A5101465043- Innovative Microfluidic and Catalytic Techniques Innovation
- Catalysis and Hydrodesulfurization Studies
- Neurotransmitter Receptor Influence on Behavior
- Liver Disease Diagnosis and Treatment
- Acute Myeloid Leukemia Research
- Neuroscience and Neuropharmacology Research
- Hepatitis B Virus Studies
- Hematopoietic Stem Cell Transplantation
- Research on Leishmaniasis Studies
- Hepatitis C virus research
- Parkinson's Disease Mechanisms and Treatments
- Hepatocellular Carcinoma Treatment and Prognosis
- Catalysis for Biomass Conversion
- Mast cells and histamine
- Complement system in diseases
- Chronic Myeloid Leukemia Treatments
- Fluid Dynamics and Mixing
- Allergic Rhinitis and Sensitization
- Sympathectomy and Hyperhidrosis Treatments
- Wastewater Treatment and Nitrogen Removal
- Calcium signaling and nucleotide metabolism
- Birth, Development, and Health
- Extracellular vesicles in disease
- Vector-Borne Animal Diseases
- Food Allergy and Anaphylaxis Research
Hospital Universitario 12 De Octubre
2023
Complejo Hospitalario de Salamanca
2022
Instituto de Salud Carlos III
2009-2018
Centro Nacional de Microbiologia
2018
Universidad Complutense de Madrid
2004-2016
Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas
2011
Instituto de Parasitología y Biomedicina "López - Neyra"
2006-2010
Instituto Cajal
2002-2009
Centro de Investigación Biomédica en Red
2009
The influence of working conditions on the growth batch Pseudomonas putida CECT5279 has been studied, in regard to both rate and desulfurization capability accumulated cells. These operational include pH (buffered nonbuffered media, using different carbon sources (glucose, citrate, glutamic acid)), operating temperatures (26−32 °C), dissolved oxygen concentrations, due aeration (different air flows, enriched air, etc.). CECT5979, which is a genetically modified microorganism (GMO), ability...
The production of a biocatalyst genetically modified microorganism (GMO) (Pseudomonas putida CECT5279) that can desulfurize dibenzothiophene (DBT) has been studied. biomass growth rate and the development sulfur-removal capability during have measured modeled. Different media different carbon−glucose, carbon−citrate, carbon−glutamic acid sources, as well nitrogen−ammonium and/or nitrogen−glutamic used, in addition to glutamic concentrations (5, 10, 20, 40 g/L), study their influence on...
In the present study plasma samples from 15 systemic lupus erythematosus (SLE) patients and 16 healthy controls of initially unknown haptoglobin (Hp) phenotype were separated by 2-DE, tryptic digests excised Hpα polypeptide chain spots analyzed MALDI-TOF-MS. Selected peptides sequenced nano-(n)ESI-IT MS/MS. The six major Hp phenotypes present, although with distinct frequencies in SLE patients. Thus, there an increased proportion 2–2, or 2–1S phenotypes. distribution resulted allele 0 625...
Oxygen-uptake and oxygen mass-transfer rates in cultures of Pseudomonas putida [a genetically modified organism (GMO) able to desulfurize dibenzothiophene its derivatives] have been determined a stirred tank bioreactor under different transport conditions. The oxygen-uptake rate has measured by applying dynamic method using step pure oxygen, because the very low concentration broth. A kinetic model is proposed, obtaining parameter values: specific maintenance yield coefficients. Volumetric...
To evaluates the effectiveness and safety of first generation, NS3/4A protease inhibitors (PIs) in clinical practice against chronic C virus, especially patients with advanced fibrosis.Prospective study non-experimental analysis a multicentre cohort 38 Spanish hospitals that includes hepatitis genotype 1, treatment-naïve (TN) or treatment-experienced (TE), who underwent triple therapy generation inhibitors, boceprevir (BOC) telaprevir (TVR), combination pegylated interferon ribavirin. The...
Obesity is associated with high prevalence of hepatic steatosis. We speculate that determinant factors susceptibility to steatosis in obesity could differ between children and adolescents.Blood biochemical parameters, systemic oxidative stress markers, proinflammatory cytokines, adipokine levels were determined 157 obese adolescents. The subjects divided into 2 groups: adolescents, identified as such accordance Tanner stage the measured level dehydroepiandrosterone sulphate. Steatosis was...
The influence of operational conditions (pH, temperature and oxygen transfer rate) on the initial reaction rates four reactions involved in 4S biodesulfurization route dibenzothiophenes (DBT) has been studied. bioprocess was carried out using a genetically modified organism, Pseudomonas putida CECT 5279. were calculated from production different compounds pathway, by matrix manipulation. (zero time) showed slight dependence rate. Temperature pH optimal at 30°C 9, respectively, being most...