A5030892150- Shoulder Injury and Treatment
- Knee injuries and reconstruction techniques
- Cancer-related gene regulation
- Total Knee Arthroplasty Outcomes
- Reconstructive Surgery and Microvascular Techniques
- Reconstructive Facial Surgery Techniques
- Head and Neck Cancer Studies
- Advanced X-ray and CT Imaging
- RNA modifications and cancer
- Bone and Joint Diseases
- Cancer-related molecular mechanisms research
- Meningioma and schwannoma management
- Orthopaedic implants and arthroplasty
- Orthopedic Infections and Treatments
- Autophagy in Disease and Therapy
- Bone Tumor Diagnosis and Treatments
- Hearing Loss and Rehabilitation
- Osteoarthritis Treatment and Mechanisms
- Nutrition and Health in Aging
- Body Composition Measurement Techniques
- Inflammatory Biomarkers in Disease Prognosis
- Foot and Ankle Surgery
- Facial Trauma and Fracture Management
- Sports injuries and prevention
- Cancer-related Molecular Pathways
Medical University of Vienna
2023-2025
Vienna General Hospital
2024
Background: Young patients with tongue squamous cell carcinoma (TSCC) mostly lack typical prognostic markers and face a dire prognosis. The aim of this study was to analyze the relevance lymphocyte-to-monocyte ratio (LMR) in TSCC patients, special emphasis on under 45 years. Methods: This retrospective included all primarily treated for TSCC. LMR investigated terms predicting overallsurvival (OS) disease-free survival (DFS). Results: A total 74 were young cohort (<45 years) comprised 27...
New chemotherapy agents are warranted for head and neck squamous cell carcinoma (HNSCC), particularly incidence-rising HPV-positive tumors. Based on the evidence of Notch pathway involvement in cancer promotion progression, we aimed to gain insights into vitro antineoplastic effects gamma-secretase inhibition -negative HNSCC models.All experiments were conducted two HPV-negative (Cal27 FaDu) one HPV-associated line (SCC154). The influence inhibitor PF03084014 (PF) proliferation, migration,...
The facial artery perforator flap is a valuable alternative for reconstruction of small to medium defects in the central midface and provide pleasing cosmetic results, allowing one-stage procedure. Since Doppler ultrasound not applicable distinguish from source artery, anatomical studies are needed identify areas along course artery.
Flaps have become an integral part of plastic and reconstructive surgery. The robust blood supply such flaps is a prerequisite to reduce flap failure. Despite the reported versatility occipital flap, comprehensive anatomical studies on its perforators perforasomes are lacking. Hence, we examined originating from artery their associated perforasomes, aiming fill this knowledge gap for surgery techniques.
Background: Osseointegration is essential for the long-term survival of cementless femoral stems and dependent on periprosthetic bone quality correct implantation technique. The aim this study was to evaluate 3-dimensional fixation patterns of, microarchitecture around, hip stems. Methods: Four specimens with varying degrees characteristics from body donors who had received Alloclassic Zweymüller during their lifetime (mean time in situ at death: 12.73 years) were evaluated use radiographs,...
Introduction Even with recent research advances, effective delivery of a compound to its target cells inside the inner ear remains challenging endeavor due anatomical and physiological barriers. Direct intracochlear drug administration an catheter (IEC) aims overcome this obstacle strives provide safe efficient way for pharmacotherapy. The goal study was histologically audiologically evaluate traumatic properties novel IEC in large animal model. Methods Seven ears piglets that had undergone...
Abstract Background Sinonasal malignancies with orbital invasion have dismal prognosis even when treated exenteration (OE). Sugawara et al. developed a surgical strategy called “extended‐OE (EOE),” showing encouraging outcomes. We hypothesized that similar resection is achievable under endoscopic guidance through the exenterated orbit (endoscopic‐EOE). Methods The study was conducted in three institutions: University of Vienna; Mayo Clinic; Insubria; 48 dissections were performed. A...
Abstract Purpose The purpose of this study was to compare the biomechanical properties a latest generation all‐suture anchor repair device (ASARD) for meniscal with that PEEK‐cage (PCARD) in an experimental setting using cadaveric menisci. Methods Twenty‐six menisci were obtained from knees fresh body donors. Artificially created lesions treated randomly, single stitch either ASARD or PCARD. Cyclic testing, utilising universal material testing machine and following established protocol,...
Cancer-associated cachexia in head and neck squamous cell carcinoma (HNSCC) is challenging to diagnose due its complex pathophysiology. This study aimed identify metabolic biomarkers linked survival HNSCC patients using [
During knee arthroscopy, easy orientation is important, and possible landmarks include the lateral intercondylar ridge (LIR) bifurcate (LBR). The objective was to show feasibility of LIR LBR as femoral attachment anterior cruciate ligament (ACL) among subjects with different levels training. Thirty-six formalin-phenol-fixed lower extremities were acquired for this prospective macroscopic anatomical study. All soft tissue apart from ligaments removed. two bundles ACL their origins identified,...
The peroneus tertius muscle (PT) is one of the extensor muscles lower leg, often described as a variable separation from digitorum longus (EDL). According to literature it has six different types insertion, them (Olewnik Type IV) having two tendons inserting fifth metatarsal bone (FMTB). Morphometric data about this type insertion sparse, especially relation between tendons, albeit PT suspected contribute stress fractures FMTB. Therefore, we examined give detailed information on points and...