A5045350530- Respiratory viral infections research
- Neonatal Respiratory Health Research
- Viral Infections and Vectors
- Influenza Virus Research Studies
- Vaccine Coverage and Hesitancy
- Parvovirus B19 Infection Studies
- Pneumonia and Respiratory Infections
- COVID-19 Impact on Reproduction
- Tracheal and airway disorders
- Viral gastroenteritis research and epidemiology
- Child and Adolescent Health
- Adolescent and Pediatric Healthcare
- Congenital Diaphragmatic Hernia Studies
- Pregnancy and Medication Impact
- Congenital Heart Disease Studies
- Emergency and Acute Care Studies
Wilhelmina Children's Hospital
2021-2025
University Medical Center Utrecht
2020-2025
Respiratory syncytial virus (RSV) is a major cause of mortality in children younger than 5 years worldwide. Systematic reviews have shown that Down syndrome (DS) an independent risk factor for severe RSV infection. We aimed to describe demographic and clinical characteristics with DS who died
BackgroundThe implementation of the approved respiratory syncytial virus (RSV) preventive interventions in immunisation programmes is advancing rapidly. Insight into healthcare costs RSV-related paediatric intensive care unit (PICU) admissions lacking, but great importance to evaluate impact implementation. Therefore, this study aimed determine total annual Netherlands.MethodsA nationwide prospective, observational, multicenter was performed from September 2021 until June 2023. The on PICUs...
Background: Worldwide, respiratory syncytial virus (RSV) is the leading cause of lower tract infections during infancy. Approximately 5% hospitalized infants require pediatric intensive care unit (PICU) admission. Our objective was to capture a complete overview PICU admission, including yet unseen burden, understand full clinical impact new preventive interventions. Methods: A nationwide, prospective, observational, multicenter study performed in Netherlands. Patients included <12 months...
Background: We aimed to evaluate the cost-effectiveness of prophylactic interventions against RSV in infants nearing licensure, for six European countries.Methods: used a static cohort model compare costs and health effects four intervention programs no program each other: year-round maternal immunization (MI), monoclonal antibody (mAb), seasonal mAb (October April), plus catch-up October. Input parameters were obtained from national registries literature. Influential input identified with...