- Advanced Photocatalysis Techniques
- Crystallization and Solubility Studies
- X-ray Diffraction in Crystallography
- Copper-based nanomaterials and applications
- Nanoparticle-Based Drug Delivery
- Nanoplatforms for cancer theranostics
- Gas Sensing Nanomaterials and Sensors
- Advanced battery technologies research
- Catalytic Processes in Materials Science
- Electrochemical Analysis and Applications
- Advanced Nanomaterials in Catalysis
- Magnetic Properties and Applications
- Advanced Fiber Optic Sensors
- Electric Motor Design and Analysis
- TiO2 Photocatalysis and Solar Cells
- Pancreatic function and diabetes
- Management Theory and Practice
- Photonic and Optical Devices
- Perovskite Materials and Applications
- Electrocatalysts for Energy Conversion
- Nanomaterials for catalytic reactions
- Advanced Sensor and Control Systems
- Magnetic Bearings and Levitation Dynamics
- Microbial Fuel Cells and Bioremediation
- Microbial Natural Products and Biosynthesis
Third Xiangya Hospital
2024-2025
Central South University
2024-2025
Xiangya Hospital Central South University
2024-2025
Krirk University
2023-2024
Tsinghua University
1996-2024
Fuzhou University
2015-2024
Sanming University
2009-2024
Fujian University of Technology
2022
Chongqing Medical University
2012-2021
Changsha University
2002-2020
Efficient accumulation and intracellular drug release in cancer cells remain a crucial challenge developing ideal anticancer delivery systems. Here, poly(N-isopropylacrylamide)-ss-acrylic acid (P(NIPAM-ss-AA)) nanogels based on NIPAM AA cross-linked by N,N'-bis(acryloyl)cystamine (BAC) were constructed precipitation polymerization. The exhibited pH/redox dual responsive doxorubicin (DOX) behavior vitro tumor cells, which DOX from was accelerated lysosomal pH (pH 4.5) cytosolic reduction (10...
Reconciling the conflicting needs for a prolonged circulation time, enhanced cellular uptake by bulk tumor cells and cancer stem (CSCs), extensive tissue penetration remains major challenge current nano drug delivery systems. Here we describe smart poly(N-isopropylacrylamide)-based nanogels with fast adaptive hydrophobicity to solve these contradictory requirements chemotherapy. The are hydrophilic in blood prolong their time. Once they accumulate at sites, rapidly become hydrophobic...
Abstract Herein, we reported a octahedral Cd 3 (C N S ) 2 coordination polymer as new noble metal-free photocatalyst for robust photocatalytic H O production from methanol/water solution. The can give an unprecedented yield of ca. 110.0 mmol • L −1 g at pH = 2.8 under visible light illumination. characterization results clearly revealed that the proceeds by pathway two-electron reduction on catalyst surface. This work showed potential perspective M x y (M transitional metals) polymers series...
Effective charge separation and migration pose a critical challenge in the field of solar-driven hydrogen production. In this work, Z-scheme structured CuInS2/ZnIn2S4 heterojunction was successfully fabricated through two-step hydrothermal synthesis method to significantly enhance efficiency solar-to-hydrogen energy conversion. Structural characterization revealed that lattice-matched exhibits an enlarged interfacial contact area, which facilitates transfer photogenerated charges....
The microbial fuel cell (MFC), acknowledged as an innovative bioenergy conversion system, has attracted considerable attention in research. An MFC is a device that utilizes microorganisms to directly convert chemical energy present organic compounds into electrical energy. This bioelectrochemical hybrid system functions not only power generation tool but also effective instrument for sewage treatment, incorporating nutrient recovery. Its noteworthy advantages encompass conservation, sludge...
The enantioselective hydrogenation of a series challenging substrates, alpha-aryl-beta-substituted acrylic acids, was realized with high efficiency and enantioselectivity (up to 96%) under the catalysis Ir(i) complex Spiro-based P,N ligand, SpinPHOX.
