- Parathyroid Disorders and Treatments
- Bone health and treatments
- Thyroid Cancer Diagnosis and Treatment
- Nuclear Structure and Function
- Thyroid Disorders and Treatments
- Growth Hormone and Insulin-like Growth Factors
- Hormonal and reproductive studies
- Diabetes and associated disorders
- Cerebral Venous Sinus Thrombosis
- Medical Imaging and Pathology Studies
- Pituitary Gland Disorders and Treatments
- Glaucoma and retinal disorders
- Inflammasome and immune disorders
- Pancreatic and Hepatic Oncology Research
- Adrenal Hormones and Disorders
- Diet and metabolism studies
- IL-33, ST2, and ILC Pathways
- Neuroendocrine Tumor Research Advances
- Renal Diseases and Glomerulopathies
- Blood disorders and treatments
- Blood properties and coagulation
- Systemic Lupus Erythematosus Research
- Retinal Diseases and Treatments
- Bone health and osteoporosis research
- Bone Metabolism and Diseases
Atatürk University
2015-2024
Erzurum Technical University
2014-2015
Context: Congenital generalized lipodystrophy (CGL) is a rare autosomal recessive disorder characterized by near-total lack of body fat. Objective: We aimed to study natural history and disease burden various subtypes CGL. Design: attempted ascertain nearly all patients with CGL in Turkey. Setting: This was nationwide study. Patients or Other Participants: Participants included 33 (22 families) 30 healthy controls. Main Outcome Measure(s): wanted genotypes sequencing the known genes....
To evaluate retinal nerve fiber layer (RNFL) thickness in early-stage diabetic retinopathy (DR) patients with and without vitamin D deficiency (VDD).This study compared 50 DR VDD (group 1) 2). All were examined by the same ophthalmologist. Mean RNFL was determined optical coherence tomography (OCT) performed two independent ophthalmologists for all subjects. Vitamin levels measured using a radioimmunoassay. defined, accordance general standards, as 25-hydroxyvitamin (25(OH)D) level lower...
Primary hyperparathyroidism is a fairly frequent pathologic diagnosis characterized by hypersecretion of parathyroid hormone, which results from adenomas in 80% to 85% all cases. At clinical onset, the most common symptoms are hypercalcemia-related and some them pain due kidney stones, polyuria, gastrointestinal, neurologic disorders, whereas rarer brown tumors expansive lesions often found fibrocystic osteitis. Brown represent terminal stage remodeling processes caused an increased...
This study was carried out to assess the protective bone-sparing effect of carnitine with anti-inflammatory properties on chronic inflammation-induced bone loss in ovariectomised (OVX) rats. A total 64 rats were divided into eight groups. Sixteen sham-operated (SH) while others (OVX). (1) SH, (2) sham + inflammation (SHinf), (3) OVX, (4) ovariectomy (OVXinf), (5) OVX CAR1, (6) CAR2, (7) OVXinf (8) CAR2. After surgery, all groups (3, 4, 5, 6, 7, and 8) allowed recover for two months. Sixty...
Summary Objectives Lipodystrophy syndromes are a group of heterogeneous disorders characterized by adipose tissue loss. Proteinuria is remarkable finding in previous reports. Study design In this multicentre study, prospective follow‐up data were collected from 103 subjects with non‐ HIV ‐associated lipodystrophy registered the Turkish Group database to study renal complications treatment naïve patients lipodystrophy. Methods Main outcome measures included ascertainment chronic kidney...
Objective: Self-monitoring of blood glucose (SMBG) is a fairly efficient method preventing hypoglycaemia in diabetic patients. Blood meters (BGMs) are influenced by factors such as altitude, temperature, oxygen concentration, low atmospheric pressure or humidity. In this study we aimed at evaluating the performance dehydrogenase (GDH) oxidase (GOX) based glucometers moderately high altitude.Method: A total 286 female male patients, most whom had type 2 diabetes, were included study. The...
