A5053266227- Vector-borne infectious diseases
- SARS-CoV-2 and COVID-19 Research
- Vaccine Coverage and Hesitancy
- Mosquito-borne diseases and control
- Viral Infections and Vectors
- Bacterial Infections and Vaccines
Russian Academy of Sciences
2022
Lomonosov Moscow State University
2021
Chumakov Institute of Poliomyelitis and Viral Encephalitides
2021
Although unprecedented efforts aiming to stop the COVID-19 pandemic have been made over past two years, SARSCoV-2 virus still continues cause intolerable health and economical losses. Vaccines are considered most effective way prevent infectious diseases, which has reaffirmed for COVID-19. However, in context of continuing spread because insufficient vaccination coverage emergence new variants concern, there is a high demand strategy amendment. The ability elicit protective immunity at entry...
Tick-borne encephalitis virus (TBEV), a member of the genus Flavivirus, is common in Europe and Asia causes severe disease central nervous system. A promising approach development therapy for TBEV infection search small molecule antivirals targeting flavivirus envelope protein E, particularly its β-n-octyl-d-glucoside binding pocket (β-OG pocket). However, experimental studies candidate may be complicated by varying amounts different forms E samples. Viral particles with conformations...