Ideal anticancer nano drug delivery systems (NDDSs) need to overcome a series of physiological barriers including blood circulation, tumor accumulation, penetration, internalization by cancer cells, lysosomal escape, and on-demand intracellular release following systemic administration. However, it remains big challenge construct NDDSs that can all the at same time. Here, we develop zwitterionic temperature/redox-sensitive nanogels loaded with near-infrared (NIR) dye Indocyanine green (ICG)...
The impurity [Fe<sup>3+</sup>–O<sup>2−</sup>] species in HZSM-5 zeolite is predominantly tetrahedrally coordinated and the photoactive centre for photocatalytic CO<sub>2</sub> conversion.
Improving the intratumoral distribution of anticancer agents remains critical challenge for developing efficient cancer chemotherapy. Luminescent porous silicon nanoparticles (PSiNPs) have attracted considerable attention in biomedical field especially drug delivery. Here, we described lysosomal exocytosis-mediated domino-like intercellular delivery undecylenic acid-conjugated PSiNPs (UA-PSiNPs) deep tumor penetration. UA-PSiNPs with significantly improved stability physiological conditions...
This work maps the distribution of HER onset potential, screens electrodeposition parameters, and optimizes them to achieve better performance.
Explore the clinical value of various complete blood count (CBC)-derived inflammation indicators to predict in-hospital mortality in patients with extensive burns. Systemic indexes, including lymphocyte platelet ratio (LPR), neutrophil-to-lymphocyte (NLR), neutrophil-to-monocyte (NMR), monocyte-to-lymphocyte (MLR), * (NLPR), systemic index (SII), and response (SIRI) on days 1, 3, 7 after admission were calculated 135 We included burns, 97 survivors 38 non-survivors. After adjusting for...
Sodium hydroxide (NaOH) is known to cause severe injuries through lipid saponification; however, the mechanisms underlying NaOH-induced skin injuries, particularly their effects on metabolism and ferroptosis, are unclear. Here, we aimed elucidate these based profile evaluations ferroptosis occurrence. We used experimental rat models of burns (skin exposed 0.05% NaOH for 90 or 180 s) alongside a sham-treated control group. Skin morphology integrity were assessed. Differentially expressed...
Total synthesis of natural product marmycin A was studied. An expeditious synthetic strategy for the key fragment 8-amino-3-methylbenz[a]anthraquinone (1) established with decarboxylative alkylation, Pd(OAc)2-catalyzed cyclization, aromatization, and C−N coupling as steps. However, final assembly hampered by failure to obtain carbohydrate 2. Instead, a small library desmethyl analogues prepared in moderate yields using InBr3-catalyzed C- N-glycosidation reaction. The absolute configuration...
To improve the magnetic properties and MRI contrast effect of Fe3O4 superparamagnetic nanoparticles (NPs), a series oleate-capped, Mn-doped MnxFe(1−x)Fe2O4 (x ≤ 0.4) NPs was prepared via thermal decomposition method subsequently assembled into nanoclusters by carboxylic silane. The effects Mn doping clustering on magnetization, relaxivity enhancement were studied. Our results revealed that exhibited highest saturation magnetization 82.55 emu g−1 when x = 0.05. Correspondingly,...
Catalysis is the most efficient and economical method for treating volatile organic pollutants (VOCs). Among many materials that are used in engineering, platinized carbon nitride (Pt/g-C3N4) an multifunctional catalyst which has strong light absorption mass transfer capabilities, enable it to be photocatalysis, thermal catalysis photothermal synergistic degradation of benzene. In this work, Pt/g-C3N4 was prepared by four precursors catalytic benzene, show different activities, tests were...
This study focuses on the development of heterojunction photocatalysts for efficient utilization solar energy to address crisis and reduce environmental pollution. Cadmium sulfide (CdS)/graphite-type carbon nitride (g-C3N4) nanocomposites were synthesized using a hydrothermal method, their photoelectrochemical properties photocatalytic performance hydrogen evolution reaction (HER) characterized. Scanning electron microscope images showed intimate interface caviar-like nanoheterojunction CdS...