A5060257019- Meningioma and schwannoma management
- Ear Surgery and Otitis Media
- Neurofibromatosis and Schwannoma Cases
- Hearing Loss and Rehabilitation
- Hearing, Cochlea, Tinnitus, Genetics
- Ear and Head Tumors
- Vestibular and auditory disorders
- Head and Neck Surgical Oncology
- Facial Nerve Paralysis Treatment and Research
- Noise Effects and Management
- Salivary Gland Tumors Diagnosis and Treatment
- Vascular Malformations Diagnosis and Treatment
- Cerebral Venous Sinus Thrombosis
- Tracheal and airway disorders
- Diversity and Career in Medicine
- Bone Tumor Diagnosis and Treatments
- Hearing Impairment and Communication
- Adrenal and Paraganglionic Tumors
- Ophthalmology and Eye Disorders
- Voice and Speech Disorders
- Speech and Audio Processing
- Traumatic Brain Injury and Neurovascular Disturbances
- Pituitary Gland Disorders and Treatments
- Delphi Technique in Research
- Sinusitis and nasal conditions
The University of Texas Southwestern Medical Center
2017-2025
Thomas Jefferson University Hospital
2023-2025
Thomas Jefferson University
2023-2025
Southwestern Medical Center
2018-2025
Taipei City Government
2023-2024
Temple University
2023-2024
American Academy of Otolaryngology — Head and Neck Surgery
2023-2024
Harvard University
2023-2024
University of California, Los Angeles
2004-2023
City University of Seattle
2023
1) Investigate the impact of electrode type and surgical approach on scalar location; 2) examine relation between location postoperative audiologic performance.Tertiary academic hospital.Two hundred twenty post-lingually deafened adults undergoing cochlear implant (CI).Primary outcome measures interest were performance.In 68% implants, electrodes observed to be located solely in scala tympani (ST). Multivariate analysis demonstrated perimodiolar (PM) mid-scala (MS) 22.4 (95% CI: 6.3-80.0, p...
Objectives 1) Examine angular insertion depths (AID) and scalar location of Med‐El (GmbH Innsbruck, Austria) electrodes; 2) determine the relationship between AID audiologic outcomes controlling for position. Study Design Retrospective review. Methods Postlingually deafened adults undergoing cochlear implantation with Flex 24, 28, Standard electrode arrays (Med‐El) were identified. Patients preoperative postoperative computed tomography scans included so that could be determined. Outcome...
Objectives/Hypothesis The aims of this study were to i nvestigate short‐ and long‐term rates hearing preservation after cochlear implantation identify factors that impact preservation. Study Design Retrospective review. Methods Patients undergoing with conventional‐length electrodes air‐conduction thresholds ≤80 dB HL at 250 Hz preoperatively included. Hearing was defined as Hz. Results sample included 196 patients (225 implants). Overall, the rate short‐term 38% (84/225), 18% (33/188)...
To characterize the risk and predictors of growth during observation vestibular schwannomas (VS).Retrospective case series.Single academic, tertiary care center.Five hundred sixty-four consecutive VS patients who underwent at least two magnetic resonance imaging (MRI) studies before intervention.Serial MRI studies.Tumor growth, defined as a ≥2 mm increase in maximum tumor diameter between studies, or first last study.A total 1296 (1995-2015) with were identified. Of those, 564 (median age...
Hypothesis: Cochlear duct length (CDL) can be automatically measured for custom selection of cochlear implant (CI) electrode arrays. Background: CI array influenced by measuring the CDL, which is estimated based on line that connects round window and lateral wall cochlea when passing through modiolus. CDL measurement remains time consuming inter-observer variability has not been studied. Methods: We evaluate an automatic approach to directly measure two-turn (2T) using existing algorithms...
1) Compare rates of scala tympani (ST) insertion between Nucleus CI422 Slim Straight electrodes and CI512 Contour Advance electrodes; 2) examine audiometric performance with both electrode arrays, while controlling for location.Tertiary academic hospital.Fifty-six post-lingually deafened adults undergoing cochlear implant (CI).Primary outcome measures interest were scalar location postoperative audiologic performance.Fifty-six implants in 49 patients included; 20 implanted electrodes, 36...
Objectives (1) To describe and review a single center’s pediatric endoscopic cholesteatoma experience, including surgical audiologic outcomes. (2) assess the most common locations of residual following removal. Study Design Case series with chart review. Setting Tertiary otologic referral center. Subjects Patients <19 years age who underwent removal either or microscopic visualization. Methods In comparison patients total ear surgery (TEES), combined endoscopic‐microscopic surgery,...
