- Neuroscience and Neuropharmacology Research
- Neurogenesis and neuroplasticity mechanisms
- Memory and Neural Mechanisms
- Sleep and Wakefulness Research
- Stress Responses and Cortisol
- Tryptophan and brain disorders
- Neurotransmitter Receptor Influence on Behavior
- Alzheimer's disease research and treatments
- Circadian rhythm and melatonin
- Traumatic Brain Injury and Neurovascular Disturbances
- Tea Polyphenols and Effects
- Cholinesterase and Neurodegenerative Diseases
- Neuroinflammation and Neurodegeneration Mechanisms
- SARS-CoV-2 and COVID-19 Research
- Pharmacological Effects and Toxicity Studies
- Forensic Toxicology and Drug Analysis
- Anesthesia and Neurotoxicity Research
- COVID-19 Clinical Research Studies
- Cancer-related cognitive impairment studies
- Adipose Tissue and Metabolism
- Medicinal Plants and Neuroprotection
- Parasites and Host Interactions
- Histone Deacetylase Inhibitors Research
- COVID-19 diagnosis using AI
- Synthesis and bioactivity of alkaloids
Mashhad University of Medical Sciences
2015-2025
Weatherford College
2024
Kerman University of Medical Sciences
2011-2015
Otto-von-Guericke University Magdeburg
2015
University of Bojnord
2014
Tabriz University of Medical Sciences
2009
As one of the most studied protein hormones, insulin as well its receptor have been known to play key roles in a variety important biological processes. Detection and central nervous system (CNS) has led rapidly growing interest effects insulin. Insulin are located specific area CNS with diversity region-specific functions different from direct carbohydrate homeostasis periphery. The high density insulin/insulin brain areas such hippocampus cerebral cortex shown an role higher cognitive...
We have elucidated the alteration in hippocampal and cerebellum function following chronic cisplatin treatment male female rats. Hippocampus related behavioral dysfunction cisplatin-treated [intraperitoneally, 5 mg/(kg/week) for weeks from 23-day-old] rats were analyzed using explorative, motor function, learning, memory tasks (grasping, rotarod, open field, Morris water maze tests). Exposure to impaired coordination was reflected by a decrease grasping time compared vehicle-treated controls...
The weight of evidence suggests that sleep is essential for the processes memory consolidation and deprivation (SD) impairs retention long-term in both humans experimental animals, which associated with oxidative stress damage within brain. Green tea polyphenols have revealed carcinogenic, antioxidant, anti-, anti-mutagenic properties. We aimed to investigate possible protective effect green extract (GTE) its main active catechin, epigallocatechin-3-gallate (EGCG), on post-training total...
While traumatic brain injury (TBI) is a predisposing factor for development of post-traumatic epilepsy (PTE), the occurrence seizures following trauma can infuriate adverse consequences injury. However, effect in epileptogenesis after mild TBI cannot yet be accurately confirmed. This study was designed to investigate histopathological and molecular modifications induced by on traumatized brain.Using new method, head were evoked sub-convulsive dose pentylenetetrazole (PTZ) fifteen days...
Exercise (Ex) and environmental enrichment (EE) as the nondrug solutions have positive effects on cognitive behaviors also increase ability to cope with anxiety, fear, stress. In this research, we decided investigate simultaneous effect of Ex EE anxiety-like hippocampal neurogenesis markers in healthy rats. A total 40 male Wistar rats were divided into four treatment groups: control, EE, Ex, + Ex. Animals groups housed large cages (50 × 50 cm) equipped toys objects different shapes for 3...
Background: Methamphetamine (METH) as a synthetic psychostimulant is being increasingly recognized worldwide problem, which may induce memory impairment. On the other hand, it well established that naloxone, an opiate antagonist, has some beneficial effects on learning and memory. The present research aimed at evaluating naloxone spatial impairment triggered by neurotoxic regimen of METH in male rats. Materials Methods: animals received subcutaneous (sc) (4×6 mg/kg 2-h intervals),...
Methamphetamine (METH) as a synthetic psychostimulant is being increasingly recognized worldwide problem, which may induce memory impairment. On the other hand, it well established that naloxone, an opiate antagonist, has some beneficial effects on learning and memory. The present research aimed at evaluating naloxone spatial impairment triggered by neurotoxic regimen of METH in male rats.
Introduction: New neurons are constantly created in specific areas of the adult brain and functionally integrated into neuronal networks. Neural stem cells exist microenvironments called cell niches. It has been shown that neurotransmitters provide vital components niche signals modulate several aspects neurogenesis. demonstrated changes neurotransmitter signaling may influence Further works required to clarify how pathways control Conclusion: In this review, we discuss regulates development...