A5102879151- Cardiac pacing and defibrillation studies
- Retinal and Optic Conditions
- Genetic factors in colorectal cancer
- Education Systems and Policy
- Cardiac Imaging and Diagnostics
- Atrial Fibrillation Management and Outcomes
- Spine and Intervertebral Disc Pathology
- Shoulder Injury and Treatment
- Cardiac Arrhythmias and Treatments
- Multilingual Education and Policy
- Pain Management and Treatment
- Educational Assessment and Improvement
- Cardiovascular Function and Risk Factors
- Retinal Imaging and Analysis
- Retinal Diseases and Treatments
- Tendon Structure and Treatment
- Heart Failure Treatment and Management
- Cardiac Valve Diseases and Treatments
- Cardiac, Anesthesia and Surgical Outcomes
- Higher Education Research Studies
- DNA Repair Mechanisms
- Virology and Viral Diseases
- Diverse Educational Innovations Studies
- RNA Research and Splicing
- Entrepreneurship Studies and Influences
Hasbro Children's Hospital
2025
Brown University
2025
University of Pennsylvania
2020-2024
New York University
2022-2023
Columbia University Irving Medical Center
2022
Texas A&M University
2021
Edward Hines, Jr. VA Hospital
2021
Wan Fang Hospital
2021
University of Michigan
2014-2020
California State University, Fullerton
2020
Osteoarthritis (OA) of the knee affects aging population and has an associated influence on health care system. Rigorous studies evaluating radiofrequency ablation for OA-related pain are lacking. This study compared long-term clinical safety effectiveness cooled (CRFA) with intra-articular steroid (IAS) injection in managing pain.This is a prospective, multicenter, randomized trial 151 subjects chronic (≥6 months) that was unresponsive to conservative modalities. Knee (Numeric Rating Scale...
Nipah virus (NiV) is a deadly emerging paramyxovirus. The NiV attachment (NiV-G) and fusion (NiV-F) envelope glycoproteins mediate both syncytium formation viral entry. Specific N-glycans on paramyxovirus proteins are generally required for proper conformational integrity biological function. However, removal of individual NiV-F had little negative effect processing or fusogenicity has even resulted in slightly increased fusogenicity. Here, we report that entry assays, multiple marked...
Significance The unfolded protein response of the endoplasmic reticulum (UPR ER ) is induced by proteotoxic conditions. Lipid disequilibrium also activates UPR , but whether this activation accompanied disturbed proteostasis in vivo remains controversial. In study, we show that nematode Caenorhabditis elegans compromised fatty acid desaturation and reduced phosphatidylcholine production activate without overt proteostatic imbalance, as assessed molecular, pharmacological, genetic analyses....
To investigate elevated intraocular pressures (IOP) (defined by a measurement >25 mmHg at follow-up visit) after an intravitreal injection of anti-vascular endothelial growth factor agents for age-related macular degeneration.Retrospective review medical records.A total 127 patients (155 eyes) received (bevacizumab, ranibizumab, or pegaptanib) ranging from 1 to 39 injections more than period 30 1759 days. Among this population, 12 (14 eyes; 9.4%) developed IOP mmHg. Of these, 7 (5.5%)...
As a follow-up to the 6-month report,12 this study investigated analgesic effect of cooled radiofrequency ablation (CRFA) in patients with knee osteoarthritis (OA) 12 months postintervention and its ability provide pain relief who experienced unsatisfactory effects intra-articular steroid injection (IAS).
ABSTRACT The cytoplasmic tails of the envelope proteins from multiple viruses are known to contain determinants that affect their fusogenic capacities. Here we report specific residues in tail Nipah virus fusion protein (NiV-F) modulate its activity. Truncation NiV-F greatly inhibited cell-cell fusion. Deletion and alanine scan analysis identified a tribasic KKR motif membrane-adjacent region as important for modulating K1A mutation increased 5.5-fold, while K2A R3A mutations decreased 3-...
This article reports the results of a survey third-grade teachers English Language Learners (ELLs) in Arizona regarding school language and accountability policies—Proposition 203, which restricts bilingual education mandates sheltered Immersion; federal No Child Left Behind Act 2001 (NCLB); LEARNS, state’s high-stakes testing program. The instrument, consisting 126 questions plus open-ended interview question, was designed to obtain teacher’s views, ascertain impact these polices, explore...
