A5029872257- Functional Brain Connectivity Studies
- Schizophrenia research and treatment
- Mental Health Research Topics
- Child and Adolescent Psychosocial and Emotional Development
- Psychosomatic Disorders and Their Treatments
- Autism Spectrum Disorder Research
- Tryptophan and brain disorders
- Psychology of Moral and Emotional Judgment
- Advanced Neuroimaging Techniques and Applications
- Empathy and Medical Education
- Stress Responses and Cortisol
- Mental Health Treatment and Access
- Neural and Behavioral Psychology Studies
- Hallucinations in medical conditions
- Psychopathy, Forensic Psychiatry, Sexual Offending
- Action Observation and Synchronization
- Behavioral Health and Interventions
- Emotional Intelligence and Performance
- Mental Health and Psychiatry
- Bipolar Disorder and Treatment
- Birth, Development, and Health
- Family and Disability Support Research
- Obsessive-Compulsive Spectrum Disorders
- Cognitive Abilities and Testing
- Neuroendocrine regulation and behavior
University of Birmingham
2013-2023
Authorised Association Consortium
2022
Centre for Mental Health
2020
University of Manchester
2009-2013
Institute of Mental Health
2011-2012
University of Nottingham
2009-2012
Nottinghamshire Healthcare NHS Foundation Trust
2012
Abstract Empathy has been inconsistently defined and inadequately measured. This research aimed to produce a new rigorously developed questionnaire. Exploratory (n 1= 640) confirmatory 2= 318) factor analyses were employed develop the Questionnaire of Cognitive Affective (QCAE). Principal components analysis revealed 5 factors (31 items). Confirmatory confirmed this structure in an independent sample. The hypothesized 2-factor (cognitive affective empathy) was tested provided best most...
This study investigated the influence of personality characteristics and gender on adolescents' perception risk their risk-taking behaviour. Male female participants (157 females: 116 males, aged 13-20) completed self-report measures perception, personality. perceived behaviours as less risky, reportedly took more risks, were sensitive to negative outcomes socially anxious than participants. Path analysis identified a model in which age, behavioural inhibition impulsiveness directly...
Immune system dysfunction is hypothesised to contribute structural brain changes through aberrant synaptic pruning in schizophrenia. However, evidence mixed and there a lack of inflammation its effect on grey matter volume (GMV) patients. We that inflammatory subgroups can be identified the will show distinct neuroanatomical neurocognitive profiles. The total sample consisted 1067 participants (chronic patients with schizophrenia n = 467 healthy controls (HCs) 600) from Australia...
Auditory verbal hallucinations (AVH) often lead to distress and functional disability, are frequently associated with psychotic illness. Previously both state trait magnetic resonance imaging (MRI) studies of AVH have identified activity in brain regions involving auditory processing, language, memory areas default mode network (DMN) salience (SN). Current evidence is clouded by research mainly participants on long-term medication, chronic illness choice seed made 'a priori'. Thus, the aim...
Despite growing interest in the beneficial effects of positive touch experiences throughout our lives, and individual differences how these are perceived, there is not yet available a contemporary self-report measure attitudes, for which factor structure has been validated. This article describes four studies carried out during construction validation Touch Experiences Attitudes Questionnaire (TEAQ). The original TEAQ, containing 117 items relating to was systematically constructed....
AbstractThis study used functional magnetic resonance imaging to examine the neural substrates of empathy, Theory Mind (ToM), and self–other differentiation involved in adaptive understanding people's internal states. Three conditions were distinguished both sad neutral (no obvious emotion) contexts. The empathy condition imagining what another person is feeling while more cognitively loaded ToM would make feel better. self-reference required participants imagine how they someone else's...
Disturbance of hypothalamus–pituitary–adrenal axis activity is commonly reported in a range mental disorders blood, saliva and urine samples. This study aimed to look at longer-term cortisol levels their association with clinical symptoms. Hair strands 30 young people (16–25 years) presenting health problems (Mage±SD=21±2.4, 26 females) 28 healthy controls (HC, Mage±SD=20±2.9, were analyzed for concentrations, representing the past 6 months prior hair sampling. Clinical participants...
Abstract Diagnostic heterogeneity within and across psychotic affective disorders challenges accurate treatment selection, particularly in the early stages. Delineation of shared distinct illness features at phenotypic brain levels may inform development more precise differential diagnostic tools. We aimed to identify prototypes depression psychosis investigate their heterogeneity, with common, comorbid transdiagnostic symptoms. Analyzing clinical/neurocognitive grey matter volume (GMV) data...
Approaches are needed to stratify individuals in early psychosis stages beyond positive symptom severity investigate specificity related affective and normative variation validate solutions with premorbid, longitudinal, genetic risk measures.
The presence of peers is suggested to increase risk‐taking behaviour by heightening response reward. current study investigated this using a computerized financial task which was performed twice group young adults ( n = 201, median age 19.8 years): once alone and while in the two peers. An overall observed when with compared CHANGE ). positively associated self‐reported levels reward responsiveness fun seeking older lack perseverance were reduced . association between both resistance...
Empathy is an important concept in psychology and cognitive neuroscience. Despite the controversy around its definition, most researchers would agree that empathy a multidimensional phenomenon which involves vicarious experience of another person's affective state understanding experience. Self-report measures constitute tool for both research clinical practice. The main goal this study was to adapt psychometric properties Questionnaire Cognitive Affective (QCAE), worldwide used measure...
ABSTRACT Telephone helplines have long been recognised to provide an effective way reach individuals in crisis and several advantages of this anonymous form intervention described. Most use volunteers respond calls, including those specifically set up for students. Our study investigates differences the personality traits neuroticism, extroversion openness, conscientiousness agreeableness, empathy as measured using Interpersonal Reactivity Index (IRI) mental health experiences between 54 52...
Risk-taking behaviour and onset of mental illness peak in adolescence young adulthood. This study evaluated the interconnectedness domains risk-taking behaviour, health (symptoms depression social anxiety), psychosocial maturity, risk perception, age, gender a sample 306 adolescents adults. Participants between ages 16 35 completed online self-report measures assessing depressive symptoms, socially anxious maturity perception. Socially perception were directly associated with behaviour....
Most individuals at ultra-high risk (UHR) for psychosis do not transition to frank illness. Nevertheless, many have poor clinical outcomes and impaired psychosocial functioning. This study used voxel-based morphometry investigate if baseline grey white matter brain densities identification as UHR were associated with functional outcome medium- long-term follow-up. Participants help-seeking (n = 109, 54M:55F) who underwent magnetic resonance imaging baseline; was assessed an average of 9.2...