- Cardiac Arrhythmias and Treatments
- Cardiac pacing and defibrillation studies
- Atrial Fibrillation Management and Outcomes
- Cardiovascular Disease and Adiposity
- Apelin-related biomedical research
- Cardiac electrophysiology and arrhythmias
- Cardiac Structural Anomalies and Repair
- Cardiovascular, Neuropeptides, and Oxidative Stress Research
- Biochemical and Structural Characterization
- Cardiac, Anesthesia and Surgical Outcomes
- Neurological disorders and treatments
- Aortic aneurysm repair treatments
- Cardiac Arrest and Resuscitation
- Adipokines, Inflammation, and Metabolic Diseases
- Parathyroid Disorders and Treatments
- Cardiovascular Issues in Pregnancy
- Cardiac Fibrosis and Remodeling
- Cardiovascular Health and Risk Factors
- Protease and Inhibitor Mechanisms
- Mechanical Circulatory Support Devices
- Hemodynamic Monitoring and Therapy
- Cardiac Valve Diseases and Treatments
- Viral Infections and Immunology Research
- Cell death mechanisms and regulation
- Photonic Crystal and Fiber Optics
Peking University
2014-2024
Peking University First Hospital
2014-2024
Haukeland University Hospital
2018-2023
Peking University Cancer Hospital
2020
University of Bergen
2018
Otto-von-Guericke University Magdeburg
2018
University Hospital Brno
2012
University Hospital Kralovske Vinohrady
2012
General University Hospital in Prague
2012
Central University Hospital of Asturias
2012
<b>Background:</b> Severe acute respiratory syndrome (SARS) was diagnosed in Hong Kong over 1700 patients between March and early June 2003. <b>Methods:</b> 115 with SARS were admitted to Queen Elizabeth Hospital, a large regional hospital Kong, from 2003, of whom 100 either discharged or dead at 31 May. The prospectively studied after admission assess their short term outcomes the risk factors associated adverse outcomes, defined as death need for mechanical ventilation <b>Results:</b> At...
Resistin, a novel adipocytokine, has been suggested as representing link between metabolic signals, inflammation and atherosclerosis. The aim of the present study was to investigate alteration in level plasma resistin patients with acute coronary syndrome (ACS) uncover role resistin.The 39 ACS 26 age-matched healthy subjects this cross-sectional were investigated. Plasma levels measured using radioimmunoassay. significantly increased at 24 h after symptoms onset remained high for 1 week,...
Fibroblast growth factor 21 (FGF21) has been described as a metabolic hormone critical for glucose and lipid metabolism. Previously, high levels of FGF21 were observed in patients with coronary heart disease non-acute myocardial infarction (non-AMI). In this study, we investigated the changes Chinese AMI.We used ELISA to measure circulating 55 AMI 45 non-AMI control on 1st day after syndrome onset. All followed-up within 30 days. significantly higher than those controls (0.25 (0.16-0.34) vs....
Background: The adventitia plays an important role in and is considered to be the initiating site for vascular remodeling. Urotensin II (UII) angiotensin (Ang II) are two most peptides involved remodeling adventitia. Nevertheless, little known about their effect on expression of endothelial growth factor (VEGF). It was hypothesized that both UII Ang could induce VEGF adventitial fibroblasts may play a cell proliferation collagen I synthesis induced by or II. Methods Results: Growth-arrested...
Abstract Aims Endogenous catecholamine release‐inhibitory peptide catestatin has been associated with heart failure (HF). This subgroup analysis of our cohort HF compared the different effects as a predictor for cardiac outcomes in patients reduced (HFrEF), mildly (HFmrEF) or preserved (HFpEF) ejection fraction. Methods Plasma was measured patient 228 cases whole spectrum The deaths were analysed according to prespecified subgroups. Results Over median follow‐up 52.5 months, association...
The real-world usage of intra-aortic balloon pump (IABP) in various cardiogenic shocks (CS) and the association with outcomes are lacking. We aimed to investigate IABP adoption CS a nationwide registry China.We retrospectively retrieved data 30 106 patients (age 67.1 ± 14.6 years, 37.6% female patients) Hospital Quality Monitoring System from 2013 2016. Ischaemic heart disease was leading cause (73.9%). Hypertension, cardiomyopathy, myocarditis, valvular, congenital were seen 36.0%, 7.5%,...
The Chiari networks are reticulated fibers of embryological remnant venous valves in the right atrium. In patients with this congenital variation, manipulation diagnostic catheters can be difficult, and there is a substantial risk entrapment during electrophysiological studies. We report case successful retraction catheter entangled network use lead extraction tool scheduled atrial fibrillation ablation. Rescheduled cryoablation was performed without complication provided good outcome.
