Nuno André da Silva

ORCID: 0000-0003-4216-2107
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About
Contact & Profiles
Research Areas
  • Advanced MRI Techniques and Applications
  • Medical Imaging Techniques and Applications
  • Radiomics and Machine Learning in Medical Imaging
  • Functional Brain Connectivity Studies
  • Advanced Neuroimaging Techniques and Applications
  • Migraine and Headache Studies
  • MRI in cancer diagnosis
  • Microwave Imaging and Scattering Analysis
  • Chronic Disease Management Strategies
  • Vestibular and auditory disorders
  • Ultrasound Imaging and Elastography
  • Machine Learning in Healthcare
  • Lanthanide and Transition Metal Complexes
  • Artificial Intelligence in Healthcare
  • Glioma Diagnosis and Treatment
  • Surgical Simulation and Training
  • Scheduling and Optimization Algorithms
  • Spacecraft Dynamics and Control
  • Augmented Reality Applications
  • Atomic and Subatomic Physics Research
  • Soil Moisture and Remote Sensing
  • Business Process Modeling and Analysis
  • Wireless Body Area Networks
  • Underwater Vehicles and Communication Systems
  • Guidance and Control Systems

Hospital da Luz
2018-2025

Université Paris Nanterre
2022

Université Paris 8
2022

Forschungszentrum Jülich
2012-2020

INESC TEC
2016

Efacec (Portugal)
2016

Energias de Portugal (Portugal)
2016

University of Lisbon
2012-2015

National Laboratory of Energy and Geology
2013

Abstract This study presents a workflow for identifying and characterizing patients with Heart Failure (HF) multimorbidity utilizing data from Electronic Health Records. Multimorbidity, the co-occurrence of two or more chronic conditions, poses significant challenge on healthcare systems. Nonetheless, understanding multimorbidity, including most common disease interactions, risk factors, treatment responses, remains limited, particularly complex heterogeneous conditions like HF. We conducted...

10.1186/s12911-024-02497-0 article EN cc-by BMC Medical Informatics and Decision Making 2024-04-15

Phenotyping, the process of systematically identifying and classifying conditions within clinical data, is a crucial first step in any data science work involving Electronic Health Records (EHRs). Traditional approaches require extensive manual annotation efforts face challenges with scalability. We investigated use Large Language Models (LLMs) for zero-shot phenotyping 20 prevalent chronic based on synthetic patient summaries generated from real structured EHRs codes. evaluated performance...

10.1016/j.compbiomed.2025.110181 article EN cc-by-nc-nd Computers in Biology and Medicine 2025-04-23

A doença falciforme é um grupo de doenças hereditárias, decorrente da mutação monogênica, na cadeia ß-globínica hemoglobina. Atualmente, o tratamento não farmacológico proposto constituído suplementos aminoácidos por via oral ou intravenosa. Objetivo: avaliar os efeitos suplementação com arginina em portadores falciforme, diferentes faixas etárias. Metodologia: revisão narrativa busca artigos nas bases dados Pubmed, Scopus, Scielo e Lilacs, publicações dos últimos 11 anos, sendo excluídos...

10.36557/2674-8169.2025v7n5p700-713 article PT Brazilian Journal of Implantology and Health Sciences 2025-05-15

In order to benefit from the increased spectral bandwidth at ultrahigh field (UHF), use of parallel transmission (pTx) mitigate flip-angle inhomogeneity in chemical exchange saturation transfer (CEST) imaging is investigated.A pTx basis pulse homogenised by magnitude least-squares (MLS) optimization and expanded form a frequency-selective for CEST. The was simulated with three-pool Bloch-McConnell equation evaluate impact on CEST contrast. vivo performance (7 T) standard Gaussian circularly...

10.1002/mrm.26624 article EN Magnetic Resonance in Medicine 2017-02-28

To develop an open-source prototype of myocardial T1 mapping (Open-MOLLI) to improve accessibility cardiac and evaluate its repeatability. With Open-MOLLI, we aim enable faster implementation testing sequence modifications facilitate inter-scanner cross-vendor reproducibility studies.

10.1002/mrm.30080 article EN cc-by-nc-nd Magnetic Resonance in Medicine 2024-03-25

Building on the success of positron emission tomography (PET)/CT scanners, a hybrid imaging technology, combining PET with versatile attributes magnetic resonance (MRI), has been in use for over ten years. At Forschungszentrum Jülich, one four prototypes available worldwide, commercial 3T MRI newly developed BrainPET insert, was installed 2008, allowing simultaneous data acquisition and MRI. Here, we report our ten-year-long experience methods technology through this paper numerous patients...

10.1109/trpms.2018.2863953 article EN IEEE Transactions on Radiation and Plasma Medical Sciences 2018-08-09

The deployment of offshore wind parks face several challenges. Among them are the difficulties introduced by atmospheric and sea conditions in accessing those parks. A window opportunity is a timeframe when weather acceptable enable to perform specific tasks installation operation/maintenance park. This study identifies typical time periods windows access three Portuguese maritime regions. accessibility also take into account system type transportation method for local access, namely, rubber...