Objective To determine the sensitivity and specificity of ocular cervical vestibular evoked myogenic potentials (VEMPs) in diagnosis superior semicircular canal dehiscence (SCD) to describe VEMP response characteristics that are most sensitive SCD compare findings previous reports. Study Design Case series with chart review. Setting Two tertiary neurotologic referral centers. Subjects Methods Cervical peak‐to‐peak amplitudes thresholds from 39 adult patients older than 18 years surgically...
Objectives To investigate intra‐ and postoperative outcomes of endoscopic stapes surgery. Study Design Case series with chart review. Setting Four tertiary care otologic centers. Subjects Methods Sixty‐five subjects 18 years older who underwent surgeries were analyzed. Variables analyzed included surgical techniques intraoperative findings. Outcomes measured hearing complications to date. Results Fifty‐one patients met inclusion exclusion criteria. The average patient age was 48.1 (range,...
To evaluate the audiometric outcomes following endoscopic ossicular chain reconstruction (OCR).Retrospective case series.Two tertiary referral centers.Sixty two ears with discontinuity.Endoscopic and microscopic OCR in patients discontinuity.Bone air pure-tone averages (PTA), air-bone gap (ABG), word recognition scores (WRS).Sixty were included for analysis. Patients that underwent ossiculoplasty subdivided based on prosthesis type (total replacement [TORP] partial [PORP], primary staged...
To identify demographic predictors of patients undergoing cochlear implantation evaluation and surgery.Consecutive adult between 2009 2018 who underwent at a university program were retrospectively identified to determine (1) qualification rate (2) pursuit surgery with respect age, gender, race, primary spoken language, marital status, insurance type, distance the center.A total 823 evaluations analyzed. Overall, 76.3% qualified for 61.5% these pursued surgery. Age was only independent...
The current study aims to characterize the natural history of sporadic vestibular schwannoma volumetric tumor growth, including long-term growth patterns following initial detection growth.Volumetric measurements from 3505 serial MRI studies were analyzed unselected consecutive patients undergoing wait-and-scan management at three tertiary referral centers between 1998 and 2018. Volumetric was defined as a change in volume ≥20%.Among 952 observation, 622 experienced with growth-free survival...
We describe a molecular resistance biomarker to gefitinib, epithelial membrane protein-1 (EMP-1). Gefitinib is small-molecule inhibitor that competes for the ATP-binding site on EGF receptor (EGFR) and has been approved patients with advanced lung cancers. Treatment gefitinib resulted in clinical benefit patients, and, recently, heterozygous somatic mutations within EGFR catalytic domain have identified as correlate objective response gefitinib. However, limits utility of this therapeutic...
To evaluate hearing preservation (HP) outcomes in adult cochlear implant recipients with a mid-scala electrode.Tertiary academic center.Adult patients implanted electrode between May 2013 and July 2015.Cochlear implantation.Age, sex, surgical approach, residual changes post implantation, HP rates using different published classifications, speech perception scores.Fifty ears for 47 (mean age, 58.2 yr; range, 23-86) were the electrode. Recognizing that not all true candidates and/or underwent...
Objective: To investigate the efficacy and safety of endoscopic middle ear paraganglioma (glomus tympanicum) resection. Study Design: Case series with chart review. Setting: Multi-institutional tertiary university medical centers. Patients: Adult patients paragangliomas treated via a transcanal approach from 1/2012 to 11/2015. Intervention: All tumors were initially approached technique. An operating microscope was used only if tumor could not be adequately visualized or resected techniques...
Abstract Objective Limited evidence guides the optimal timing of treatment after detection tumor growth during observation sporadic vestibular schwannoma (VS). The current work aimed to inform radiosurgical intervention based on an analysis patient outcomes among those who ultimately failed stereotactic radiosurgery (SRS) and underwent salvage microsurgery. Study Design A historical cohort study. Setting Seven centers across United States Norway. Methods Adults with VS microsurgery following...
Objective To provide the first description of intratympanic bacteriophage therapy for chronic mastoiditis from multidrug-resistant Pseudomonas aeruginosa in United States. Patients A 47-year-old woman with setting ciliary dysfunction cystic fibrosis and immunosuppression lung transplantation. Interventions Ten concurrent parenteral doses two custom phages targeting P. followed by IV antibiotic therapy. Main Outcome Measures Resolution infection confirmed symptomatology, cultures, imaging....
Objective Exploring whether the utilization of implantable hearing rehabilitation devices is associated with a reduced likelihood developing delirium in patients loss. Study Design A retrospective cohort database study propensity score matching (PSM) utilizing TriNetX clinical database. Setting The US Collaborative Network within (100 million people). Patients over 55 years old were selected based on three categories: non–hearing loss control (ICD-10: H90–91), (HL without device), and an...