Exophthalmometry is a simple examination procedure used for the early diagnosis of many orbital pathologies. The exophthalmometric measures tend to vary with age, sex, and race. Therefore, lot investigators conducted researches determine minimum, maximum, normal values in their populations.We planned this study gather data about our population.In study, 240 male female subjects age ranging from 3 80 years were included. results both eyes evaluated subjects. protrusions measured...
Purpose: Sexual health is not only the absence of sexual dysfunction or disability, but also presence physical, emotional, mental, and social well-being related to sexuality.The current study aims determine whether all adult patients who have applied for their regular check-ups due diabetes mellitus had ever voluntarily expressed problems a specialist they were asked about dysfunction.It how physicians attach importance issue.Patients Methods: All aged 18-65 years with type 1 2 mellitus, our...
Primary and metastatic malignancies of the sternum are uncommon. Secondary lesions to occur more commonly in patients with lung breast cancer, only a few cases sternal metastasis arising from follicular thyroid carcinoma have been reported literature. Rarely, metastases present guise primary tumours may be treated surgically that diagnosis mind. We describe case mass by radical surgery, which ultimately proved solitary thyroid, appearing 13 years after total thyroidectomy radioactive iodine...
Purpose: Endothelial cell-specific molecule-1, endocan, is a proteoglycan that expressed by the vascular endothelium. Endocan can be biomarker of endothelial dysfunction caused cell-dependent disorders. an early step atherosclerosis and developed in hypothyroid patients, which indicates association between hypothyroidism atherosclerosis. Therefore, we aimed to investigate whether circulating endocan levels are associated with overt patients. Materials methods: Forty patients diagnosed last 5...
The pathogenesis of familial Mediterranean fever (FMF) is unknown, and since no specific laboratory test yet available, the diagnosis FMF remains clinical. purpose this study was to review clinical characteristics patients with FMF.A total 96 were evaluated either retrospectively (for those diagnosed before 1997) or prospectively after 1997).The records 54 male 42 female studied. All Turks. Family history positive in 72 (75%). Involved site peritoneum 73 (76%), joints 65 (68%), pleura 16...
Pituitary insufficiency secondary to internal carotid artery (ICA) aneurysm is a very rare condition. Its prevalence reported as 0.17% (Heshmati et al., 2001). We present case of pituitary and hyperprolactinemia suprasellar giant intracranial aneurysm. A 71-year-old man was admitted our clinic with symptoms hypopituitarism, hyperprolactinemia, visual field defect. His MRI cerebral angiography revealed saccular filling cistern arising from the ophthalmic segment right ICA. Endovascular...
The purpose of this study was to determine possible cut-off levels basal DHEA-S percentile rank in the differential diagnosis patients with Cushing's syndrome (CS) ACTH gray zone and normal levels. In retrospective including 623 pathologically confirmed CS, calculated 389 within reference interval. were classified as group 1 (n=265 disease; CD), 2 (n=104 adrenal CS) 3 (n=20 ectopic syndrome).ROC-curve analyses used calculate optimal level interval effectiveness identification accurate...
Secondary amyloidosis (AA amyloidosis) is a well known cause of nephrotic syndrome and renal failure. Several studies in patients with have suggested beneficial effect angiotensin-converting enzyme inhibitors (ACEI). Angiotensin II (ATII) receptor antagonists on the long term not known. In this study, we intended to study losartan, as an ATII antagonist, proteinuria functions normotensive secondary amyloidosis. total 44 biopsy proven AA associated were included. The first group (n=22) was...
Diabetic retinopathy is a leading cause of blindness. not only seen in diabetic patients with the clinical diagnosis but also prediabetic patients. The aim this study to evaluate RNFL thickness patients.In study, 50 and healthy individuals were included. measurements performed SD-OCT prediabetes controls.The mean for group was 94.7 ± 6.3 μm, inferior quadrant (120 11.6), superior (112.3 14.13), nasal (71 12.9), temporal (65.3 9.2 μm). control 98.9 7.5 (128 14.7), (116.3 15.12), (77 15.8),...