A5050417245- Covalent Organic Framework Applications
- Supramolecular Chemistry and Complexes
- Polymer composites and self-healing
- Luminescence and Fluorescent Materials
- Metal-Organic Frameworks: Synthesis and Applications
- Conducting polymers and applications
- Cancer-related gene regulation
- Supramolecular Self-Assembly in Materials
- RNA modifications and cancer
- Electrocatalysts for Energy Conversion
- Carbon dioxide utilization in catalysis
- Crystallization and Solubility Studies
- Fuel Cells and Related Materials
- Synthetic Organic Chemistry Methods
- biodegradable polymer synthesis and properties
- X-ray Diffraction in Crystallography
- Porphyrin and Phthalocyanine Chemistry
- Nanopore and Nanochannel Transport Studies
- Advanced Sensor and Energy Harvesting Materials
- Fiber-reinforced polymer composites
- Radiopharmaceutical Chemistry and Applications
- Inflammasome and immune disorders
- Bone and Joint Diseases
- Circular RNAs in diseases
- Bone Metabolism and Diseases
University of Colorado Boulder
2021-2025
Collaborative Innovation Center of Chemistry for Energy Materials
2024
Xiamen University
2024
Jinhua Polytechnic
2024
Sun Yat-sen University
2024
Second Xiangya Hospital of Central South University
2021-2023
Central South University
2021-2023
Biocon (Switzerland)
2023
Wuhan University of Technology
2022
Guangxi Medical University
2017
Covalent adaptable networks (CANs) represent a novel class of polymeric materials crosslinked by dynamic covalent bonds. Since their first discovery, CANs have attracted great attention due to high mechanical strength and stability like conventional thermosets under service conditions easy reprocessability thermoplastics certain external stimuli. Here, we report the example ionic (ICANs), type ionomers, consisting negatively charged backbone structures. More specifically, two ICANs with...
Crystalline materials with uniform molecular-sized pores are desirable for a broad range of applications, such as sensors, catalysis, and separations. However, it is challenging to tune the pore size single material continuously reversibly distinguish small molecules (below 4 angstroms). We synthesized series ionic covalent organic frameworks using tetraphenoxyborate linkage that maintains meticulous synergy between structural rigidity local flexibility achieve continuous reversible (100...
We report, for the first time, highly crystalline cyanurate-linked covalent organic frameworks synthesized via dynamic nucleophilic aromatic substitution. The high crystallinity is enabled by bond exchange reaction (self-correction) between 2,4,6-triphenoxy-1,3,5-triazine and diphenols reversible SNAr catalyzed triazabicyclodecene. CN-COFs contain flexible backbones that exhibit a unique AA'-stacking due to interlayer hydrogen bonding interactions. isoreticular expansion study demonstrates...
Phthalocyanine (Pc), an electro-redox active moiety, has many attractive properties stemming from its large aromatic system and ability to act as a catalyst in electrochemical reactions, such the CO2 reduction reaction (CO2RR). However, due synthetic challenge related geometric requirements poor solubility (strong aggregation), discrete shape-persistent cages consisting of site-isolated, readily accessible Pc moieties have not been available. Here, we report synthesis Zn- Ni-metallated...
The design and development of intricate artificial architectures have been pursued for decades. Helical covalent polymer (HCP) was recently reported as an unexpected topology that consists chiral 1D polymers assembled through weak hydrogen bonds from achiral building blocks. However, many questions remained about the formation, driving force, single-handedness observed in each crystal. In this work, we reveal a metastable, racemic, fully covalently cross-linked, 3D organic framework (COF)...
Abstract Naturally occurring polymeric structures often consist of 1D polymer chains intricately folded and entwined through non‐covalent bonds, adopting precise topologies crucial for their functionality. The exploration crystalline polymers dynamic covalent chemistry (DCvC) supramolecular interactions represents a novel approach developing polymers. This study shows that sub‐angstrom differences in the counter‐ion size can lead to various helical (HCP) topologies, including...
