A5065729404- Aquaculture Nutrition and Growth
- Heavy Metal Exposure and Toxicity
- Heavy Metals in Plants
- Natural Antidiabetic Agents Studies
- Aquaculture disease management and microbiota
- Paraoxonase enzyme and polymorphisms
- Phytochemistry and biological activity of medicinal plants
- Environmental Toxicology and Ecotoxicology
- Phytochemistry and Biological Activities
- Selenium in Biological Systems
- Phytochemicals and Antioxidant Activities
- Pomegranate: compositions and health benefits
- Complementary and Alternative Medicine Studies
- Adipose Tissue and Metabolism
- Pharmacological Effects of Medicinal Plants
- Skin Protection and Aging
- Immune Response and Inflammation
- Hepatitis B Virus Studies
- Bone Metabolism and Diseases
- Glutathione Transferases and Polymorphisms
- Nigella sativa pharmacological applications
- Carcinogens and Genotoxicity Assessment
- Bone health and osteoporosis research
- Advanced Glycation End Products research
- Estrogen and related hormone effects
Van Yüzüncü Yıl Üniversitesi
2015-2024
Bolu Abant İzzet Baysal University
2021-2022
Mersin Üniversitesi
2008-2017
Cukurova University
2011
Aim: Major side effects of cyclophosphamide administration are immunosuppression and myelosuppression. The immunomodulatory plant bioactive compounds on chemotherapy drug-induced may have significant in cancer treatment. For this reason, we investigated the effect myricetin, apigenin, hesperidin cyclophosphamide-induced rats.Methods: In our study, a total 64 rats were used, divided into eight equal groups. These groups were: control, cyclophosphamide, + myricetin (100 mg/kg), (200 apigenin...
The genotoxic effects of sublethal doses cadmium in peripheral erythrocytes Oreochromis niloticus was investigated using micronucleus (MN) and nuclear abnormalities (NAs) tests. For this reason, the fish were exposed to medium changes 0.5 1.0 mg/L (Cd) during an average treatment period 10 days. On 2nd, 4th, 6th, 10th days test period, erythrocytes, including micronuclei other such as lobbed nuclei (LB), blebbed (BL), notched (NT), counted pointed out. As a positive control, 4 dose...
Lung cancer is the most common cause of cancer-related deaths worldwide.Punicalagin an ellagitannin mostly found in pomegranate husk and shows very strong antitumoral activity.The purpose this study was to investigate mechanism which punicalagin acts as antiproliferative agent on A549 cell line (adenocarcinomic human alveolar basal epithelial cells) MRC-5 (normal lung fibroblast cells).The cultured cells were treated with at concentrations 1-100 μM for 24 h.For aim, growth inhibition,...
Cornelian cherry ( Cornus mas ) is a valuable source of phenolic antioxidants. Flavonoid derivatives as nonenzymatic antioxidants are important in the pathophysiology many diseases including neurological disorders (e.g., Alzheimer’s disease) or heart disease. In this study, we examined effect an addition freeze-dried fruit cornelian on three types diets: control diet, fructose and diet enriched fats (high-fat diet). This was studied by determining following antioxidant parameters both brain...
Diosmin is an unsaturated flavonoid glycoside, presents in citrus fruits.The aim of this study to investigate the molecular mechanism diosmin with respect NF-κB and MAPKs signaling pathways.Firstly, 10, 20, 30, 40 50 µM were treated lipopolysaccharide (LPS)-stimulated RAW264.7 macrophages.The anti-inflammatory effects was displayed via measuring prostaglandin E 2 (PGE ), nitric oxide (NO), interleukines (IL-6, IL-12), tumor necrosis factor α (TNF-α) production, cyclooxygenase-2 (COX-2),...
BACKGROUND:Use of a hookah (a type water pipe) is traditional way smoking tobacco, particularly in the Middle East. In Turkey, its popularity has been growing recent years, especially among young people. It known that cigarette genotoxic effects and causes mutations, but no comprehensive study done on usage, Turkey. MATERIAL AND METHODS:We collected peripheral blood/buccal smear samples from 30 subjects who did not smoke cigarettes regularly an average 2 times per week, control had never...
This 60 day study investigated the effects of organically certified nucleotide yeast-derived protein source (Nu-Pro®) on growth, feed efficiency, fillet proximate composition and digestive enzymes in rainbow trout (Onchorhyncus mykiss). Diets were isonitrogenous isocaloric. Three experimental diets wherein 20%, 40% 60% fish meal content was replaced by Nu-Pro®, compared to control diet which crude anchovy corn gluten meal. The (initial weight 27 g/fish) fed twice daily 200-l Aqaria. Live...
Aim/Purpose of the study:Inhibition microglial activation using phytochemicals may be a potential candidate for prevention neurodegenerative diseases caused by neuroinflammation and oxidative stress. The goal this study was to investigate protective role Biochanin A on lipopolysaccharide (LPS)-stimulated BV2 cells. cells were treated with LPS in presence absence A. Materials methods: For aim, nitric oxide production, nuclear factor kappa B (NF-κB), tumor necrosis alpha (TNF-α), interleukin-1...
Studies related to the toxicological risk assessment (TRA) of heavy metal impurities (HMIs) in pharmaceuticals are an important issue but there is a lack refereed literature around safety Valeriana officinalis L., radix (Valerian root) as herbal medicinal product (HMP) for relief mild nervous tension and sleep disorders according lead cadmium impurities. The aim study was estimate TRA HMP (n = 5) available Polish pharmacies. In case pharmaceuticals, it particularly control level HMIs...
Background: Alcohol use disorder (AUD) is a chronic relapsing associated with compulsive drinking of alcohol. Natural flavonoid fisetin affects variety transmitter systems relevant to AUD, such as aminobutyric acid, N-methyl-D-aspartate, and dopamine, well peroxisome proliferator-activated receptors.
Abstract Objectives: This study aimed to explore the effects of curcumin on experimental allergic rhinitis in rats. Methods: Twenty-eight male Wistar albino rats were randomly divided into four groups: a control group; group which was induced and no treatment given; followed by with azelastine hydrochloride days 21–28; 21–28. Allergy symptoms histopathological features nasal mucosa examined. Results: The sneezing congestion scores higher groups than group. Histopathological examination...
The present study investigated the effects of prebiotic inulin on growth parameters, digestive enzyme activities and antioxidant status rainbow trout (Oncorhynchus mykiss). After acclimation, fish (34±0.22 g; n = 135) were assigned into 9 tanks (15 per tank) triplicate groups fed a control diet (G-0) or diets containing 1% (G-1) 2% (G-2) inulin. At end trial (8 weeks), factors (final weight, weight gain, specific rate (SGR), food conversion ratio (FCR), protein efficiency (PER), Economic...