A5001976899- Coronary Interventions and Diagnostics
- Cardiac Imaging and Diagnostics
- Cardiovascular Function and Risk Factors
- Cardiac Arrhythmias and Treatments
- Acute Myocardial Infarction Research
- Cardiac pacing and defibrillation studies
- Peripheral Artery Disease Management
- Trace Elements in Health
- Cardiac Valve Diseases and Treatments
- Cardiac electrophysiology and arrhythmias
- Cardiovascular Effects of Exercise
- Pulmonary Hypertension Research and Treatments
- Heart Failure Treatment and Management
- Cardiac Structural Anomalies and Repair
- Optical Coherence Tomography Applications
- Pain Management and Treatment
- Antiplatelet Therapy and Cardiovascular Diseases
- Coronary Artery Anomalies
- Ultrasound in Clinical Applications
- Cardiovascular Issues in Pregnancy
- Heart rate and cardiovascular health
- Cerebrovascular and Carotid Artery Diseases
- Mechanical Circulatory Support Devices
- Pericarditis and Cardiac Tamponade
- Cardiac, Anesthesia and Surgical Outcomes
Nemocnice Podlesí
2017-2025
Charles University
2024-2025
Dansk Selskab for Anæstesiologi og Intensiv Medicin (Denmark)
2023
Krajská Zdravotní
2007-2022
Masaryk University
2020
Hutní Projekt Frýdek-Místek (Czechia)
2017-2020
Holografika (Hungary)
2009
Takeda (United Kingdom)
1999
Farmak (Czechia)
1999
University of Regensburg
1999
To assess the role of intravascular ultrasound (IVUS) during implantation drug-eluting stents (DES) on long-term outcome in patients with complex coronary artery disease and high clinical risk profile special attention to development late stent thrombosis (LST).Two hundred ten were randomly assigned receive DES either (N = 105) or without IVUS guidance. Dual antiplatelet treatment was administered for 6 months all patients. At 18-month follow-up, rates major adverse cardiac events (MACEs)...
Background —The renin-angiotensin system plays an important part in the pathogenesis of congestive heart failure (CHF). This study evaluated effect angiotensin II type 1 receptor antagonist on exercise tolerance and symptoms CHF. Methods Results —In this multicenter, double-blind, parallel-group study, 844 patients with CHF were randomized to 12 weeks’ treatment placebo (n=211) or candesartan cilexetil 4 mg (n=208), 8 (n=212), 16 (n=213) after a 4-week run-in period. Changes time, Dyspnea...
This intervention pilot case series assessed 40-Gy stereotactic radiosurgery (SRS) neuromodulation applied to the bilateral stellate ganglion (SG) as a bailout procedure for patients with refractory angina pectoris (RAP). The local institutional review board approved this feasibility study. In three RAP, after repeated good response, symptoms were temporarily relieved anaesthetic blockade of left SG under ultrasound guidance. Radiosurgical dose 40 Gy in one fraction was used more permanent...
Atrial fibrillation (AF) is common in patients with mitral regurgitation (MR) undergoing transcatheter edge-to-edge repair (TEER) MitraClip, but its impact on procedural hemodynamics and clinical outcomes remains inadequately characterized. This retrospective single-centre study analysed 226 high-risk who underwent MitraClip implantation between 2010 2022. The primary endpoint was time to first heart failure hospitalization. Secondary endpoints included long-term mortality. AF present 46.9%...
Abstract Purpose : The aim of this trial was to assess the feasibility and safety endothelial progenitor cells capture (EPC) stent in treatment acute ST‐elevation myocardial infarction (STEMI) when compared with cobalt‐chromium stents (CoCr). Methods Between July 2006 May 2008, 100 patients single vessel disease undergoing primary PCI for STEMI were randomly assigned receive either EPC ( N = 50) or CoCr 50). High‐pressure implantation carried out both groups. Dual antiplatelet administered...
Abstract Background: The aim of this study was to assess neointimal hyperplasia following sirolimus‐eluting (SES) and paclitaxel‐eluting stents (PES) implantation in a patients with complex coronary disease. Method: Between January December 2004, 70 were enrolled (SES = 37; PES 33. primary objective the efficacy SES on proliferation inhibition lesions by volumetric 3D intravascular ultrasound (IVUS) assessment at six‐month follow‐up. Results: Baseline clinical, demographic or angiographic...
For the treatment of patients with electrical storm (ES), we established a two-step algorithm comprising standard anti-arrhythmic measures and early ultrasound-guided stellate ganglion blockade (SGB). In this single-center study, evaluated short-term efficacy tested hypothesis that SGB might prevent need for intubations.Overall, analyzed data 70 ES events in 59 requiring (mean age 67.7 ± 12.4 years, 80% males, left ventricular ejection fraction 30.0% 9.1%), all implantable...
Kontext: Diuretika jsou doporučena ke kontrole symptomů kongesce a retence tekutin u pacientů se srdečním selháním, ale jejich vliv doposud nebyl zkoumán v randomizovaných klinických studiích. Existují konfliktní data o možném pozitivním negativním účinku závislosti na dávce kličkového diuretika. Cílem naší analýzy je vyhodnotit, zda by relativně malé zvýšení dávky furosemidu mohlo snížit výskyt rehospitalizací pro akutní dekompenzaci a/nebo celkovou mortalitu.Metody výsledky: Celkem jsme...
Abstract Background Refractory angina pectoris (AP) significantly impairs quality of life in patients with chronic coronary syndrome. Several minimally invasive methods (coronary sinus reducer, cell therapy, laser or shockwave revascularization, and spinal cord stimulation) non-invasive (external counterpulzation) have been studied. However, their routine clinical use has not widely implemented. Surgical endoscopic sympathectomy is feasible for permanently relieving angina, but often...
Cíl: S použitím optické koherentní tomografie (OCT) posoudit výskyt a charakter plátu v infarktové tepně detekovat případné nestabilní pláty neinfarktových tepen u nemocných s infarktem myokardu elevacemi úseku ST (STEMI) léčených přímou perkutánní koronární intervencí (dPCI).Metodika: Třicet konsekutivních se STEMI postižením jedné tepny bylo zahrnuto do studie. Vyšetření pomocí OCT provedeno po zavedení tenkého intrakoronárního vodiče balonkovou predilatací nebo bez ní. Konečné vyšetření i...
Použití ultrazvuku k punkcím cév a výpotků se stává stále častější. Ultrazvuk v tomto svému uživateli přináší mnoho výhod po určité učební křivce je lékař schopen kanylovat cévy, které jsou malé či jinak nedosažitelné při použití klasických anatomických bodů orientaci. Randomizované studie potvrdily výhody ultra-zvuku kontextu, čímž tato metoda stala standardem pro mnohé lékaře mnohá pracoviště.
Acute pericarditis is a serious and potentially fatal disease in which diagnostic workup not always straightforward. Hiatal hernia, on the other hand, often asymptomatic can be easily diagnosed if symptomatic. In advanced forms of hiatal oppression intrathoracic organs heart failure occur. uncommon cases, large intestine also translocated into chest cavity, very rarely, it perforated with development mediastinitis and/or pericarditis. We report case 74-year-old female 1.5-month history pain...