A5005234873- Nail Diseases and Treatments
- Cancer and Skin Lesions
- Acne and Rosacea Treatments and Effects
- Dermatology and Skin Diseases
- Dermatologic Treatments and Research
- Cutaneous lymphoproliferative disorders research
- Genetic and rare skin diseases.
- Nonmelanoma Skin Cancer Studies
- Lymphoma Diagnosis and Treatment
- Skin Protection and Aging
- Contact Dermatitis and Allergies
- Cutaneous Melanoma Detection and Management
- Fungal Infections and Studies
- Skin and Cellular Biology Research
- Psoriasis: Treatment and Pathogenesis
- Autoimmune Bullous Skin Diseases
- melanin and skin pigmentation
- Genital Health and Disease
- Skin Diseases and Diabetes
- Healthcare and Venom Research
- Hedgehog Signaling Pathway Studies
- Herpesvirus Infections and Treatments
- Sarcoma Diagnosis and Treatment
- Infectious Diseases and Mycology
- Oral Health Pathology and Treatment
Hallym University Sacred Heart Hospital
2015-2024
Hallym University
2013-2024
CHA University
2011-2013
Chungbuk National University Hospital
2013
CHA Bundang Medical Center
2011-2013
Hanyang University
2010
Sacred Heart Hospital
2010
Hallym University Medical Center
2008
Psoriasis exerts significant, negative, impact on patients' quality of life (QOL). Recently, the relationship between QOL and skin lesion improvement has been emphasized in treatment psoriasis patients.The purpose study was to compare other diseases, evaluate generic QOL, specific stress, depression anxiety before after patients.A total 138 patients with were recruited this 83 complete questionnaire at week 16. Questionnaires comprised WHO scale, dermatology questionnaires (Skindex-29),...
Summary Background Platelet‐rich plasma (PRP) is a blood fraction that contains high concentrations of several growth factors. PRP has been recently used in skin wound healing and rejuvenation. However, the precise molecular mechanisms underlying PRP‐induced are unknown. Aims This study aimed to evaluate effects on extracellular matrix remodeling, which requires activation dermal fibroblasts. Methods Cell proliferation migration assay, enzyme‐linked immunosorbent analysis, Western blotting...
Hidradenitis suppurativa (HS) is a chronic, relapsing, inflammatory skin disorder. Although several epidemiological studies have been conducted in Western countries, such data regarding Asian populations are scarce. In this study, we sought to investigate the demographic and clinical features of HS Korea. A total 438 patients, diagnosed with from May 2007 April 2017, were enrolled electronic medical record each patient was reviewed. Male patients predominant male : female ratio 2.5:1. Mean...
Polydeoxyribonucleotide (PDRN) is a mixture of deoxyribonucleotides. It serves as an anti‑inflammatory and tissue‑regenerating agent. The mitogen‑activated protein kinase pathway modulates cell growth collagen accumulation. also regulates inflammation by suppressing the expression proinflammatory cytokines. In present study, it was attempted to elucidate molecular mechanism PDRN in skin healing confirming effects treatment on keratinocytes fibroblasts, assessing levels inflammatory cytokines...
Abstract Background Acne is a common skin disorder that affects both adolescents and adults. However, few epidemiological studies on this condition have been conducted in Asia. Objectives The purpose of study was to analyze the incidence acne identify its demographic clinical features aggravating factors. In addition, we examined relationships between these Methods Epidemiological data were obtained, using self‐administered questionnaire, from patients who visited 17 general hospitals...
The anterior neck is the site of open thyroidectomy and where postoperative scarring can cause distress to patients. Both fractional pulsed-dye lasers are effective safe methods for preventing improving surgical scars. This study evaluated improvement in scar appearance with laser intervention during wound healing process. We effect nonablative on fresh Patients were treated 3 times at 4-week interval a follow-up visit 6(th) month. Scars divided into 2 halves each optional treatment. At...
Overexpression of cyclooxygenase-2 (COX-2) has been demonstrated in various cancers, including experimentally promoted tumors, gastrointestinal breast tumors and skin tumors. The mechanism that controls COX-2 expression is not yet clear. Currently, it reported frequently associated with mutated p53 genes. goal this study was to evaluate the patterns several their correlation. An immunohistochemical method used investigate proteins on formalin-fixed, paraffin-embedded tissue specimens...
Psychological stressors may cause affective disorders, such as depression and anxiety, by altering expressions of corticotropin releasing factor (CRF), serotonin (5-HT), tyrosine hydroxylase (TH) in the brain. This study investigated effects essential oil from Asarum heterotropoides (EOAH) on depression-like behaviors brain CRF, 5-HT, TH mice challenged with stress.Male ICR received fragrance inhalation EOAH (0.25, 0.5, 1.0, 2.0 g) for 3 h special cage capped a filter paper before start...
