- Advanced biosensing and bioanalysis techniques
- Biosensors and Analytical Detection
- DNA and Nucleic Acid Chemistry
- RNA Interference and Gene Delivery
- Molecular Sensors and Ion Detection
- Viral Infections and Immunology Research
- Mycotoxins in Agriculture and Food
- MicroRNA in disease regulation
- Mosquito-borne diseases and control
- Cytomegalovirus and herpesvirus research
- Electrochemical sensors and biosensors
- Nanocluster Synthesis and Applications
Shandong University of Traditional Chinese Medicine
2023-2025
Affiliated Hospital of Shandong University of Traditional Chinese Medicine
2023-2025
Shandong University
2020-2024
Ultrasensitive detection of the H5N1 nucleic acid fragment by ICP-MS using DNA dendrimer-carried AgNP labeling was developed. This approach enabled significant signal amplification, while magnetic separation effectively suppressed background signals.
The detection of Zika virus (ZIKV) is great significance to human life and health. Herein, we presented an ICP-MS fluorescent dual-mode sensor for quantitative analysis RNA fragments (ZIKV-RNA), which employed quantum dots (QDs) as signal tags combined with hybridization chain reaction (HCR). realized cross-checking the results improved assay accuracy. Firstly, single-stranded DNA (ssDNA) was anchored on surface magnetic beads (MBs). Afterward, HCR conducted probe DNA-CdSe conjugates...