- Bipolar Disorder and Treatment
- Semiconductor materials and devices
- Schizophrenia research and treatment
- Nanowire Synthesis and Applications
- Treatment of Major Depression
- Advancements in Semiconductor Devices and Circuit Design
- Body Composition Measurement Techniques
- Rheumatoid Arthritis Research and Therapies
- Silicon Nanostructures and Photoluminescence
- Electroconvulsive Therapy Studies
- Nuclear Physics and Applications
- Semiconductor materials and interfaces
- Tryptophan and brain disorders
- Solid-state spectroscopy and crystallography
- Crystal Structures and Properties
- Mental Health Treatment and Access
- Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Spondyloarthritis Studies and Treatments
- Obsessive-Compulsive Spectrum Disorders
- Cannabis and Cannabinoid Research
- Global Health Care Issues
- Nonlinear Optical Materials Research
- Functional Brain Connectivity Studies
- Thermoregulation and physiological responses
- Boron and Carbon Nanomaterials Research
Applied Materials (United States)
2025
St. Patrick's Hospital
2006-2024
Vhi Healthcare
2024
NHS England
2024
New Zealand Association of Counsellors
2023
Charing Cross Hospital
2023
Swansea Bay University Health Board
2023
Royal Veterinary College
2022
Trinity College Dublin
2013-2020
University College Cork
2018-2020
OBJECTIVE: Despite clear gender differences in the symptoms and course of bipolar affective disorder, studies investigating age at onset by have yielded inconsistent results. The authors investigated incidence first-episode mania disorder an epidemiological catchment area southeast London over a 35-year period. METHOD: All adult cases psychosis, mania, or hypomania presenting to services Camberwell, (1965–1999), were identified. Computerized diagnoses for these generated using Operational...
Rheumatoid arthritis may be associated with generalised as well periarticular osteoporosis. To assess the extent of bone loss and influence corticosteroid treatment total body calcium was measured by in-vivo neutron activation analysis in 63 patients rheumatoid treated non-steroidal anti-inflammatory drugs alone 31 additional low-dose corticosteroids. The results were compared those 40 normal controls matched for age, sex, menopausal state. There significant reductions mean group (5.3% men;...
Background. Long-term studies of severe depression have described high rates non-recovery, recurrence, chronic incapacity and mortality. A more recent cohort was followed-up to ascertain whether the course had improved given developments in pharmacological psychological treatments last 15 years. Method. Subjects from a 70 mainly recurrent depressives originally recruited shorter follow-up study 1990–1992 were after 8–11 Data included longitudinal information on other psychiatric disorders,...
Background. The high risk of suicide in bipolar disorder is well recognized, but may have been overestimated. There conflicting evidence about deaths from other causes and little known factors for suicide. We aimed to estimate mortality rates a cohort patients identify Method. All who presented the first time with DSM-IV diagnosis I defined area southeast London over 35-year period (1965–1999) were identified. Mortality compared those 1991 England Wales population, indirectly standardized...
Background. Few epidemiological studies have investigated incidence by age or at onset distributions for mania bipolar disorder. The current study aimed to determine these in a defined area south-east London, over 35-year period. Method. All cases of first-episode presenting psychiatric services Camberwell, between 1965 and 1999 were identified. Incidence rates age, using 5-year age-at-onset bands, estimated the structure distribution was finite mixture (admixture analysis). Results. DSM-IV...
Few follow-up studies of depression have evaluated depressive symptomatology over time at both threshold and sub-threshold levels.To evaluate long-term longitudinal symptomatic course after an episode severe depression.A total 61 participants from a previous study cohort underwent detailed interview covering the pharmacological treatment 8-11 years follow-up.Of months, 52% were spent asymptomatic level, 15% minor symptom 20% residual level 13% full level. Also, 30% months in depression, 18%...
Background There has been a relative dearth of epidemiological research into bipolar affective disorder. Furthermore, incidence studies disorder have predominantly retrospective and most only included hospital admission cases. Aims To determine the operationally defined in three areas UK to investigate any differences gender ethnicity. Method All patients who contacted mental health services with first-episode psychosis or non-psychotic mania between September 1997 August 1999 were...
There is evidence that cannabis use might be relevant to the aetiology of schizophrenia. We aimed measure any change in over time those first presenting with schizophrenia South-East London from 1965 1999, and compare this non-psychotic psychiatric disorders.The rate year prior ever presentation was measured seven periods. Logistic regression modelling used determine (a) whether changed time, after controlling for age, sex ethnicity, (b) there an interaction between diagnosis time.Cannabis...
The crystal structure if RbH2PO4 has been determined by neutron diffraction at room temperature and Tc+5K in the tetragonal (paraelectric) phase using single-crystal samples. techniques of constrained refinement statistical testing have used to examine carefully significance some pertinent structural features. also 77K orthorhombic (ferroelectric) powder-diffraction methods. results for both phases are compared with those obtained from similar studies KH2PO4. Whilst it is shown that...
SYNOPSIS A series of elderly patients with dementia Alzheimer type (AD), multi-infarct (MID) and functional (non-organic) psychiatric illness (major depressive disorder) were selected according to DSM-III-R criteria received: a battery cognitive tests, EEG Single Photon Emission Computed Tomography (SPECT) using 99m Tc HMPAO. The SPECT scans examined independently the clinical data. former divided into two abnormal categories, those showing AD change vascular respectively, normal group....
Four historical convergences are identified in the history of erotomania. According to first, which lasted from Classical times early eighteenth century, erotomania was a 'general disease caused by unrequited love'. second, 'excessive physical love (nymphomania)'; this view remained active well into nineteenth century. The third convergence focuses on that is form 'mental disorder', and held throughout twentieth fourth current definition (a development stage) sees as 'the delusional belief...
We perform numerical simulations of an active fully flexible self-avoiding polymer as a function the quality embedding solvent described in terms effective monomer-monomer interaction. Specifically, by extracting Flory exponent under different conditions, we are able to pin down location coil-globule transition for strength forces. Remarkably, find that simple rescaling temperature is capable qualitatively capture dependence $\Theta$-point with amplitude fluctuations. discuss limits this...
Previous studies of patients with primary osteoarthrosis the hip have suggested an increase in bone mass compared control populations. Nodal generalised is known to a strong familial tendency. To test hypothesis that this tendency might also lead increased mass, total body calcium has been measured by in-vivo neutron activation analysis and cortical area calculated from measurements metacarpal indices 15 female osteoarthrosis. The results those 12 healthy controls matched for age, menopausal...
The annual rate of bone loss in rheumatoid arthritis (RA) and primary generalized osteoarthrosis (PGOA) was determined by measurement total body calcium (TBCa). mean 24 patients with RA treated nonsteroidal anti-inflammatory drugs (NSAIDs) alone 3.4%. This not reduced ten responding to suppressive antirheumatic (4.3%) or seven receiving oral supplements (4.5%). TBCa 19 PGOA 1.6%, a figure which probably represents age-associated loss. significantly less than that corticosteroids. change 30...