Headache syndromes often suggest occipital and neck involvement, although it is still unknown to what extent branches of segment C1-C3 contribute actively primary headache. Pain within the area may be referred trigeminal territory. However, a modulation transmission by affecting cervical input in humans has not been elucidated so far. A convergence at level caudal part nucleus brainstem suggested due anatomical neurophysiological studies animals. We examined R2 components nociceptive blink...

Headache syndromes often involve occipital and neck symptoms, suggesting a functional connectivity between nociceptive trigeminal cervical afferents. Although reports regarding effective nerve blockades in cluster headache exist, the reason for improvement of clinical symptoms is not known. Using blockade blink reflexes, we were able to demonstrate nerves healthy volunteers. The R2 components reflex outcome 15 chronic patients examined before after unilateral greater with 5 ml prilocain (1%)...

The goal of this study was to expand knowledge on the longitudinal relationships between motor skill competence, physical activity, perceived health-related fitness, and weight status its age dependency in children 6 11 years old. Participants were Dutch primary school ( N = 1,268 children, 49.4% boys 50.6% girls) divided over three groups, Group 1 (5.5–7.49 years), 2 (7.5–9.49 3 (9.5+ years). Measurements done at baseline (T1) year later (T2). Structural equation modeling resulted a final...

Current studies suggest dysfunctional emotional processing as a key factor in the aetiology of temporomandibular disorder (TMD). Investigating facial emotion recognition (FER) may offer an elegant and reliable way to study patients with TMD. Twenty TMD same number age-, sex- education-matched controls were measured Facially Expressed Emotion Labelling (FEEL) test, 26-item Toronto Alexithymia Scale (TAS-26), Screening for Somatoform Symptoms (SOMS-2a), German Pain Questionnaire 21-item...

ABSTRACT BACKGROUND This study assessed the effects of “Jump‐in” whole‐school intervention in Amsterdam, Netherlands, on children's weight development by comparing children exposed to and controls from 3 other large Dutch cities. Jump‐in is a comprehensive that aims stimulate healthy nutrition physical activity at primary schools Amsterdam. In addition, relationship between intervention's implementation degree its effectiveness was studied. METHODS Demographic anthropometric data, collected...

Occipital stimulation in a small group of refractory chronic migraine and cluster headache patients has been suggested as novel therapeutic approach with promising results. In an earlier study we have shown that drug-induced block the greater occipital nerve (GON) inhibits nociceptive blink reflex (nBR). Now, sought to examine effects low-frequency (3 Hz) short-time GON on trigeminal system. We recorded nBR responses before after 34 healthy subjects. Selectivity was confirmed by eliciting...

A temporary sensitization of central trigeminal neurones in migraine patients during acute attacks has been described previous studies using the electrically evoked nociceptive blink reflex. The cornea is innervated by small myelinated A-delta and unmyelinated C-fibres only. Stimulation with air puffs activates peripheral nociceptors allows investigation nerve structures. Our objective was to investigate whether corneal reflex examinations puff stimulation detect abnormalities migraineurs...

Background: Acupuncture has been suggested to exert its controversial therapeutic effects by modulation of the peripheral and central nervous system. However, acupuncture are still a matter debate, since few direct neurophysiological measures using proper placebo conditions have reported.

Background: The aim of this study was to investigate emotional processing in temporomandibular disorder (TMD) reflected facial emotion recognition (FER). As deficits FER were suggested previously as general feature somatoform disorders (SFD) [1], we searched for analogies between TMD and SFD trying shed light on the etiology TMD. Methods: Twenty patients with same number age, sex education matched healthy controls recruited be measured Facially Expressed Emotion Labelling (FEEL) Test FER,...

Facial nerve palsy is a common symptom in children with broad panel of differential diagnoses, however alternating facial rarely reported and should always be suspicious systemic disorder. We present the case 1 year old boy, who exhibited recurrent one brief transient episode unilateral weakness. Routine examinations during first two episodes including infectiological work-up MRA brain were normal. During third extremely high blood pressure (MAP 200mmHg) was noted associated fundoscopic...

Objective: Demyelination may cause a uniform reduction of the conduction velocity all fibres peripheral nerve segment, or non-uniformly affect only some while sparing others. In latter case routinely determined (NCV) is normal amplitude, duration, and shape compound muscle action potentials (CMAP) vary with distance between stimulus muscle. This study was done to determine if what extent quantitative analysis CMAP shapes has potential differentiate non-uniform slowing.

Fragestellung: Viele Patienten mit idiopathischen Kopfschmerzerkrankungen wie einer Migräne oder einem Clusterkopfschmerz klagen neben klassischerweise trigeminal bedingten frontoorbitalen Schmerzen oft auch über eine Beteiligung von Hinterkopf und Nacken, die okzipitalen Nerven den Segmenten C2–5 versorgt werden. Diese Beobachtung legt funktionelle Verbindung beider Systeme nahe, durch tierexperimentelle Studien anatomischen elektrophysiologischen Nachweis eines „cross talks“ zwischen...

Introduction: Inspiratory pressure 0.1s after onset of inspiration (PI0.1) is thought to reflect the central nervous system respiratory center output (RCO) in healthy children. The purpose this study was investigate whether also true for children with proximal myopathies (PM).

Aicardi syndrome is characterized by the combination of partial or total agenesis corpus callosum, chorioretinal lacunae and infantile spasms. Genetically, patients exhibit alterations in Xp22.1–22.3 locus, resulting lethality males development females.

M. Fabry ist eine X-chromosomal vererbte Lipidstoffwechselerkrankung, die durch das Fehlen oder verminderte Aktivität des α-Galaktosidase-A-Enzyms gekennzeichnet ist. Der mangelnde Katabolismus führt zu einer systemischen Ablagerung von Glykosphyngolipiden und multiplen Organschäden mit tödlichem klinischen Verlauf in der vierten fünften Lebensdekade. Es wird Fall eines männlichen 33-jährigen Patienten typischen neurologischen Symptome dieser Erkrankung Form Schlaganfällen im jungen...