Li Li

ORCID: 0000-0003-4101-3759
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About
Contact & Profiles
Research Areas
  • Physiological and biochemical adaptations
  • Aquaculture Nutrition and Growth
  • Marine Bivalve and Aquaculture Studies
  • Environmental Toxicology and Ecotoxicology
  • Environmental Quality and Pollution
  • Botany and Plant Ecology Studies
  • Metabolomics and Mass Spectrometry Studies
  • Meat and Animal Product Quality
  • Reproductive biology and impacts on aquatic species
  • Wildlife-Road Interactions and Conservation
  • Adipose Tissue and Metabolism
  • Genetic diversity and population structure
  • Peatlands and Wetlands Ecology
  • Polar Research and Ecology
  • Animal Ecology and Behavior Studies
  • Aquaculture disease management and microbiota
  • Evaluation Methods in Various Fields
  • Ecology and Vegetation Dynamics Studies
  • Primate Behavior and Ecology
  • Aquatic life and conservation
  • Wildlife Ecology and Conservation
  • Biochemical effects in animals
  • Fish Ecology and Management Studies
  • Invertebrate Immune Response Mechanisms
  • Evaluation and Optimization Models

Marine Biology Institute of Shandong Province
2015-2025

Second People’s Hospital of Huai’an
2024

Institute of Hydrobiology
2024

Chinese Academy of Sciences
2014-2024

Shanghai Jiao Tong University
2015-2024

Xuzhou Medical College
2024

Institute of Oceanology
2014-2023

University of Chinese Academy of Sciences
2023

Ocean University of China
2018

Qingdao National Laboratory for Marine Science and Technology
2018

Background: Cancer-Associated Fibroblasts (CAFs) constitute a heterogeneous group of cells critical for the remodeling tumor microenvironment (TME). Given their significant impact on progression, particularly in skin cancers, deeper understanding characteristics and functions is essential. Methods: This study employed single-cell transcriptomic analysis to explore diversity CAFs within three major types cancer: basal cell carcinoma, melanoma, head neck squamous carcinoma. We applied...

10.2174/0115665232331353240911080642 article EN Current Gene Therapy 2024-09-25

Abstract Fat greenling ( Hexagrammos otakii Jordan & Starks, 1895) is a valuable marine fish species, crucial for aquaculture in Northern China due to its high-quality meat and significant economic value. However, the industry faces challenges such as trait degradation, early sexual maturity, disease susceptibility, necessitating advanced genomic interventions sustainable cultivation. This study presents first chromosomal-level genome assembly of H. , achieved using PacBio long-read...

10.1038/s41597-025-04368-3 article EN cc-by Scientific Data 2025-01-15

Salinity is an important ecological factor that impacts the growth and survival of aquatic organisms. The salinity seawater in coastal estuarine areas often subject to dynamic changes because seasonal rainfall continental runoff. Thus, current study investigated effects sudden on rate osmotic pressure regulation mechanisms bottom-sowing seedlings economically ark shell, Scapharca subcrenata. By simulating occur after rainstorms, results showed hemolymph Na+, K+, Ca2+, Cl- concentrations...

10.3389/fphys.2020.00884 article EN cc-by Frontiers in Physiology 2020-07-17

Abstract Background and Objectives Previous studies have suggested that the aberrant expression of Stanniocalcin‐1 (STC1) occurs in tumor cells. In this study, we explored whether circulating STC1 mRNA is a promising biomarker peripheral blood patients with non‐small cell lung cancer (NSCLC). Methods The level was determined sensitive quantitative real‐time reverse transcription PCR assay. data were analyzed by statistical methods one‐way ANOVA, Mann–Whitney–Wilcoxon U‐Test, Receiver...

10.1002/jso.21948 article EN Journal of Surgical Oncology 2011-06-07

Stanniocalcin 1 (STC1) is reported to functionally participate in the development of several cancers. However, role STC1 tumorigenesis and progression lung adenocarcinoma remains be fully elucidated. Here, we found that average levels serum were 5.47, 5.53, 6.94 ng/mL (P = 0.0045) healthy subjects patients with at tumor stages I-II III-IV according Union for International Cancer Control (UICC), respectively. Subsequently, positive correlation between expression level tissues was confirmed by...

10.1007/s13277-015-4431-x article EN Tumor Biology 2015-11-17

The northern bay scallop Argopecten irradians (Lamarck) and the southern concentricus (Say) were introduced into China in 1980s 1990s, are now major aquaculture molluscs China. Here, we report transcriptome sequencing of two subspecies subsequent association analysis on candidate gene trait heat tolerance. In total, RNA from six tissues 67 42 individuals scallops, respectively, used 55.5 34.9 million raw reads generated, respectively. There 82,267 unigenes produced which 32,595 annotated....

10.1371/journal.pone.0104960 article EN cc-by PLoS ONE 2014-08-14

Two approaches (i.e. water and dry or semi-dry transport) have been developed for the transport of swimming crabs Portunus trituberculatus in recent years. To evaluate their differential effects on physiological responses crabs, we measured haemolymph components (metabolic substrates, metabolites ions) hepatopancreas glycogen level at different time intervals after exposure to thermal stresses air. The immersed exhibited no significant change all metabolic substrates except glucose...

10.1111/are.12752 article EN Aquaculture Research 2015-04-02

Abstract In this experiment, the effects of a sudden drop in salinity on antioxidant defense system and related gene expression ark shell Scapharca subcrenata were examined. The seawater after rainstorm was simulated, subsequently differentially expressed metabolic markers identified by LC-MS non-targeted metabolomics. When dropped to 14‰ (S14), total anti-oxidant content, activity Na + /K -ATPase, superoxide dismutase (SOD), catalase (CAT), content malondialdehyde, levels Mn-SOD , CAT...

10.1038/s41598-020-63293-0 article EN cc-by Scientific Reports 2020-04-30
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