A5041320761- Obsessive-Compulsive Spectrum Disorders
- Autism Spectrum Disorder Research
- Child and Adolescent Psychosocial and Emotional Development
- Eating Disorders and Behaviors
- Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Attention Deficit Hyperactivity Disorder
- Maternal Mental Health During Pregnancy and Postpartum
- Behavioral and Psychological Studies
- Early Childhood Education and Development
- Suicide and Self-Harm Studies
- Youth Substance Use and School Attendance
- Child Nutrition and Feeding Issues
- Sexuality, Behavior, and Technology
- Perfectionism, Procrastination, Anxiety Studies
- Attachment and Relationship Dynamics
- Functional Brain Connectivity Studies
- Body Image and Dysmorphia Studies
- Family and Disability Support Research
- Botulinum Toxin and Related Neurological Disorders
- Child Therapy and Development
- Infant Development and Preterm Care
- Mental Health Research Topics
- Neurotransmitter Receptor Influence on Behavior
- Child and Adolescent Health
- Genetic Associations and Epidemiology
College of Southern Nevada
2024
University of California, Los Angeles
2015-2024
Neurobehavioral Systems
2015-2024
Marquette University
2017-2023
University of Arizona
2023
University of North Carolina at Chapel Hill
2023
John Wiley & Sons (United States)
2023
American Academy of Child and Adolescent Psychiatry
2003-2022
UCLA Health
2007-2021
The Jane Goodall Institute
2020
To describe the NIMH Diagnostic Interview Schedule for Children (DISC) Version 2.3 and to provide data on its performance characteristics in Methods Epidemiology of Child Adolescent Mental Disorders (MECA) Study.Data were collected DISC-2.3 at four sites 1,285 randomly selected children, aged 9 through 17 years, their parents. Two hundred forty-seven these child-parent pairs reassessed by a clinician interviewer, 1 3 weeks later.Administration time was approximately hour interview acceptable...
Anxiety disorders are common psychiatric conditions affecting children and adolescents. Although cognitive behavioral therapy selective serotonin-reuptake inhibitors have shown efficacy in treating these disorders, little is known about their relative or combined efficacy.
Tourette disorder is a chronic and typically impairing childhood-onset neurologic condition. Antipsychotic medications, the first-line treatments for moderate to severe tics, are often associated with adverse effects. Behavioral interventions, although promising, have not been evaluated in large-scale controlled trials.
Drugs that selectively inhibit serotonin reuptake are effective treatments for adults with mood and anxiety disorders, but limited data available on the safety efficacy of serotonin-reuptake inhibitors in children disorders.
Evaluated the concurrent validity of Anxiety Disorders Interview Schedule for Diagnostic and Statistical Manual Mental (4th ed. [DSM-IV], American Psychiatric Association, 1994): Child Parents Versions (ADIS DSM-IV-C/P; Silverman & Albano, 1996) social phobia, separation anxiety disorder (SAD), generalized (GAD), panic diagnoses. Children referred to an outpatient clinic (N = 186; ages 8 17), their parents completed Multidimensional Scale (MASC; March, 1998) ADIS-C/P interview. There was no...
Although obsessive-compulsive disorder (OCD) is a chronic and oftentimes debilitating disorder, the specific impact of this illness on psychosocial functioning affected youngsters has not been systematically described. A total 151 clinic-referred (mean age 11.8 years, 57% male, 83% Caucasian) with primary Diagnostic Statistical Manual Mental Disorders (fourth edition) OCD caretaker completed checklist designed to assess school, social, family functioning. The two most common OCD-related...
Although motor tics and/or vocal are the defining features of chronic tic disorder (CTD) and Tourette syndrome (TS), older youths adults often report their to be preceded by an unpleasant sensation or "premonitory urge." While premonitory urge phenomena may play important role in behavioral interventions for CTD/TS, standardized assessments urges do not exist. The current study 42 with TS CTD presents initial psychometric data a new, brief self-report scale designed measure tic-related...
The direct estimation of heritability from genome-wide common variant data as implemented in the program Genome-wide Complex Trait Analysis (GCTA) has provided a means to quantify attributable all interrogated variants. We have quantified variance liability disease explained by SNPs for two phenotypically-related neurobehavioral disorders, obsessive-compulsive disorder (OCD) and Tourette Syndrome (TS), using GCTA. Our analysis yielded point estimate 0.58 (se = 0.09, p 5.64e-12) TS, 0.37...
To present the design, methods, and rationale of Child/Adolescent Anxiety Multimodal Study (CAMS), a recently completed federally-funded, multi-site, randomized placebo-controlled trial that examined relative efficacy cognitive-behavior therapy (CBT), sertraline (SRT), their combination (COMB) against pill placebo (PBO) for treatment separation anxiety disorder (SAD), generalized (GAD) social phobia (SoP) in children adolescents. Following brief review acute outcomes CAMS trial, as well...
To report on remission rates in anxious youth who participated the Child/Adolescent Anxiety Multimodal Study (CAMS). The CAMS, a multisite clinical trial, randomized 488 children and adolescents (ages 7-17 years; 79% Caucasian; 50% female) with separation, social, and/or generalized anxiety disorder to 12-week treatment of sertraline (SRT), cognitive behavioral therapy (CBT), their combination (COMB), or management pill placebo (PBO).The primary definition was loss all study-entry diagnoses;...
Context: Tics in Tourette syndrome begin childhood, peak early adolescence, and often decrease by adulthood.However, some adult patients continue to have impairing tics.Medications for tics are effective but can cause adverse effects.Behavior therapy may offer an alternative has not been examined a large-scale controlled trial adults.Objective: To test the efficacy of comprehensive behavioral intervention adults with at least moderate severity.Design: A randomized posttreatment evaluations 3...
Background Experts have proposed removing obsessive–compulsive disorder (OCD) from the anxiety disorders section and grouping it with putatively related conditions in DSM-5. The current study uses co-morbidity familiality data to inform these issues. Method Case family OCD Collaborative Genetics Study (382 OCD-affected probands 974 of their first-degree relatives) were compared control Johns Hopkins Family (73 non-OCD-affected 233 relatives). Results Anxiety (especially agoraphobia...
<h3>Importance</h3> Pediatric anxiety disorders are highly prevalent and impairing considered gateway in that they predict adult psychiatric problems. Although can be effectively treated the short term, data limited on long-term outcomes children adolescents, particularly those with medication. <h3>Objective</h3> To determine whether acute clinical improvement treatment type (ie, cognitive behavioral therapy, medication, or their combination) predicted remission of global functioning at a...
We sought to examine predictors and moderators of treatment outcomes among 488 youths ages 7-17 years (50% female; 74% ≤ 12 years) meeting Diagnostic Statistical Manual Mental Disorders (4th ed., text rev.; American Psychiatric Association, 2000) criteria for diagnoses separation anxiety disorder, social phobia, or generalized disorder who were randomly assigned receive either cognitive behavioral therapy (CBT), sertraline (SRT), their combination (COMB), medication management with pill...