1) Investigate the impact of electrode type and surgical approach on scalar location; 2) examine relation between location postoperative audiologic performance.Tertiary academic hospital.Two hundred twenty post-lingually deafened adults undergoing cochlear implant (CI).Primary outcome measures interest were performance.In 68% implants, electrodes observed to be located solely in scala tympani (ST). Multivariate analysis demonstrated perimodiolar (PM) mid-scala (MS) 22.4 (95% CI: 6.3-80.0, p...

To characterize the physiologic nature of vestibular dysfunction that occurs with normative aging process.Cross-sectional study.Tertiary care academic medical center.Fifty individuals age 70 years and above.Head thrust dynamic visual acuity testing cervical ocular vestibular-evoked myogenic potential (VEMP) testing.Semicircular canal function measured by head in each 3 semicircular planes, saccular utricular VEMP testing, respectively.We observed significant declines planes as well otolith...

Objectives To determine whether cervical vestibular evoked myogenic potential (cVEMP) thresholds or ocular VEMP (oVEMP) amplitudes are more sensitive and specific in the diagnosis of superior semicircular canal dehiscence syndrome (SCDS). Study Design Prospective case-control study. Setting Tertiary referral center. Subjects Methods Twenty-nine patients with SCDS (mean age 48 yr; range, 31–66 yr) 25 age-matched controls 30–66 yr). Intervention(s) cVEMP oVEMP response to air-conducted sound....

To describe the incidence, clinical presentation, and performance of cochlear implant (CI) recipients with tip fold-over.Retrospective case series.Tertiary referral center.CI who underwent postoperative computed tomography (CT) scanning.Tip fold-over was identified tomographically using previously validated software that identifies electrode array. Electrophysiologic testing including spread excitation or electric field imaging (EFI) measured on those fold-over.Location fold-over;...

To characterize both cervical and ocular vestibular-evoked myogenic potential (cVEMP, oVEMP) responses to air-conducted sound (ACS) midline taps in Ménière disease (MD), vestibular migraine (VM), controls, as well determine if cVEMP or oVEMP can differentiate MD from VM.Prospective cohort study.Tertiary referral center.Unilateral definite patients (n = 20), VM 21) by modified Neuhauser criteria, age-matched controls 28). testing used ACS (clicks), (clicks 500-Hz tone bursts) tap stimuli...

First, to define the best single-step suprathreshold screening test for superior canal dehiscence syndrome (SCDS); second, obtain further insight into relative sensitivity of vestibular afferents sound vibration in presence a dehiscence.Prospective study.Tertiary referral center.Eleven patients with surgically confirmed SCDS (mean, 50 yr; range, 32-66 yr) and 11 age-matched, healthy subjects (right ear only) no hearing or deficits 33-66 yr).All completed ocular cervical evoked myogenic...

1) Describe the association between hearing loss and dysfunction of each 5 vestibular end-organs--the horizontal, superior, posterior semicircular canals; saccule; utricle--in older individuals. 2) Evaluate whether end-organ deficits share any risk factors.

Multi-slice computed tomography (MSCT) overestimates the size of superior semicircular canal dehiscences (SSCDs) and also can misinterpret thin bone over as dehiscent. A threshold radiodensity may exist that could optimize prediction an actual SSCD.The gold standard for diagnosis SSCD is MSCT, but there a higher prevalence based on MSCT compared with histologic studies. Overestimation lead to inappropriate treatment.We correlated radiographic surgical findings in determine if overestimated...

Hypothesis: Cochlear duct length (CDL) can be automatically measured for custom selection of cochlear implant (CI) electrode arrays. Background: CI array influenced by measuring the CDL, which is estimated based on line that connects round window and lateral wall cochlea when passing through modiolus. CDL measurement remains time consuming inter-observer variability has not been studied. Methods: We evaluate an automatic approach to directly measure two-turn (2T) using existing algorithms...

Objectives (1) To describe and review a single center’s pediatric endoscopic cholesteatoma experience, including surgical audiologic outcomes. (2) assess the most common locations of residual following removal. Study Design Case series with chart review. Setting Tertiary otologic referral center. Subjects Patients <19 years age who underwent removal either or microscopic visualization. Methods In comparison patients total ear surgery (TEES), combined endoscopic‐microscopic surgery,...

To assess the prevalence of vestibular dysfunction in older adults using head impulse test (HIT) and to independent influence HIT abnormalities on gait speed fall risk individuals.Cross-sectional study.Tertiary care academic medical center.Fifty community-dwelling individuals age 70 older.HIT (abnormal defined as right or left abnormality), visual acuity, monofilament testing, grip strength.Gait a 4-meter walk history falls (including number falls) last 1 5 years.The participants' mean was...