10.1260/0309-524x.37.3.257 article EN cc-by Wind Engineering 2013-06-01

10.1016/j.nima.2012.08.030 article EN Nuclear Instruments and Methods in Physics Research Section A Accelerators Spectrometers Detectors and Associated Equipment 2012-08-23

Microwave imaging (MWI) has been studied as a complementary modality to improve sensitivity and specificity of diagnosis axillary lymph nodes (ALNs), which can be metastasized by breast cancer. The feasibility such system is based on the dielectric contrast between healthy ALNs. However, reliable information anatomically realistic numerical models matching properties region ALNs, are crucial develop MWI systems, still limited in literature. purpose this work methodology infer structures from...

10.1002/mp.15143 article EN Medical Physics 2021-08-02

The consensus for the clinical implementation of arterial spin labeling (ASL) perfusion imaging recommends a segmented 3D Gradient and Spin-Echo (GRASE) readout optimal signal-to-noise-ratio(SNR). correction associated susceptibility-induced geometric distortions has been shown to improve diagnostic precision, but its impact on ASL data not systematically assessed it is consistently part pre-processing pipelines. Here, we investigate effects distortion by pseudo-continuous (pCASL) with GRASE...

10.1016/j.mri.2023.06.010 article EN cc-by-nc-nd Magnetic Resonance Imaging 2023-06-19

Abstract Advanced perfusion‐weighted imaging (PWI) methods that combine gradient echo (GE) and spin (SE) data are important tools for the study of brain tumours. In PWI, single‐shot, EPI‐based have been widely used due to their relatively high speed. However, when with increasing spatial resolution, single‐shot EPI often show limitations in whole‐brain coverage multi‐contrast applications. To overcome this limitation, work employs a new version keyhole (EPIK) provide five echoes: two GEs,...

10.1002/hbm.24537 article EN Human Brain Mapping 2019-02-13

Background Echo planar imaging (EPI) is one of the methods choice in dynamic susceptibility contrast MRI (DSC‐MRI) because it provides a sufficient temporal resolution. However, relatively long readout duration EPI often imposes limitations on increased spatial coverage or use multiple contrasts. Purpose To develop DSC‐MRI method using EPIK (EPI with keyhole) to provide dual‐contrast (TE 1 and TE 2 ) information higher than EPI. compare results from community‐standard proposed method. Study...

10.1002/jmri.26639 article EN Journal of Magnetic Resonance Imaging 2019-01-08

The Multimodal Imaging Brain Connectivity Analysis (MIBCA) toolbox is a fully automated all-in-one connectivity analysis that offers both pre-processing, connectivity, and graph theory of multimodal images such as anatomical, diffusion, functional MRI, PET. In this work, the MIBCA functionalities were used to study Alzheimer's Disease (AD) in MR/PET approach. Materials Methods: Data from 12 healthy controls, 36 patients with EMCI, LMCI AD (12 for each group) obtained Neuroimaging Initiative...

10.1109/tns.2015.2417764 article EN cc-by IEEE Transactions on Nuclear Science 2015-05-08

The goal of this study is to explore the potential Optical See-Through Augmented Reality (OST-AR) in training median and paramedian epidural anaesthesia administration. To end, we propose EpiduralLens, an needle insertion simulator that augments space by resorting a dummy, HoloLens, AR target, 3D sound feedback, voice commands. proposed system projects relevant anatomical information visual guides are placed on around which complemented with aural feedback instruction process. EpiduralLens...

10.1080/21681163.2021.2012833 article EN Computer Methods in Biomechanics and Biomedical Engineering Imaging & Visualization 2021-12-21

Microwave Imaging (MWI) is an emerging medical imaging technique, which has been studied to aid breast cancer diagnosis in the frequency range from 0.5 30 GHz. The information about dielectric properties of each tissue essential assess viability this type systems. However, accurate measurements heterogeneous tissues can be very challenging, and current available still limited. In paper, we present a methodology for extracting create anatomical models axillary region. These will used MWI...

10.23919/eucap48036.2020.9135980 article EN 2022 16th European Conference on Antennas and Propagation (EuCAP) 2020-03-01

This paper deals with a spacecraft autonomous rendezvous in targeted elliptical orbit. Spacecrafts like European ATV or Japanese HTV are automated but not fully autonomous. One focuses particular on guidance and control algorithms whose main guidelines based ones. The implemented techniques presented hereafter were developed the frame of in-house studies. presents alternatives to classical Clohessy Wiltshire deal orbits, consequent its performances. Robust also identified analyzed for each...

10.2514/6.2007-6355 article EN AIAA Guidance, Navigation, and Control Conference and Exhibit 2007-06-15

Abstract Background The benefits of physical activity (PA) and adequate sleep are well documented, their importance strengthens with the increasing prevalence chronic diseases multimorbidity (MM). Interventions to promote that use commercial trackers may be useful non-pharmacological approaches managing individual health; however, limited evidence exists on improve in older adult patients MM. Methods This study aims measure effects behavioral change techniques (BCTs) delivered by a wearable...

10.1186/s12877-023-04511-y article EN cc-by BMC Geriatrics 2023-12-14
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