A5102980888- Congenital Heart Disease Studies
- Cardiovascular and Diving-Related Complications
- Cardiac Valve Diseases and Treatments
- Cardiac Arrhythmias and Treatments
- Infective Endocarditis Diagnosis and Management
- Aortic Disease and Treatment Approaches
- Pulmonary Hypertension Research and Treatments
- Cardiac tumors and thrombi
- Mechanical Circulatory Support Devices
- Vascular anomalies and interventions
- Renal and Vascular Pathologies
- Coronary Artery Anomalies
- Cardiac Imaging and Diagnostics
- Cardiac electrophysiology and arrhythmias
- Cardiac Structural Anomalies and Repair
- Congenital Diaphragmatic Hernia Studies
- Atrial Fibrillation Management and Outcomes
- Cardiovascular Conditions and Treatments
- Heart Failure Treatment and Management
- Cardiovascular Issues in Pregnancy
- Vascular Anomalies and Treatments
- Neuroendocrine Tumor Research Advances
- Prenatal Substance Exposure Effects
- Coronary Interventions and Diagnostics
- Ion channel regulation and function
Guy's and St Thomas' NHS Foundation Trust
2018-2025
Evelina London Children's Healthcare
2018-2025
St Thomas' Hospital
2019-2025
NewYork–Presbyterian Brooklyn Methodist Hospital
2024
Cornell University
2024
Queen Sirikit National Institute of Child Health
2018
University Malaya Medical Centre
2018
Rangsit University
2018
St. Paul's Hospital
2018
University of Malaya
2018
Covered stent correction of sinus venosus ASDs (SVASD) is a relatively new technique. Challenges include anchoring sufficiently long in nonstenotic superior vena cava (SVC) and expanding the at wider SVC-RA junction without obstructing anomalous right upper pulmonary vein (RUPV). The 10-zig covered Cheatham-platinum (CCP) has advantage being available lengths 5-11 cm dilatable to 34 mm diameter.An international registry reviewed outcomes CCP stents 75 patients aged 11.4-75.9 years (median...
Background The Occlutech Atrial Flow Regulator (AFR) is a self-expandable double-disc nitinol device with central fenestration. Its use has been approved in the adult population heart failure and described for pulmonary hypertension (PH). Only case reports small series have published about its paediatric congenital disease (CHD). Objectives authors sought to investigate feasibility, safety, short-term follow-up of AFR implantation patients CHD or children PH cardiomyopathy. Methods This...
Superior sinus venosus atrial septal defect (SVASD) is commonly associated with partial anomalous pulmonary venous drainage (PAPVD). We aimed to describe the first series of percutaneous SVASD and PAPVD correction using a two-step simulation for procedural planning.Patients right clinical indication were selected. They underwent an ex vivo on 3D-printed model followed by in balloon inflation targeted stent landing zone. The procedure consisted deploying 10-zig custom-made covered SVC-RA...
Newborns with transposition of the great arteries (TGA) are at risk severe hypoxia from inadequate atrial mixing, closure arterial duct and/or pulmonary hypertension (PPHN). Acute maternal hyperoxygenation (AMH) might assist in identifying at-risk fetuses. We report vasoreactivity to AMH TGA fetuses and its relationship early postnatal requirement for emergency balloon septostomy (e-BAS). Standard fetal echocardiographic (FE) assessment foramen ovale (FO): total septal length morphology flap...
Abstract Objectives To highlight the importance of serial echocardiography in preterm infants with bronchopulmonary dysplasia (BPD) to diagnose recurrent pulmonary vein stenosis (PVS) and understand its contribution respiratory deteriorations. Case presentation A female infant born at 23+5 weeks gestation had numerous complications related extreme prematurity, including BPD. She was diagnosed PVS on echocardiogram after experiencing deteriorations hypertensive crises. Initial management...
Abstract Objectives: To assess short- and medium-term outcomes of VenusP-valve implantation in the pulmonary position paediatric population. Background: Percutaneous valve is now an established alternative to surgical replacement, especially those with conduits right ventricular outflow tract. The VenusP-valve™ (Venus Medtech, Shanghai, China) has demonstrated early efficacy adult population larger conduit-free tracts. However, its use children not been well described. Methods: Retrospective...