Objective Previous observational studies suggest higher rates of vestibular dysfunction among patients with type 2 diabetes mellitus (DM) compared those without diabetes. This study aims to functionally localize in adults DM. Study Design Prospective cohort study. Setting Tertiary academic medical center. Subjects and Methods Adults 50 years age older ≥10‐year history DM were recruited (December 2011–February 2013, n = 25). Vestibular function was assessed by cervical ocular...

Objectives To investigate intra‐ and postoperative outcomes of endoscopic stapes surgery. Study Design Case series with chart review. Setting Four tertiary care otologic centers. Subjects Methods Sixty‐five subjects 18 years older who underwent surgeries were analyzed. Variables analyzed included surgical techniques intraoperative findings. Outcomes measured hearing complications to date. Results Fifty‐one patients met inclusion exclusion criteria. The average patient age was 48.1 (range,...

To investigate the efficacy of a perioperative oral steroid taper on low-frequency hearing preservation after cochlear implantation.Retrospective case series.Tertiary referral center.Consecutive implant recipients between January 2012 and December 2014 who were candidates for approach based preoperative pure tone thresholds identified.A subgroup patients received 2-week corticosteroid beginning 3 days before surgery. All implanted using standard length electrodes.The first postoperative...

We have compared the lateral diffusion of intact transmembrane proteins, wild-type H-2Ld antigens, with that mutants truncated in cytoplasmic domain. Diffusion coefficients and mobile fractions were similar for all molecules examined, from Ld antigens 31 residues on side plasma membrane to only four This result limits ways which a major histocompatibility antigen, protein, can be constrained by interactions other molecules.

Conclusion: As a bedside test of subjective visual vertical (SVV), the 'bucket test' has role as viable and cost-effective clinical unilateral utricular dysfunction in older individuals. Objective: To investigate whether bucket SVV is valid function Methods: This was diagnostic validation study at tertiary academic medical center. Vestibular evaluated using sound-evoked cervical tap-evoked ocular vestibular evoked myogenic potential (cVEMP oVEMP, respectively) asymmetry ratios, SVV,...

Abstract Purpose Automated insertion of electrode arrays (EA) in cochlear implant surgery is presumed to be less traumatic than manual insertions, but no tool widely available the operating room. We sought (1) design and create a simple able automate EA process; (2) perform preliminary evaluations designed prototype. Methods A first prototype with maximum simplicity was fabricated take advantage hydraulic actuation. The facilitates automated forward motion using syringe connected an infusion...

The present study sought to 1) characterize insertion forces resulting from a flexible straight electrode array (EA) inserted at slow and ultra-slow velocities, 2) evaluate if velocities decrease independent of other variables.Low are desirable in cochlear implant (CI) surgery reduce trauma preserve hearing. Recently, (lower than manually feasible) have been shown produce significantly lower using EAs.Five EAs were used record into an inelastic artificial scala tympani model. Eleven trial...

<h3>Objective</h3>To characterize (1) the impairment and recovery of functional balance (2) extent vestibular dysfunction physiological compensation following superior canal dehiscence syndrome (SCDS) surgical repair.<h3>Design</h3>Prospective study.<h3>Setting</h3>Tertiary referral center.<h3>Participants</h3>Thirty patients diagnosed as having SCDS.<h3>Interventions</h3>Surgical plugging resurfacing SCDS.<h3>Main Outcome Measures</h3>Balance measures were assessed in 3 separate groups,...

To identify predictors of near dehiscence (ND) or thin rather than dehiscent bone overlying the superior semicircular canal in patients with signs and symptoms suggestive syndrome (SCDS), as well postoperative outcomes.Retrospective case-control study.Tertiary referral center.All 288 who underwent middle cranial fossa approach for repair SCDS (1998-2018) were reviewed cases ND. Demographics, symptoms, clinical including nystagmus, ocular vestibular-evoked myogenic potential (oVEMP)...

&lt;b&gt;&lt;i&gt;Objective:&lt;/i&gt;&lt;/b&gt; To compare the sensitivity and specificity of ocular vestibular evoked myogenic potentials (oVEMPs) using 2 electrode montages for diagnosis superior canal dehiscence syndrome (SCDS). &lt;b&gt;&lt;i&gt;Subjects:&lt;/i&gt;&lt;/b&gt; 16 SCDS patients (17 affected-SCDS ears, 15 contralateral-SCDS ears) 12 controls (24 ears). &lt;b&gt;&lt;i&gt;Methods:&lt;/i&gt;&lt;/b&gt; oVEMPs were recorded in response to 500-Hz tone bursts montages. For both...