A5077512125- Spectroscopy Techniques in Biomedical and Chemical Research
- Muscle Physiology and Disorders
- Bee Products Chemical Analysis
- Myofascial pain diagnosis and treatment
- Infrared Thermography in Medicine
- Surgical Simulation and Training
- Planarian Biology and Electrostimulation
- Non-Invasive Vital Sign Monitoring
- Pain Management and Opioid Use
- Anesthesia and Pain Management
- Shoulder Injury and Treatment
- Eating Disorders and Behaviors
- Heart Rate Variability and Autonomic Control
- Facial Nerve Paralysis Treatment and Research
- Osteomyelitis and Bone Disorders Research
- Hip and Femur Fractures
- Acute Myeloid Leukemia Research
- Exercise and Physiological Responses
- Pelvic and Acetabular Injuries
- Muscle activation and electromyography studies
- Pain Mechanisms and Treatments
- Transcranial Magnetic Stimulation Studies
- Muscle metabolism and nutrition
- Hemoglobinopathies and Related Disorders
- Chronic Myeloid Leukemia Treatments
University of Ljubljana
2022-2025
University of Nigeria
2016-2020
Muscle spindles are skeletal muscle sensory receptors composed of intrafusal fibres, partially encapsulated by connective tissue capsule. This capsule encloses the central A and B regions while leaving distal C region extracapsular. Several past studies in rat have shown that typically contain a single bag1 fibre, bag2 two smaller chain fibres. Intrafusal fibres co-express multiple myosin heavy (MyHC) isoforms: -slow or -1, -slow-tonic, -α, -2a, -2b, -embryonic, -neonatal. While MyHC-2x was...
Age, obesity, and diabetes mellitus are pathophysiologically interconnected factors that significantly contribute to the global burden of non-communicable diseases. These metabolic conditions associated with impaired insulin function, which disrupts metabolism carbohydrates, lipids, proteins can lead structural functional changes in skeletal muscle. Therefore, alterations macromolecular composition muscle may provide an indication underlying mechanisms insulin-related disorders. The aim this...
Introduction The global burden of diabetes mellitus is escalating, and more efficient investigative strategies are needed for a deeper understanding underlying pathophysiological mechanisms. crucial role skeletal muscle in carbohydrate lipid metabolism makes it one the most susceptible tissues to diabetes-related metabolic disorders. In tissue studies, conventional histochemical methods have several technical limitations been shown inadequately characterise biomolecular phenotype provide...
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It is not well-understood how type 1 diabetes (T1DM) affects skeletal muscle histological phenotype, particularly capillarisation. This study aimed to analyze myosin heavy chain (MyHC) fibre changes and 3D capillary network characteristics in experimental T1DM mice. Female C57BL/6J-OlaHsd mice were categorized into streptozotocin (STZ)-induced diabetic (n = 12) age-matched non-diabetic controls =12). The phenotype of the soleus, gluteus maximus, gastrocnemius muscles characterized based on...
Little is known regarding the pharmacological properties of extended-release local anesthetics in setting diabetic peripheral neuropathy. We investigated and compared duration sciatic nerve block following administration clinically relevant concentrations liposomal bupivacaine (LB) hydrochloride (BH) mice with In this prospective, randomized, double-blind study, twenty-four female C57BL/6J-OlaHsd were assigned to a streptozotocin-induced type 1 diabetes group control without diabetes. The...
Sickle cell anemia (SCA) is one of the most important genetic disorders known to mankind. Even with impressive advances in medical science, effective treatment and cure remain challenging. Currently available treatments including hydroxyurea, which only FDA approved drug for SCA, hemopoietic stem transplantation all have significant limitations, so search new therapeutic options continues. Metformin, traditional antidiabetic has recently gained novel attention from accumulating molecular...
Despite the significance of neck muscles in musculoskeletal disorders, their microscopic anatomy remains poorly characterized. This study examined splenius capitis muscle, focusing on its fiber-type composition, fiber size, and capillary network characteristics. For comparison validation, vastus lateralis muscle was also analyzed. Muscle samples from 13 young male subjects (mean age ± SD: 35.7 8.6 years) were collected within 24-h post-mortem during autopsy. Myosin heavy chain (MyHC) isoform...