A5057062321- Autism Spectrum Disorder Research
- Genetics and Neurodevelopmental Disorders
- Neurofibromatosis and Schwannoma Cases
- Attention Deficit Hyperactivity Disorder
- Advanced Neuroimaging Techniques and Applications
- Fetal and Pediatric Neurological Disorders
- Face Recognition and Perception
- Functional Brain Connectivity Studies
- Williams Syndrome Research
- Technology and Human Factors in Education and Health
- Psychosomatic Disorders and Their Treatments
- Behavioral and Psychological Studies
- EEG and Brain-Computer Interfaces
- Embodied and Extended Cognition
- Neurological disorders and treatments
- Reading and Literacy Development
- Neural and Behavioral Psychology Studies
- Psychology of Development and Education
- Chromatin Remodeling and Cancer
- Child and Animal Learning Development
- Educational and Psychological Assessments
- Congenital Heart Disease Studies
- Fractal and DNA sequence analysis
- Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Child Development and Digital Technology
KU Leuven
2011-2025
Universitair Ziekenhuis Leuven
2012
Neurofibromatosis type 1 (NF1) is an autosomal dominant genetic condition. While considerable work has focused on cognitive functioning, several research groups also observed difficulties in social functioning as a prominent feature of NF1. These problems and the possible link between NF1 Autism Spectrum Disorder (ASD) have become increasingly important recent literature. The aim current study was to assess ASD characteristics hospital-based pediatric population (n = 82) using standardized...
The present study investigated differences in symptom perception between a clinical sample with medically unexplained symptoms (MUS) and matched healthy control group. Participants (N = 58, 29 patients) were told that they would inhale different gas mixtures might induce symptoms. Next, went through 2 subsequent rebreathing trials consisting of baseline (60 s room air breathing), phase (150 s, which gradually increased ventilation, PCO2 the blood, perceived dyspnea), recovery returning to...
The aim of this study was to provide a broad picture Executive Functioning (EF) in NF1 children, while taking into account their lower average IQ and increased Autism Spectrum Disorder (ASD) symptoms. This done by administering an extended battery tasks questionnaires, designed reduce task impurity, that measures five EF domains (inhibition, cognitive flexibility, working memory, generativity planning) laboratory setting daily life. Data are presented for 42 age‐ gender‐matched NF1, 52...
One of the most reported neural features autism spectrum disorder (ASD) is alteration multiple long-range white matter fiber tracts, as assessed by diffusion-weighted imaging and indexed reduced fractional anisotropy (FA). Recent methodological advances, however, have shown that this same pattern FA may be an artifact resulting from excessive head motion poorer data quality aberrant structural connectivity in children with ASD confined to right inferior longitudinal fasciculus (ILF). This...
Heterogeneity within autism spectrum disorder (ASD) hampers insight in the etiology and stimulates search for endophenotypes. Endophenotypes should meet several criteria, most important being association with ASD higher occurrence rate unaffected relatives than general population. We evaluated these criteria executive functioning (EF) local-global (L-G) visual processing.By administering an extensive cognitive battery which increases validity of measures, we examined anomalies shown by...
Impairments in visuoperceptual processing have long been considered a hallmark deficit of individuals with Neurofibromatosis type 1 (NF1). However, it is unclear which specific subprocesses are impaired and whether impairments on these tasks really result from or rather confounding factors like Executive Functioning (EF) impairments, lower intelligence (IQ) and/or co-occurring symptoms Autism Spectrum Disorder (ASD). To answer questions, we administered four two control 39 children NF1, 52...
Object recognition relies on a hierarchically organized ventral visual stream, with both bottom-up and top-down processes. Here, we aimed at investigating the neural underpinnings of perceptual organization along stream in Autism Spectrum Disorders (ASD), determining whether this would be associated decreased processing ASD. Nineteen typically developing (TD) adolescents sixteen ASD participated an fMRI study where they had to detect objects. Five conditions displayed Gabor patterns (defined...