Abstract Thermosets are well known for their advantages such as high stability and chemical resistance. However, developing sustainable thermosets with degradability recyclability faces several principal challenges, including reconciling the desired characteristics during service recycling reprocessing properties required at end of life, establishing efficient methods large‐scale synthesis, aligning current manufacturing process. Here a general strategy is presented on‐demand degradation...
Open AccessCCS ChemistryCOMMUNICATION1 Dec 2021Helical Covalent Polymers with Unidirectional Ion Channels as Single Lithium-Ion Conducting Electrolytes Yiming Hu, Nathan Dunlap, Hai Long, Hongxuan Chen, Lacey J. Wayment, Michael Ortiz, Yinghua Jin, Abdulrahiman Nijamudheen, Jose L. Mendoza-Cortes, Se-hee Lee and Wei Zhang Hu Department of Chemistry, University Colorado Boulder, CO 80309 , Dunlap Mechanical Engineering, Long National Renewable Energy Laboratory, Golden, 80401 Chen Wayment...
Dynamic covalent chemistry (DCvC) has become an important tool in developing smart materials the past few decades. By incorporating reversible bonds into crosslinked polymer networks, those features that are highly desired wearable electronics, such as stretchability, malleability, self-healing capability, and closed-loop recyclability, could be achieved. In this perspective, we briefly summarize how DCvC influences development of dynamic networks discuss their applications electronics. The...
Self-sorting is commonly observed in complex reaction systems, which has been utilized to guide the formation of single major by-design molecules. However, most studies have focused on non-covalent and using self-sorting achieve covalently bonded architectures still relatively less explored. Herein, we first demonstrated dynamic nature spiroborate linkage systematically studied behavior transformation between spiroborate-linked well-defined polymeric molecular architectures, enabled by bond...
Host-guest chemistry, a pivotal branch of supramolecular plays an essential role in understanding and constructing complex structures through non-covalent interactions. Organic molecular cages, characterized by their intrinsic confined cavities, can selectively bind variety guest molecules. Their host-guest chemistry has been well studied the solution phase, several attempts have made to encode well-defined architectures into solid-state polymeric materials. However, only limited studies...
Emerging evidence has linked the dysregulation of N6-methyladenosine (m6A) modification to inflammation and inflammatory diseases, but underlying mechanism still needs investigation. Here, we found that high levels m6A in a variety hyperinflammatory states are p65-dependent because Wilms tumor 1–associated protein (WTAP), key component "writer" complex, is transcriptionally regulated by p65, its overexpression can lead increased modification. Mechanistically, upregulated WTAP more prone...
Within the past two decades, covalent adaptable networks (CANs) have emerged as a novel class of dynamically crosslinked polymers, combining benefits thermosets and thermoplastics. Although some CANs with charged side chains been reported, negatively backbones remain very limited. The integration permanent charge into upon their formation could open up important new applications. Here, we introduce series aliphatic spiroborate‐linked ionic (ICANs), representing category dynamic ionomer...
Within the past two decades, covalent adaptable networks (CANs) have emerged as a novel class of dynamically crosslinked polymers, combining benefits thermosets and thermoplastics. Although some CANs with charged side chains been reported, negatively backbones remain very limited. The integration permanent charge into upon their formation could open up important new applications. Here, we introduce series aliphatic spiroborate‐linked ionic (ICANs), representing category dynamic ionomer...
Abstract Metal-nitrogen co-doped composite (M-N-C) carbon materials exhibit outstanding catalytic performance in oxygen reduction reactions (ORR), making them promising candidates to replace commercial Pt/C catalysts. However, it remains a challenge achieve rational design that ensures uniform dispersion of the metal active centers nitrogen-doped and an effective construction M-N sites enhance ORR performance. This research introduces innovative in-situ pyrolysis technique utilizing guanine...
Abstract The high‐strength and lightweight carbon fiber‐reinforced composites are widely used in various industries. Fused Filament Fabrication (FFF), the most cost‐effective Additive Manufacturing (AM) technology, has gained significant application advantages industry. objective of this study is to improve toughness polyamide for FFF. In work, HDPE was selected reduce hygroscopicity PA6 while lowering cost, fiber introduced reinforce PA6/HDPE blend. elastomer POE‐g‐MAH applied increase as...