Abstracts Background This study aimed to clarify the interrelationship and additive effects of contact force (CF), power application time in both conventional high-power short-duration (HPSD) settings. Methods Among 38 patients with paroxysmal atrial fibrillation who underwent first-time pulmonary vein isolation, 787 ablation points were collected at beginning procedure separate sites. Energy was applied for 60 s under outputs 25, 30 or 35 W (conventional group), 10 when using 50 (HPSD...
Introduction Non-macroreentrant atrial tachycardia (nAT) following fibrillation (AF) ablation is being increasingly reported. Many issues remain to be elucidated. We aimed characterize the fractionated potentials (FPs) in nAT and introduce a new method of cross-mapping for clarifying their roles. Methods Results Forty-four nATs 37 patients were enrolled classified into focal AT (FAT, 12), microreentrant (MAT, 14), small-loop-reentrant (SAT, 18) groups, according activation pattern. FP was...
Abstract In patients with preserved ejection fraction or right bundle branch block (RBBB) pattern requiring a high percentage of ventricular pacing, His‐bundle pacing (HBP) might be an alternative to biventricular although the threshold occasionally occurs. We provided case intrinsic RBBB correction by capturing intra‐Hisian left (LBB) distal different output settings. LBB had advantage much lower while remained most synchrony as HBP. promisingly safe and effective procedure for high‐grade...
Background: Atrial fibrillation (AF) might lead to adverse cardiac consequences. The association between AF burden and prognosis is unknown. Methods Results: This retrospective cohort study enrolled 204 patients (117 males; age 74.5 ± 11.5 years) who underwent dual-chamber pacemaker implantation in our center from October 2003 May 2017. During a median follow-up of 66.5 months, could be detected 153 (75%) the patients. Primary endpoint events (composite readmission, stroke or systemic...
Treatment decisions in patients undergoing non-cardiac surgery are based on clinical assessment. The Revised Cardiac Risk Index (RCRI) is pragmatic and widely used but has only moderate discrimination. We aimed to test the efficacy of CHA2DS2-VASc score combination RCRI predict perioperative risks for surgery.This pre-specified analysis was performed a retrospective cohort intra-abdominal our center from July 1st, 2007 June 30th, 2008. possible association between baseline characteristics...
<h3>Objectives</h3> Arrhythmia associated with acute coronary syndrome is a common phenomenon. Careful investigation on its occurrence and risk factors in this progressed clinical scenery may lead to further standardisation of therapy improvement prognosis. Thus we retrospectively analysed the year-round data our centre attempted provide more information. <h3>Methods</h3> Patients admitted final diagnose as from January 2007 December were enrolled consecutively analysed. <h3>Results</h3> 1....
Objective Perioperative cardiovascular events constitute the majority of complications in noncardiac surgery. Older and female patients have been less investigated. We aimed to evaluate differences perioperative outcomes by age sex. Methods enrolled 1079 (57.5 ± 17.0 years, 42.6% women) undergoing intra-abdominal surgery from July 2007 June 2008 compared occurrence cardiac (≥65 vs. <65 years) Multivariable logistic regression was used investigate associations between age, sex, outcomes....
ABSTRACT Objective Cardiac hypertrophy is the heart’s response to a variety of extrinsic and intrinsic stimuli, some which might finally lead up maladaptive state. Clinical evidence, in vitro vivo studies have implicated urotensin II (U-II/UTS2) development cardiac hypertrophy, contributing (patho)-physiological regulation cardiovascular homeostasis humans. Several genes are associated with left ventricular hypertrophy; considering these, our objective was evaluate possible role UTS2 gene...
Key Teaching Points•Although typical atrial flutter is the predominant form of macroreentrant tachycardia in patients without history cardiac intervention, rare complicated situations such as present dual-loop biatrial may be observed.•Even when counterclockwise rotation around tricuspid annulus right atrium has been demonstrated, cautious observation activation sequence both atria still critical to discover unusual complex situation.•Detailed mapping with a 3-dimensional system helpful...
While pacing has been used for long QT syndrome (LQTs), the optimal modality is controversial.We report a woman with bradycardia and recently implanted single-chamber pacemaker experienced multiple syncope. No device dysfunction was found. Multiple Torsade de Pointes (TdP) induced by bigeminy result from retrograde ventriculoatrial (VA) activation in VVI were demonstrated scenario of previously unidentified LQTs. Replacement dual-chamber ICD intentional atrial eliminated VA conduction...