Background: Lichen amyloidosis (LA) is the most common form of localized cutaneous amyloidosis, often accompanied by severe pruritus. Treatment options are limited, and alitretinoin, a systemic retinoid, has shown promise in managing refractory cases. Objective: This study aimed to evaluate efficacy alitretinoin treating LA its effects on keratinocytes. Methods: We conducted retrospective analysis 13 patients diagnosed with treated alitretinoin. In addition, an vitro assessed impact...
Rosacea is a chronic inflammatory disease characterized by centrofacial erythema. Excess cathelicidin suggested to be important the pathophysiology of disease. Recently, presence vitamin D response element was revealed in gene promoter. The aim this study determine whether and are associated with rosacea, both serologically histopathologically. Subjects rosacea without skin disorders were enrolled patient control groups, respectively. Serum 25-hydroxy-vitamin levels measured. Tissue...
Botulinum toxin type A (BTxA) injection is effective for surgical scar prevention. Although some studies have aimed to confirm the efficacy of BTxA at different time points, none has been conducted determine most appropriate timing management. The authors predicted that times during wound healing process would cause differing quality improvement and clarify unknown molecular mechanisms.The study included adults who underwent thyroidectomy. All patients received paralesional injections on day...
Little is known about the treatment-seeking behaviors of acne patients, especially Asian patients. This study was performed to obtain detailed information in Korean Patients who visited dermatology departments at 17 university hospitals completed a self-administered questionnaire. Most patients obtained from doctors or Internet. The most important criteria for selecting treatment method choosing particular clinic were effectiveness and accessibility. used traditional medicine, beauty...
Abstract Rosacea is a common chronic inflammatory skin condition. Although several epidemiological and etiologic studies with large sample sizes have been conducted on Caucasians, such data regarding Asian populations are lacking. A total of 580 patients diagnosed rosacea were enrolled from October 2014 to February 2015 at 14 general hospitals. Questionnaires, including the standard classification grading system, used for evaluation. The average age was 47.9 years. While 83.8% revealed...
Longitudinal melanonychia is not frequently observed in children, and few studies exist on longitudinal paediatric patients, especially Asian populations. We aimed to evaluate the clinical histological findings of Korean patients. A retrospective review patients (≤18 years old) with who underwent nail biopsy between January 2010 October 2015 was performed. Of a total 21 melanonychia, there were 10 cases functional eight lentigo, three nevus, as determined by microscopic examination. Mild...
Lichen nitidus (LN) is an uncommon, usually asymptomatic cutaneous eruption characterized by the presence of multiple, small, flesh-colored papules.The epidemiologic and pathophysiologic characteristics LN have not yet been defined.Furthermore, has rarely described in association with other diseases.We herein report 3 cases associated various diseases, including lichen striatus, oral planus, psoriasis vulgaris.(Ann Dermatol 26(4) 505∼509, 2014)
Background: Rosacea is characterized by erythema on face, especially and linear telangiectasia the nose. Currently, various vascular lasers are used for treatment, among them, long-pulsed Nd:YAG(LPNY) pulsed dye laser (PDL). Objectives: This study compared efficacy of LPNY PDL in treating rosacea-associated nasal telangiectasia. Methods: Patients with rosacea who showed nose were included. Each patient was treated left side bridge, right side, three times 4-week intervals. At end two...
Introduction: Severe onychomycosis in the elderly is a common condition and generally difficult to treat. Long-pulsed Nd:YAG (LPNY) laser has been found be useful treatment of onychomycosis. We sought evaluate effectiveness 1,064-nm LPNY severe Materials methods: Forty nails 13 patients with were divided into two groups. Each group received eight sessions at one-week intervals laser. Parameters for A 0.3 ms pulse duration, 5 mm spot size, 16 J/cm2 fluence, 10 Hz frequency, those B 0.6 ms, 2...
Benign lichenoid keratosis is a cutaneous entity that consists of nonpruritic papule or slightly indurated plaque histologically characterized by band-like inflammatory infiltrate with interface involvement. The purpose this study was to investigate the clinical and histopathologic features benign localized on face. Fourteen patients diagnosed clinically histopathologically in our clinic during 10-year period from 2002 2012 were studied. Thirteen female 1 male included. mean age at diagnosis...
Recently, the number of domestic pets has increased. As a consequence, sensitization to animal allergens, such as cat or dog become problem.We studied annual trends cats dogs, and characteristics patients.We retrospectively analyzed medical records 7,469 patients who visited dermatology clinic underwent an allergic profile test, from January 2011 December 2015. Specific immunoglobulin E (IgE) levels antibody greater than 3.50 IU/ml were regarded positive results.In all, 274 showed...