A5072650851- Advanced Biosensing Techniques and Applications
- Gene expression and cancer classification
- Vehicle Dynamics and Control Systems
- Monoclonal and Polyclonal Antibodies Research
- Advanced biosensing and bioanalysis techniques
- Catalytic Processes in Materials Science
- MicroRNA in disease regulation
- Quantum Dots Synthesis And Properties
- CRISPR and Genetic Engineering
- Catalysis and Oxidation Reactions
- Microfluidic and Capillary Electrophoresis Applications
- Electric and Hybrid Vehicle Technologies
- Semiconductor Quantum Structures and Devices
- Traffic control and management
- Perovskite Materials and Applications
- Innovative Microfluidic and Catalytic Techniques Innovation
- Industrial Technology and Control Systems
- Mechanical Engineering and Vibrations Research
- Simulation and Modeling Applications
- RNA and protein synthesis mechanisms
- Semiconductor Lasers and Optical Devices
- Vehicle emissions and performance
- Catalysts for Methane Reforming
- Cancer-related molecular mechanisms research
- Autonomous Vehicle Technology and Safety
Nanjing University of Aeronautics and Astronautics
2019-2025
Shandong University of Traditional Chinese Medicine
2025
Shanghai Academy of Spaceflight Technology
2024
Jilian Technology Group (China)
2024
Delft University of Technology
2023
Chongqing University of Technology
2022
Xi'an Jiaotong University
2021
Shanghai Jiao Tong University
2019-2021
Wuhan Textile University
2019
Lone Star College
2009-2016
Breast milk is a complex liquid rich in immunological components that affect the development of infant's immune system.Exosomes are membranous vesicles endocytic origin found various body fluids and can mediate intercellular communication.Mi-croRNAs (miRNAs), well-defined group non-coding small RNAs, packaged inside exosomes human breast milk.Here, we identified 602 unique miRNAs originating from 452 miRNA precursors (pre-miRNAs) using deep sequencing technology.We that, out 87...
More complete knowledge of the molecular mechanisms underlying cancer will improve prevention, diagnosis and treatment. Efforts such as The Cancer Genome Atlas are systematically characterizing structural basis cancer, by identifying genomic mutations associated with each type. A powerful complementary approach is to characterize functional genes essential for growth related phenotypes in different cells. Such information would be particularly valuable potential drug targets. Here, we report...
The domestic pig is of enormous agricultural significance and valuable models for many human diseases. Information concerning the microRNAome (miRNAome) has been long overdue elucidation this information will permit an atlas microRNA (miRNA) regulation functions networks to be constructed. Here we performed a comprehensive search porcine miRNAs on ten small RNA sequencing libraries prepared from mixture tissues obtained during entire lifetime, fetal period through adulthood. results were...
Background: MicroRNAs (miRNAs), a large family of short endogenous RNAs known to post-transcriptionally repress gene expression, participate in the regulation almost every cellular process.Changes miRNA expression are associated with many pathologies.Ovarian folliculogenesis and testicular spermatogenesis complex coordinated biological processes, which tightly regulated interaction multitude genes could be by these miRNAs.Identification preliminary characterization gonad-specific miRNAs...
An all-solution processed inverted green quantum dot-based light-emitting diode with concurrent high efficiency and long lifetime is obtained by precisely controlled double shell growth of dots.
Oligonucleotide microarrays or oDNA chips are effective decoding and analytical tools for genomic sequences useful a broad range of applications. Therefore, it is desirable to have synthesis methods DNA that highly flexible in sequence design provide high quality general adoptability. We report herein, microarray based on biochip method. Our method simply uses photogenerated acid (PGA) solution trigger deprotection the 5′-OH group conventional nucleotide phosphoramidite monomers (i.e....
There is substantial interest in implementing a bioinformatics tool that allows the design of oligonucleotides to support development vitro gene synthesis. Current protocols make long synthetic DNA molecules rely on assembly set short oligonucleotides, either by ligase chain reaction (LCR) or PCR. Ideally, such should represent both strands final molecule. They be adjacent same strand and overlap complementary from second ensure good hybridization during assembly. This implies thermodynamic...
Large DNA constructs of arbitrary sequences can currently be assembled with relative ease by joining short synthetic oligodeoxynucleotides (oligonucleotides). The ability to mass produce these genes readily will have a significant impact on research in biology and medicine. Presently, high-throughput gene synthesis is unlikely, due the limits oligonucleotide synthesis. We describe microfluidic PicoArray method for simultaneous purification oligonucleotides that are designed multiplex Given...
Blue ZnSe/ZnS/ZnS quantum dots were prepared using a seed-mediated and double shell strategy, the dot-based light-emitting diode with electroluminescence spectrum peaked at 446 nm full widths half-maximum of 16 was fabricated.
Abstract Lead‐based perovskite nanocrystals (NCs) are promising candidates for use in lighting and display applications; however, the toxicity of lead is one critical issue that needs to be solved its commercialization. Consequently, less toxic tin bismuth‐based NCs have been developed, but these materials exhibit low photoluminescence quantum yields (PLQYs) large full width at half maximum (FWHM) values. Due their similarity size Eu 2+ Pb , more environmental‐friendly europium shows...
Solution reactions using photogenerated reagents (Gao, X.; Yu, P.; LeProust, E.; Sonigo, L.; Pellois, J. Zhang, H. Am. Chem. Soc. 1998, 120, 12698) are a potentially powerful means for combinatorial parallel synthesis of addressable molecular microarrays. In this report, we demonstrate that chemistry permits screening reaction conditions on microarray platform. Using method optimization and our apparatus, efficient acids suitable removal the acid labile protection group 5'-O nucleotides...
BackgroundMicroRNAs (miRNAs: a class of short non-coding RNAs) are emerging as important agents post transcriptional gene regulation and integral components networks. MiRNAs have been strongly linked to stem cells, which remarkable dual role in development. They can either continuously replenish themselves (self-renewal), or differentiate into cells that execute limited number specific actions (pluripotence).Methodology/Principal FindingsIn order identify novel miRNAs from narrow windows...
Abstract Four-Wheel Independent Steering (4WIS) Vehicles can independently control the angle of each wheel, demonstrating superior trajectory tracking performance under normal conditions. However, on intermittent icy and snowy roads, presence time-varying adhesion coefficients, cornering stiffness, irregularities due to ice snow accumulation introduce multiple uncertainties into steering system, significantly degrading 4WIS vehicles. In response, this paper proposes a robust Tube Model...
Abstract Peptide and peptidomimetic molecule arrays are emerging powerful tools for parallel screening of binding in proteomics pharmaceutical discovery research. Up to now the common method preparing peptide was based on spotting glass using a library presynthesized peptides. However, due large number monomers (amino acids) it is not possible have combinatorial libraries which include all combinations natural synthetic amino acids. We describe very flexible on‐chip oligopeptide synthesis...