Abstract Background The superior sinus venosus atrial septal defect is a congenital communication between the left and right atria. Open surgical approach by patch closure has historically been only treatment option. Recently, transcatheter developed. This study aims to compare efficacy safety of in defect. Methods Between March 2010 December 2020, 58 patients (median age: 45.4, range 14.8−73.8) underwent either or correction with partial anomalous pulmonary venous drainage. Results...
BACKGROUND: Covered stent correction for a sinus venosus atrial septal defect (SVASD) was first performed in 2009. This innovative approach initially viewed as experimental and reserved highly selected patients with unusual anatomic variants. In 2016, increasing numbers of procedures began to be performed, several centers, it is now offered standard care option alongside surgical repair. However, covered SVASD not recognized by regulatory authorities, the minds many pediatric adult...
Background Successful anatomic repair of congenitally corrected transposition the great arteries achieves excellent outcomes. Several centers report long-term survival with Fontan pathway as well. We have selectively applied both approaches depending on individual patient morphology, preferred but utilizing when high technical complexity or operative risk is anticipated. Methods Hospital records over an 18-year period (1998–2016) were reviewed to identify patients who underwent surgical...
<ns4:p>Surgical repair of tetralogy Fallot (ToF) in childhood is associated with generally good outcomes, and almost all children can be expected to survive until adulthood. However, significant pulmonary regurgitation leading progressive right ventricular dilatation common teenagers or young adults because the nature surgical intervention. In patients whose included placement a ventricle artery conduit, it has been possible place stented valve within conduit treat this. Pulmonary after ToF...
Abstract Objectives: We report our experience of using the Bentley BeGraft Aortic stent in patients with severe or near-atretic aortic coarctation and small femoral arterial access. Background: Use covered is recommended some settings such as associated aneurysm, Turner syndrome, atresia. However, currently available stents need larger sheaths that may limit their use children smaller Newer overcome this limitation. Methods: Single-centre retrospective study Results: Between July October,...
Abstract Transcatheter creation of an interatrial communication using the Occlutech Atrial Flow Regulator Device for pulmonary hypertension or heart failure is well described. We report a case 8-year-old boy with failing Fontan circulation, in whom was used to successfully create fenestration between artery and left atrium, improving his clinical condition.
To describe the course of an infant with persistent pulmonary hypertension newborn (PPHN) secondary to premature closure ductus arteriosus (DA), a very rare phenomenon which can lead adverse clinical outcomes. A term was diagnosed severe PPHN echocardiographic features noted at 6 h after birth included supra-systemic pressures, isolated right ventricle (RV) hypertrophy, poor RV dysfunction and no ductal flow in context structurally normal heart. There maternal use low-dose aspirin pregnancy...
Background: Stent implantation has become the preferred method of treatment for treating vessel stenosis in congenital heart diseases. The availability covered stents may decrease complications and have an important role management patients with complex anatomy. Aim: This study aims to evaluate feasibility safety pre-mounted cobalt–chromium stent-graft-covered ePTFE Aortic BeGraft a broad spectrum vascular lesions. Methods: is multicenter retrospective results analysis 107 implanted between...
BACKGROUND: Covered stent correction (CSC) of a superior sinus venosus atrial septal defect is an alternative to surgery in selected patients, but anatomic variation means that assessment for CSC requires 3-dimensional understanding. Heart VR virtual reality (VR) system rapidly displays and renders multimodality imaging without prior image segmentation. The aim this study was evaluate the performance assess patient suitability CSC. METHODS: In blinded fashion, 2 interventionalists reviewed...
Carcinoid heart disease is an important complication of neuroendocrine tumors that may lead to significant morbidity and mortality. Right-sided valve involvement with consequent dysfunction one the common manifestations. Patients often have multiple, comorbidities advanced metastatic and, as such, not be suitable for surgical replacement due excessive risk. Transcatheter using balloon-expandable valves has been mainstay management these patients, particularly stenotic lesions but there...