Preoperative cardiovascular risk stratification before noncardiac surgery is a common clinical challenge. Coronary artery calcium scores from ECG-gated chest computed tomography (CT) imaging are associated with perioperative events. At the time of preoperative evaluation, many patients will not have had CT imaging, but nongated studies performed for variety indications. We evaluated relationships between coronary severity estimated previous and major events (MCE) after surgery.
Subclinical atrial fibrillation (AF), in the form of cardiac implantable device-detected high rate episodes (AHREs), has been associated with increased thromboembolism. An cardioverter-defibrillator (ICD) lead a floating dipole may permit single (DX) ICD system to detect AHREs. We sought assess utility DX for subclinical AF detection patients, prospective multicenter, cohort-controlled trial.One hundred fifty patients without prior history (age 59 ± 13 years; 108 [72%] male) were enrolled...
Physics outreach programs provide a critical context for informal experiences that promote the transition from new student to contributing physicist. Prior studies have suggested positive link between participation in physics and development of student's identity. In this study, we adopt student-focused investigation explore effects on dimensions identity, sense community, 21st century skill development, motivation. We employed mixed methods study combining survey instrument (117 responses)...
Inactivation of DNA mismatch repair propels colorectal cancer (CRC) tumorigenesis. CRCs exhibiting elevated microsatellite alterations at selected tetranucleotide repeats (EMAST) show reduced nuclear MutS homolog 3 (MSH3) expression with surrounding inflammation and portend poor patient outcomes. MSH3 reversibly exits from the nucleus to cytosol in response proinflammatory cytokine interleukin-6 (IL-6), suggesting that may be a shuttling protein. In this study, we manipulated three putative...
Prior studies have shown that left ventricular diastolic dysfunction (DD) is associated with increased mortality after surgical aortic valve replacement but on transcatheter (TAVR) are limited and not taken into account mitral annular calcification (MAC), which limits the use of tissue Doppler imaging. We performed a single-center retrospective analysis to better evaluate role baseline DD outcomes TAVR.After excluding patients atrial fibrillation, prostheses significant stenosis, 359...
A comprehensive comparative study using qualitative methodology was conducted in Israel and the U.S. to examine goals that social workers seek achieve through intrapreneurship, measures of success for intrapreneurship motivations act as intrapreneurs. Categorical content analysis used identify recurring themes according predetermined questions. The research findings provide insights into role organizations work education systems designing policies promote involvement address complex ongoing problems.
Compartment syndrome of any extremity is a limb-threatening emergency requiring an emergent surgical management. Thus, ruling out compartment often high on the list priorities when treating high-energy injuries and fractures. However, even in most seemingly benign injuries, this dangerous diagnosis must always remain differential suspicion high.23-year-old factory worker presents after low energy entrapment injury to his left forearm. Initial work-up evaluation noted isolated radial head...
Unintended shocks from implantable cardioverter defibrillators (ICDs) are often distressing to patients and family members, particularly at the end of life. Unfortunately, a large proportion ICDs remain active time death among do not resuscitate (DNR) comfort care patients.We designed standardised teaching sessions for providers implemented novel decision tool in electronic medical record (EMR) improve frequency discussions surrounding ICD deactivation over 6-month period. The intended...
Background Mitral regurgitation ( MR ) has the potential to impede exercise capacity; it is uncertain whether this because of itself or underlying cause valvular insufficiency. Methods and Results The population comprised 3267 patients who underwent treadmill myocardial perfusion imaging transthoracic echocardiography within 6±8 days. was present in 28%, including 176 (5%) with moderate greater . Left ventricular systolic function significantly decreased chamber size increased relation ,...
Ablation of atrial tachycardia (AT) that occurs after cardiac surgery or prior ablation often requires complex lesion sets. In combination with the pre-existing scar, these sets may result in inadvertent intra-atrial conduction block. This study reports phenomenon incidental isolation right (RA) regions secondary to AT ablation, which some cases results profound bradycardia due sinus exit block.Intracardiac electrograms were examined consecutive patients who underwent RA. Cases localized RA...