José A. Esteban

ORCID: 0000-0003-4250-9123
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About
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Research Areas
  • Caveolin-1 and cellular processes
  • Chemokine receptors and signaling
  • Cell Adhesion Molecules Research
  • Galectins and Cancer Biology
  • Inflammation biomarkers and pathways
  • Pharmacological Effects of Natural Compounds

Centro de Biología Molecular Severo Ochoa
2024

Universidad Autónoma de Madrid
2024

Abstract Intestinal infections trigger inflammation and can contribute to degenerative cognitive brain pathologies through the microbiota-gut-brain axis. Galectin-4 is an intestinal lectin key in control of pathogenic bacterial infections. Here we report that galectin-4 deficient mice (Lgals4-KO) show altered commensal microbiota absence pathogens, defining a new role modulation bacteria. Strikingly, Lgals4-KO present memory formation, impaired hippocampal long-term potentiation (LTP) vivo...

10.1101/2024.10.14.617868 preprint EN cc-by-nc-nd bioRxiv (Cold Spring Harbor Laboratory) 2024-10-16
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