- Nutrition and Health in Aging
- Cancer survivorship and care
- Palliative Care and End-of-Life Issues
- Clinical Nutrition and Gastroenterology
- Childhood Cancer Survivors' Quality of Life
- Diet and metabolism studies
- Frailty in Older Adults
- Gastric Cancer Management and Outcomes
- Cancer Risks and Factors
- Nutritional Studies and Diet
- Enhanced Recovery After Surgery
- Gastrointestinal motility and disorders
- Lymphatic System and Diseases
- Effects of Radiation Exposure
- Health Systems, Economic Evaluations, Quality of Life
- Endometrial and Cervical Cancer Treatments
- Helicobacter pylori-related gastroenterology studies
- Dietary Effects on Health
- Esophageal and GI Pathology
- Metabolism, Diabetes, and Cancer
- Ovarian cancer diagnosis and treatment
- Dysphagia Assessment and Management
- Gastroesophageal reflux and treatments
- Delphi Technique in Research
- Cardiac, Anesthesia and Surgical Outcomes
Institute of Cancer Research
2019-2025
Royal Marsden NHS Foundation Trust
2016-2025
Royal Marsden Hospital
1990-2024
NIHR Biomedical Research Centre at The Royal Marsden and the ICR
2024
Royal Alexandra Hospital
2024
Institute of Cancer Research
2023
University of the Witwatersrand
2022
Imperial College London
2022
National Health Service
2007-2021
NIHR Clinical Research Network
2021
Abstract BACKGROUND. Obesity is considered a risk factor for the development of breast cancer‐related lymphedema arm and as poor prognostic in response to treatment. The objective this study was examine weight reduction treatment lymphedema. METHODS. Twenty‐one women with were randomized either receive dietary advice or booklet on general healthy eating. They monitored 12 weeks. RESULTS. primary outcome measure volume at results indicated significant swollen end 12‐week period ( P = .003)...
Background A recent randomised trial suggested that an algorithmic approach to investigating and managing gastrointestinal symptoms of pelvic radiation disease (PRD) is beneficial specially trained nurses can manage patients as effectively a gastroenterologist. Aims The aim the development peer review guide was make algorithm used in accessible all levels clinician. Methods Experts who with PRD were asked guide, rating each section for agreement recommended measures suggesting amendments if...
Abstract BACKGROUND. Obesity is considered a risk factor for lymphedema of the arm resulting from breast cancer treatment (BCRL) as well poor prognostic in response to treatment. The aim study was compare effect 2 dietary interventions on excess volume BCRL. METHODS. A total 64 women with BCRL were randomized 1 3 groups 24 weeks: 1) weight reduction through reduced energy intake; 2) low‐fat diet no change intake (isoenergetic); 3) control group habitual intake. RESULTS. primary outcome...
Abstract Background Patients with oesophago‐gastric ( OG ) cancer may be at risk of malnutrition, troublesome gastrointestinal symptoms GI and reduced dietary intake in view the tumour location multimodality curative treatment approach. Longitudinal research is lacking. The present study aimed to assess (i) nutritional status how it evolved over first year; (ii) association between scores symptom scores; (iii) nutrient food group pattern. Methods This was a prospective, observational...
<h3>ABSTRACT</h3> This study evaluates the efficacy of low-fat dietary interventions in management gastrointestinal (GI) symptoms due to bile acid malabsorption. In total, 40 patients with GI and a 7-day <sup>75</sup>selenium homocholic taurine (SeHCAT) scan result <20%, were prospectively recruited then advised regarding intervention. Before after intervention, rated their using 10-point numerical scale, recorded intake diaries. After median scores for all decreased, significant...
<h3>ABSTRACT</h3> Dietary fat ingestion triggers bile secretion into the gastrointestinal tract. Bile acid malabsorption affects >1% of population, causing loose stool and other symptoms. The diagnosis is frequently missed. Treatments are often considered ineffective. We evaluated low-fat diets for managing symptoms in these patients. All patients reporting type 6 or 7 were offered a selenium-75 homocholic taurine (SeHCAT) scan. Prospective data with 7-day scan retention <20% analysed....
Malnutrition is an alarming and ongoing healthcare problem globally. has a negative impact on the individual patient, leading to poorer clinical outcomes increased mortality, but also poses economic burden society. Proper identification diagnostics are prerequisites for initiation of treatment. In 2019, Global Leadership Initiative Malnutrition, consensus-based global framework uniformly diagnose malnutrition across populations, settings, countries was published. Identifying treating...
Abstract Background Prehabilitation has shown promise in improving post-operative outcomes for several solid tumour groups. However, prehabilitation programmes are not widely established. Patients with advanced ovarian cancer experience life changing debulking surgery and could benefit from prehabilitation. This study aims to explore the views, experiences, facilitators barriers surrounding a demographically diverse cohort of patients. would help inform an acceptable patient-centred working...
This paper reports on a study of perspectives rehabilitation needs by 33 people treated for upper gastrointestinal and gynaecological cancers. used focus groups informed grounded theory involved adult participants who had completed radical treatment at UK cancer centre. Patients were in the design. Findings indicate that these patients are likely to have ongoing there was poor awareness possible symptoms services. Novel findings include distinct adults cancers regarding their needs. surgical...
<h3>ABSTRACT</h3> There is no national NHS tariff to fund services for patients experiencing long-term bowel and nutritional problems after cancer treatment. In this paper, we report the clinical characteristics outcomes of referred our service estimated cost a completed episode care. Patient characteristics, symptom severity, investigations, diagnoses, number clinic visits referrals elsewhere were recorded in prospective cohort study. During 2013–14, 325 assessment The majority original...
Many palliative care patients experience nutritional problems as their conditions progress. This includes those with progressive neurological conditions, chronic obstructive pulmonary disease (COPD) well advanced cancer. Nutritional issues not only impact physically but also psychologically and can have an effect on caring for them. It is important that are screened appropriately one identifies what symptoms potentially affecting intake. Decisions should always be patient-centred....
The impact of the COVID-19 pandemic (caused by SARS-CoV-2 virus) on individuals with cancer has been profound. It led to increased anxiety, distress and deconditioning due reduced physical activity. We aim investigate whether SafeFit, a multimodal intervention activity, nutrition psychological support delivered virtually exercise specialists (CES), can improve emotional functionings during pandemic.A phase III non-randomised trial, target recruitment 1050 adults suspected or confirmed...