- Pelvic floor disorders treatments
- Anorectal Disease Treatments and Outcomes
- Meta-analysis and systematic reviews
- Urinary Tract Infections Management
- Health Systems, Economic Evaluations, Quality of Life
- Diagnosis and Treatment of Venous Diseases
- Pelvic and Acetabular Injuries
- Clinical practice guidelines implementation
- Patient Satisfaction in Healthcare
- Dermatologic Treatments and Research
- Venous Thromboembolism Diagnosis and Management
- Dupuytren's Contracture and Treatments
- Glaucoma and retinal disorders
- Urinary Bladder and Prostate Research
- Primary Care and Health Outcomes
- Retinal Imaging and Analysis
- Hernia repair and management
- Neurobiology of Language and Bilingualism
- Cardiac, Anesthesia and Surgical Outcomes
- Retinal and Optic Conditions
- Diverticular Disease and Complications
- Mobile Health and mHealth Applications
- Retinal Diseases and Treatments
- Antibiotic Use and Resistance
- Obesity and Health Practices
Glasgow Caledonian University
2015-2024
University of Aberdeen
2011-2019
Royal Devon and Exeter Hospital
2014
Scottish Health Services
2014
National Health Service Scotland
2005-2009
NHS Fife
2008
Martini Ziekenhuis
1982
BackgroundThe use of transvaginal mesh and biological graft material in prolapse surgery is controversial has led to a number enquiries into their safety efficacy. Existing trials these augmentations are individually too small be conclusive. We aimed compare the outcomes repair involving either synthetic inlays or grafts against standard women.MethodsWe did two pragmatic, parallel-group, multicentre, randomised controlled for our study (PROSPECT [PROlapse Surgery: Pragmatic Evaluation...
Ultrasound-guided foam sclerotherapy and endovenous laser ablation are widely used alternatives to surgery for the treatment of varicose veins, but their comparative effectiveness safety remain uncertain.
Abstract Introduction Severe sepsis is associated with high levels of morbidity and mortality, placing a burden on healthcare resources. We aimed to study outcomes in the five years after severe sepsis. Methods This was cohort using data from prospective audit 26 adult ICUs Scotland. Mortality measured clinical databases quality life Short Form 36 (SF-36) at 3.5 5 Results A total 439 patients were recruited 58% mortality 61% years. 85 67 responded follow-up, respectively. SF-36 physical...
To investigate prolapse symptoms and objectively measured pelvic organ prolapse, 12 years after childbirth, association with delivery mode history.Twelve-year longitudinal study.Maternity units in Aberdeen, Birmingham Dunedin.Women dwelling the community.Data from women were collected an index birth invited for examination. Logistic regression investigated associations between risk factors signs.Prolapse symptom score (POP-SS); (POP-Q).Of 7725 continuing women, 3763 (49%) returned...
In an effort to improve the quality of statistics in clinical urology literature, statisticians at European Urology, The Journal Urology and BJU International came together develop a set guidelines address common errors statistical analysis, reporting, interpretation. Authors should ‘break any if it makes scientific sense do so’, but would need provide clear justification. Adoption will our view not only increase published papers journals knowledge field general.
Background Dentists prescribe approximately 10% of antibiotics dispensed in UK community pharmacies. Despite clear clinical guidance, dentists often inappropriately. This cluster-randomised controlled trial used routinely collected National Health Service (NHS) dental prescribing and treatment claim data to compare the impact individualised audit feedback (A&F) interventions on dentists’ antibiotic rates. Methods Findings All 795 NHS general practices Scotland were included. Practices...
Background Foam sclerotherapy (foam) and endovenous laser ablation (EVLA) have emerged as alternative treatments to surgery for patients with varicose veins, but uncertainty exists regarding their effectiveness in the medium longer term. Objectives To assess clinical cost-effectiveness of foam, EVLA treatment veins. Design A parallel-group randomised controlled trial (RCT) without blinding, economic modelling evaluation. Setting Eleven UK specialist vascular centres. Participants Seven...
Endovenous laser ablation and ultrasound-guided foam sclerotherapy are recommended alternatives to surgery for the treatment of primary varicose veins, but their long-term comparative effectiveness remains uncertain.In a randomized, controlled trial involving 798 participants with veins at 11 centers in United Kingdom, we compared outcomes ablation, sclerotherapy, surgery. Primary 5 years were disease-specific quality life generic life, as well cost-effectiveness based on models expected...
You have accessJournal of UrologyOutcomes/Epidemiology/Socioeconomics1 Mar 2019Guidelines for Reporting Statistics Clinical Research in Urology Melissa Assel, Daniel Sjoberg, Andrew Elders, Xuemei Wang, Dezheng Huo, Albert Botchway, Kristin Delfino, Yunhua Fan, Zhiguo Zhao, Tatsuki Koyama, Brent Hollenbeck, Rui Qin, Whitney Zahnd, Emily C. Zabor, Michael W. Kattan, and J. Vickers AsselMelissa Assel Memorial Sloan Kettering Cancer Center, , SjobergDaniel Sjoberg EldersAndrew Elders Glasgow...
Abstract Objective To assess the effectiveness of pelvic floor muscle training (PFMT) plus electromyographic biofeedback or PFMT alone for stress mixed urinary incontinence in women. Design Parallel group randomised controlled trial. Setting 23 community and secondary care centres providing continence Scotland England. Participants 600 women aged 18 older, newly presenting with between February 2014 July 2016: 300 were to alone. Interventions both groups offered six appointments a therapist...
Summary Background While overall hospital admission rates for peptic ulcer declined in England the 1990 s, they increased among elderly, especially complicated ulcer. However, admissions fell all age groups United States. Aim To examine time trends incidence of admissions, mortality and operations because Scotland from 1982 to 2002, use various drugs relevant aetiology treatment 1992 2002. Results There was a general decrease rates, younger individuals. For individuals aged above 74 years,...
Pelvic organ prolapse is a common urogenital condition affecting 41-50% of women over the age 40. To achieve early diagnosis and appropriate treatment, it important that care sensitive to meets women's needs, throughout their patient journey. This study explored experiences seeking treatment for needs priorities improving person-centred care.Twenty-two receiving through urogynaecology services across three purposefully selected NHS UK sites took part in focus groups four telephone...
To determine the long-term (12-year) effects of a conservative nurse-led intervention for postnatal urinary incontinence.Follow-up randomised controlled trial.Community-based in three centres (in UK and New Zealand).A cohort 747 women with incontinence at 3 months after childbirth, whom 471 (63%) were followed up 12 years.Women randomly allocated to active treatment delivery (pelvic floor muscle training bladder training), or control group receiving standard care.Prevalence (primary outcome)...