
2021-2024
Peking University
2024
National Sun Yat-sen University
2022
Zhejiang Pharmaceutical College
2021
Guangzhou Medical University
2016-2021
First Affiliated Hospital of Guangzhou Medical University
2016-2021
Sichuan University
2019
Sun Yat-sen Memorial Hospital
2019
Highly ordered three-dimensional α-Fe2O3@PANI core-shell nanowire arrays with enhanced specific areal capacity and rate performance are fabricated by a simple cost-effective electrodeposition method. The provide large reaction surface area, fast ion electron transfer, good structure stability, which all beneficial for improving the electrochemical performance. Here, high-performance asymmetric supercapacitors (ASCs) designed using as anode PANI nanorods grown on carbon cloth cathode, they...
Drug resistance, developed through multiple mechanisms, is a major hindrance to successful chemotherapy of tumor. Combination therapy chemotherapeutic drugs and siRNA represents an emerging strategy which may improve anticancer effect by synergistic actions. In this study, triblock copolymer poly(ethylene glycol)- block-poly(l-lysine)- block-poly aspartyl ( N-( N', N'-diisopropylaminoethyl)) (PEG-PLL-PAsp(DIP)) was synthesized for the first time enable codelivery BCL-2 DOX. The system...
A novel liposomal system incorporating branched PEI was prepared to efficiently codeliver sorafenib and GPC3 siRNA for hepatocellular carcinoma therapy.
A new series of oxovanadium(IV)-lanthanide(III) heteronuclear complexes [Yb(H2O)8]2[(VO)2(TTHA)](3)21 H2O (1), {[Ho(H2O)7(VO)2(TTHA)][(VO)2(TTHA)](0.5)} 8.5 (2), {[Gd(H2O)7(VO)2(TTHA)][(VO)2(TTHA)](0.5)}8.5 (3), {[Eu(H2O)7][(VO)2(TTHA)](1.5)} 10.5 (4), and [Pr2(H2O)6(SO4)2][(VO)2(TTHA)] (5) (H6TTHA=triethylenetetraaminehexaacetic acid) were prepared by using the bulky flexible organic acid H(6)TTHA as structure-directing agent. X-ray crystallographic studies reveal that they contain same...
Due to limited light penetration and dependence on oxygen, photodynamic therapy (PDT) is typically restricted treating shallow tissues. Developing strategies overcome these limitations effectively using PDT for tumor treatment a significant yet unresolved challenge. In this study, we present smart approach combining wireless-charged LED (wLED) with type I aggregation-induced emission photosensitizer, MeOTTMN, address both hypoxia issues simultaneously. characterized by twisted molecular...
Background: Medium- and long-chain triacylglycerols (MLCTs) sn-2 palmitate constitute approximately 70~80% of total breast milk fat. The structured lipid MLCTs palmitate, mimicking human milk, have demonstrated improvement in absorption energy metabolism vitro animal experiments. However, clinical trials on infant formula supplied with yet to be conducted. Objectives: This study was designed evaluate the effects growth a novel healthy infants born at term. Methods: Infants were enrolled 30 d...
An impermeable outer membrane and multidrug efflux pumps work in concert to provide Gram-negative bacteria with intrinsic resistance against many antibiotics. These mechanisms reduce the intracellular concentrations of antibiotics render them ineffective. The natural product thiomarinol A combines holothin, a dithiolopyrrolone antibiotic, marinolic acid A, close analogue mupirocin. hybridity converts mupirocin scaffold from inhibiting Gram-positive both -negative bacteria. We found that...
pH and reduction dual-sensitive polymeric nanovesicles were developed to simultaneously deliver hydrophobic gefitinib hydrophilic doxorubicin for cancer therapy.
Abstract Dinuclear and one‐dimensional copper complexes [Cu 2 (tpa) ( m ‐bda)](ClO 4 ) 1 ), [{Cu (tpm) ‐bda) } · CH 3 OH H O] n (bpm) (H O)} CN [tpa: tris(2‐pyridylmethyl)amine; tpm: tris(pyrazolyl)methane; bpm: bis(pyrazolyl)methane; ‐bda: isophthalate dianion] have been prepared from various polydentate terminal ligands. Complex crystallizes in the monoclinic P / c space group with a = 14.003(6), b 17.201(7), 20.654(9) Å, Z 4, R 0.0678, wR 0.1751. triclinic $\tilde {1}$ 10.250(7),...
Dengue virus (DENV) utilizes host factors throughout its life cycle. In this study, we identified RNA helicase A (RHA), a member of the DEAD/H family, as an important factor DENV. response to DENV2 infection, nuclear RHA protein was partially redistributed into cytoplasm. The short interfering RNA-mediated knockdown significantly reduced amounts infectious viral particles in various cells. multistep growth and Japanese encephalitis but not Zika virus. Further study showed that absence...
Combination therapy is an effective strategy to combat antibiotic resistance. Multiple synergistic antimicrobial combinations are produced by enzymes encoded in biosynthetic gene clusters (BGCs) that co-localize on the bacterial genome. This phenomenon led hypothesis mining co-localized BGCs will reveal new of natural products. Here, we bioinformatically identified 38 pairs BGCs, which predict produce products related known compounds, including polycyclic tetramate macrolactams (PoTeMs). We...
Purpose: To aim of the study was to analyze virtual reality (VR) for cultural heritage preservation in China. Methodology: This adopted a desk methodology. A research design is commonly known as secondary data collection. basically collecting from existing resources preferably because its low cost advantage compared field research. Our current looked into already published studies and reports easily accessed through online journals libraries. Findings: Virtual Reality has emerged potent tool...
Abstract The first ferromagnetic coupled, thiocyanato‐bridged copper( II )‐manganese( ) bimetallic 2D polymer {[Cu(ipa) 2 ] Mn(NCS) 6 ·2H O} n (ipa = 1,2‐propanediamine) has been synthesised and characterised by a single‐crystal X‐ray structure determination variable temperature magnetic susceptibility studies. (© Wiley‐VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2005)
Abstract Three novel compounds with bridging dichromate anions the formulae [Fe(4,4′‐bpy) 2 Cr O 7 ] n ( 1 ), [Co(4,4′‐bpy) and [Ni(dpa) ]·H 3 ) (4,4′‐bpy = 4,4′‐bipyridine, dpa 2,2′‐dipyridylamine) have been synthesized characterized. The isostructural belong to monoclinic space group C 2/ c shown be three‐dimensional polymers in which connect neighboring layers formed by [M(4,4′‐bpy) 2+ (M Fe, Co) units. Compound is a metalla‐crown type compound, crystallizing P / . Two chromate link two...
Amide N-methylation is important for the activity and permeability of bioactive compounds but can be challenging to perform selectively. The broad-spectrum antimicrobial natural products thiolutin holomycin differ only by an N-methyl group at endocyclic amide thiolutin, exhibits antifungal activity. enzyme responsible N--methylation in biosynthesis has remained elusive. Here, we identified characterized N-methyltransferase DtpM that encoded >400 kb outside gene cluster. catalyzes efficient...