A5057483138- Congenital Heart Disease Studies
- Pulmonary Hypertension Research and Treatments
- Cardiac Structural Anomalies and Repair
- Cardiovascular Function and Risk Factors
- Mechanical Circulatory Support Devices
- Tracheal and airway disorders
- Cardiac Arrhythmias and Treatments
- Renal function and acid-base balance
- Cardiac Arrest and Resuscitation
- Cardiac Valve Diseases and Treatments
- Cardiac pacing and defibrillation studies
- Heart Failure Treatment and Management
- Transplantation: Methods and Outcomes
- Coronary Artery Anomalies
- Cardiovascular Issues in Pregnancy
- Cardiovascular Effects of Exercise
- Takotsubo Cardiomyopathy and Associated Phenomena
- Cardiac Imaging and Diagnostics
- Vascular Anomalies and Treatments
- Kawasaki Disease and Coronary Complications
- Infant Development and Preterm Care
- Cardiac electrophysiology and arrhythmias
- Sepsis Diagnosis and Treatment
- Hemodynamic Monitoring and Therapy
- Cardiovascular and Diving-Related Complications
Stollery Children's Hospital
2019-2025
Cohen Children's Medical Center
2022-2025
University of Alberta
2020-2025
Donald & Barbara Zucker School of Medicine at Hofstra/Northwell
2023-2024
University of Alberta Hospital
2019
Alberta Hospital Edmonton
2019
Cincinnati Children's Hospital Medical Center
2012-2017
Fistula Foundation
2012
Background The Occlutech Atrial Flow Regulator (AFR) is a self-expandable double-disc nitinol device with central fenestration. Its use has been approved in the adult population heart failure and described for pulmonary hypertension (PH). Only case reports small series have published about its paediatric congenital disease (CHD). Objectives authors sought to investigate feasibility, safety, short-term follow-up of AFR implantation patients CHD or children PH cardiomyopathy. Methods This...
<h3>Objectives</h3> Diastolic dysfunction (DD), a key driver of long-term Fontan outcomes, may be concealed during standard haemodynamic evaluation. We sought to identify patients with occult DD using 'ventricular stress testing' rapid volume expansion (RVE). <h3>Methods</h3> Cardiac catheterisation RVE was performed routinely in between 11/2012 and 4/2015. Baseline post-stress data were compared t test, Mann–Whitney U χ<sup>2</sup> Fisher9s exact tests. A ventricular end diastolic pressure...
Introduction Single ventricle diastolic dysfunction and hepatic fibrosis are frequently observed in patients with a Fontan circulation. The relationship between adverse haemodynamics end-organ has not been investigated adolescents young adults Methods Prospective observational study of who had cardiac catheterisation. Cardiac MRI T1 mapping was obtained to measure extracellular volume (ECV), marker myocardial fibrosis. Hepatic magnetic resonance elastography performed assess liver shear...
Background In Fontan circulation, diastolic dysfunction portends a worse clinical outcome but may be concealed during routine assessment. Invasive evaluation with rapid volume expansion (RVE) can identify patients occult (ODD). We sought to evaluate the association between ODD and adverse outcomes at medium-term follow-up. Methods Results conducted single-center observational study of circulation who underwent catheterization RVE from 2012 2017. was defined as post-RVE end-diastolic pressure...
BACKGROUND: Neonates with hypoplastic left heart syndrome variants an intact or highly restrictive atrial septum (HLH-IAS) require immediate postnatal intervention to survive. Emergent decompression (LAD) via a percutaneous hybrid approach is standard, but the comparative effectiveness and outcomes of these approaches remain underexplored. METHODS: A multicenter retrospective analysis all neonates HLH-IAS who underwent LAD in first 36 hours life from January 2009 March 2020 at 14 North...
The clinical deterioration commonly experienced by pediatric patients with pulmonary arterial hypertension (PAH) has motivated a shift in the treatment of (PH) through innovations surgical salvage interventions. Occlutech fenestrated atrial septal defect (FASD) Occluder and flow regulator (AFR), which provides protective, atrial-level shunt during hypertensive crises, have found an important role treating PAH. Other groups PH may also benefit from similar protective physiology. primary aim...
Abstract Acute heart failure related to anaphylactic shock is often reversible and necessitates aggressive support ensure full recovery. We report the case of a 15-year-old boy who developed severe ventricular dysfunction haemodynamic instability after administration amiodarone required temporary mechanical circulatory with left assist device. He had recovery cardiac function returned baseline neurologic status. This first successful device use for from cardiovascular collapse due anaphylaxis.
To describe acute and mid-term outcomes following presentation with, treatment for, life-threatening airway bleeding (hemoptysis) in palliated single ventricle congenital heart disease (SV-CHD).Case series of patients with SV-CHD who presented to a large centre hemoptysis between 2004 2015.Twenty-one episodes occurred 12 (58% female, median 10.5 (IQR 7.2, 16.4) years). First episode after Fontan completion (n=8), superior cavopulmonary anastomosis (SCPA, n=3) one shunt-dependent patient....
Introduction: Systolic flattening of the inter-ventricular septum (IVS) is a marker elevated right ventricular pressure (RVp). It can be non-invasively quantified by left eccentricity index (LVEI), RV to (LV) ratio and novel - systolic angle (SFA). Data evaluating relationship between these indices invasive RVp in pediatrics are limited. Methods: Patients referred for heart cardiac catheterizations (CC) were enrolled underwent echocardiograms after induction anesthesia. The SFA, RV:LV LVEI...
In infants with single-ventricle congenital heart disease, prematurity and low weight at the time of Norwood operation are risk factors for mortality. Reports assessing outcomes (including neurodevelopment) post palliation in ≤2.5 kg limited.All who underwent a Norwood-Sano procedure between 2004 2019 were identified. Infants (cases) matched 3:1 >3.0 (comparisons) year surgery cardiac diagnosis. Demographic perioperative characteristics, survival, functional neurodevelopmental...