A5076013134- Fluid Dynamics and Mixing
- Minerals Flotation and Separation Techniques
- Viral Infectious Diseases and Gene Expression in Insects
- Catalysis and Hydrodesulfurization Studies
- Neuroscience and Neuropharmacology Research
- Metal Extraction and Bioleaching
- Innovative Microfluidic and Catalytic Techniques Innovation
- Mine drainage and remediation techniques
- Biofuel production and bioconversion
- Polysaccharides Composition and Applications
- Advanced Control Systems Optimization
- Adenosine and Purinergic Signaling
- Neuropeptides and Animal Physiology
- Microbial Metabolic Engineering and Bioproduction
- Ion channel regulation and function
- Nitric Oxide and Endothelin Effects
- Industrial Gas Emission Control
- Neurological Complications and Syndromes
- Nicotinic Acetylcholine Receptors Study
- Polysaccharides and Plant Cell Walls
- Algal biology and biofuel production
- Lipid Membrane Structure and Behavior
- Wastewater Treatment and Nitrogen Removal
- Enzyme Catalysis and Immobilization
- Extraction and Separation Processes
Universidad Complutense de Madrid
2010-2020
Universidad de León
1995-2006
Universidade de Vigo
2006
University of Coimbra
1998
MRC Centre for Reproductive Health
1997
University of Göttingen
1992
Abstract Oxygen mass transfer in sparged stirred tank bioreactors has been studied. The rate of oxygen into a culture bioreactor is affected by operational conditions and geometrical parameters as well the physicochemical properties medium (nutrients, substances excreted micro‐organism, surface active agents that are often added to medium) presence micro‐organism. Thus, coefficient values fermentation broths differ substantially from estimated for simple aqueous solutions. influence liquid...
1 Diadenosine tetraphosphate (Ap4A) evoked a concentration-dependent increase in cytosolic [Ca2+] resting chromaffin cells. The EC50 value for this action was 28.2 ± 6.6 μm. This effect also produced by diadenosine pentaphosphate (Ap5A) with an of 50 7 2 In contrast effect, pretreatment Ap4A or Ap5A induced 30% reduction Ca2+ entry following 10 μm dimethylphenylpiperazinium. 3 elevation AP4A persistent ≅ 100 nm external and sensitive to depletion internal stores bradykinin prepulse whole...
The action of several diadenosine polyphosphates (AP 3 A, AP 4 A and 5 A) on basal, nicotine‐and high K + ‐evoked, catecholamine (CA) release has been investigated. Each the three weakly but significantly increased basal CA secretion. This enhancement represented about 10% response evoked by 2 μ m nicotine. secretory to had an absolute requirement for extracellular Ca 2+ . In contrast, these compounds inhibitory nicotine‐evoked release. was concentration‐dependent, EC 50 values being 3.2 ±...
Oxygen-uptake and oxygen mass-transfer rates in cultures of Pseudomonas putida [a genetically modified organism (GMO) able to desulfurize dibenzothiophene its derivatives] have been determined a stirred tank bioreactor under different transport conditions. The oxygen-uptake rate has measured by applying dynamic method using step pure oxygen, because the very low concentration broth. A kinetic model is proposed, obtaining parameter values: specific maintenance yield coefficients. Volumetric...
Abstract BACKGROUND In this work, the scale‐up of biodesulfurization process at rest from shaken flask to stirred tank bioreactor cells has been studied taking into account influence hydrodynamic conditions oxygen transfer rate. RESULTS Different carry out in a have and compared with results obtained flask. The best were stirrer speed 400 rpm an air flow rate 2 vvm. found be rate‐limiting step, there is critical value, determined by value for volumetric mass coefficient ( k L ) around 1.4 ×...
Abstract GABA stimulates the basal catecholamine release from adrenal bovine chromaffin cells in a calciumdependent manner. This represents about 70% of that obtained by similar doses nicotine under experimental conditions. effect is mediated A receptor sites present cells, since it was mimicked muscimol and reversed bicuculline. In addition, GABA, through its receptors, increases evoked submaximal aicotine, but has no on nicotine‐evoked secretion catecholamines when given at maximal doses....