To project the number of people with diagnosed diabetes in U.S. through 2050, accounting for changing demography and prevalence rates.We combined age-, sex-, race-specific rates-predicted from 1980-1998 trends data National Health Interview Survey-with Bureau Census population demographic projections. Sensitivity analyses were performed by varying both rate projections.The Americans is projected to increase 165%, 11 million 2000 (prevalence 4.0%) 29 2050 7.2%). The largest percent will be...

Background: The Diabetes Prevention Program (DPP) demonstrated that interventions can delay or prevent the development of type 2 diabetes. Objective: To estimate lifetime cost–utility DPP interventions. Design: Markov simulation model to progression disease, costs, and quality life. Data Sources: published reports. Target Population: Members cohort 25 years age older with impaired glucose tolerance. Time Horizon: Lifetime. Perspectives: Health system societal. Interventions: Intensive...

OBJECTIVE—The purpose of this study was to examine whether glycemic control has improved in recent years among individuals with diagnosed diabetes. RESEARCH DESIGN AND METHODS—We examined trends A1C levels for adults diabetes using three consecutive waves the National Health and Nutrition Examination Survey (NHANES): 1999–2000, 2001–2002, 2003–2004. We estimated mean proportion <7.0, <8.0, <9.0%. used multivariate regression test differed by NHANES wave after controlling...

Estimates of the medical costs associated with different stages CKD are needed to assess economic benefits interventions that slow progression kidney disease. We combined laboratory data from National Health and Nutrition Examination Survey expenditure Medicare claims estimate program's annual were attributable stage 1-4. The for persons who have 1 disease not significantly zero. Per person expenses $1700 2, $3500 3, $12,700 4, adjusted 2010 dollars. Our findings suggest substantial among...

Background: No randomized, controlled trial of screening for diabetes has been conducted. In the absence direct evidence, cost-effectiveness models may provide guidance about preferred strategies. Objective: To estimate incremental 2 strategies: targeted to people with hypertension and universal screening. Design: Markov model. Data Sources: United Kingdom Prospective Diabetes Study, Hypertension Optimal Treatment trial, recent cost data. Target Population: General primary care population in...

Diabet. Med. 29, 453–463 (2012) Abstract Aims To estimate remaining life expectancy (RLE), quality‐adjusted (QALE), causes of death and lifetime cumulative incidence microvascular/macrovascular complications diabetes for youths diagnosed with Type 2 diabetes. Methods A Markov‐like computer model simulated the course a hypothetical cohort adolescents/young adults in USA, aged 15–24 years, newly following either conventional or intensive treatment based on UK Prospective Diabetes Study....

To analyze the cost-effectiveness of bariatric surgery in severely obese (BMI >or=35 kg/m(2)) adults who have diabetes, using a validated diabetes model.We expanded Centers for Disease Control and Prevention-RTI Diabetes Cost-Effectiveness Model to incorporate surgery. In this simulation model, may lead remission reductions other risk factors, which then fewer complications increased quality life (QoL). Surgery is also associated with perioperative mortality subsequent complications,...

This study presents nationally representative estimates of individual and aggregate years‐of‐life‐lost (YLLs) associated with overweight three categories obesity separately by age, race, smoking status, gender strata. Using proportional hazards analysis data from the National Health Interview Survey (NHIS) Linked Mortality Files, we estimated life expectancies for each BMI strata quantified YLLs comparing differences between normal reference group. Our results provide further evidence that...

The authors examine the effects of public subsidies on living arrangements disabled elderly who choose among independently, in an intergenerational household, and entering a nursing home. After quantifying state policies each arrangement, they estimate model using multinominal probit data from National Long-Term Care Survey. Direct for home care which limit beds or reimbursement significantly affect choice arrangement. State subsidize community have little effect entry, although increase...

To estimate the cost-effectiveness of screening overweight and obese individuals for pre-diabetes then modifying their lifestyle based on Diabetes Prevention Program (DPP).A Markov simulation model was used to disease progression, costs, quality life. Cost-effectiveness evaluated from a health care system perspective. We considered two screening/treatment strategies pre-diabetes. Strategy 1 included subjects giving them intervention in DPP if they were diagnosed with both impaired glucose...

The increasing health and economic burden of diabetes has made preventing the disease a public priority. But investing in such chronic prevention programs requires long-term horizon because many years may be required for downstream savings to fully offset up-front intervention cost. Using simulation model, we projected costs benefits nationwide community-based lifestyle program type 2 diabetes. Accounting all US care system, our results indicate that would break even fourteen years. Within...

Abstract Background and aims Effective strategies are needed to address dramatic increases in hepatitis C virus (HCV) infection among people who inject drugs (PWID) rural settings of the United States. We determined required scale‐up HCV treatment with or without prevention interventions achieve a 90% reduction chronic prevalence incidence by 2025 2030 US setting. Design An ordinary differential equation model transmission calibrated epidemiological data obtained primarily from an HIV...

This study develops and tests a model of supply children's time to disabled elderly parents, using data from the National Long‐Term Care Survey. The model, which assumes strategic behavior among relatives, offers predictions about effects changes in price paid personal care, parent's wealth, kid's wage rates, public in‐kind subsidies relative bargaining power on care provided by children. Although several statistically significant relationships are obtained, evidence does not generally...

Purpose The purpose of this study is to estimate the cost-effectiveness diabetes self-management programs in real-world community primary care settings. Estimates incorporated lifetime reductions disease progression, costs adverse events, and increases quality life. Methods Clinical results were based on Diabetes Initiative Robert Wood Johnson Foundation, implemented settings disadvantaged areas with notable health disparities. Program used as inputs a Markov simulation model long-term...