A5037041193- Mass Spectrometry Techniques and Applications
- Analytical chemistry methods development
- Analytical Chemistry and Chromatography
- Advanced Chemical Sensor Technologies
- Pesticide Residue Analysis and Safety
- Microfluidic and Capillary Electrophoresis Applications
- Plasma Applications and Diagnostics
- Metal-Organic Frameworks: Synthesis and Applications
- Effects and risks of endocrine disrupting chemicals
- Probiotics and Fermented Foods
- Analytical Chemistry and Sensors
- Electrohydrodynamics and Fluid Dynamics
- Ion-surface interactions and analysis
- Polyoxometalates: Synthesis and Applications
- Nitric Oxide and Endothelin Effects
- Bacterial biofilms and quorum sensing
- Metabolomics and Mass Spectrometry Studies
- Hemoglobin structure and function
- Porphyrin and Phthalocyanine Chemistry
- Supramolecular Chemistry and Complexes
- Spectroscopy and Laser Applications
University of Duisburg-Essen
2013-2024
Essen University Hospital
2015
A tube plasma ionization (TPI) open-air source for gas chromatography-mass spectrometry (GC-MS) was developed. This is based on an inverse low temperature configuration where the pin inner electrode applying high voltage and grounded housing itself. The possibilities were tested by using EPA mix of priority contaminants, showing that 68% analytes could undergo both proton-transfer charge-exchange reactions. potential different discharge gases (He Ar) to ionize auxiliary (He, N2, O2,...
A low-temperature plasma (LTP) was used as an ionization source for differential ion mobility spectrometry (DMS) the first time. This enhances potential of DMS a miniaturized system on-site rapid monitoring. The effects experimental parameters (e.g., discharge/carrier gas composition and flow rate, applied voltage) on analysis model aromatic compounds were investigated discussed. It found that nature reactant positive (RIP) is dependent composition. best response to analyte achieved when...
Abstract Perfluorodecalin (PFD)‐filled capsules have been studied for over 15 years as artificial oxygen carriers. However, none of these combines good biocompatibility, mechanical stability and dispersion stability. Here we propose to use synthetic triblock peptides containing a central block cysteine units cross‐linking shell material with both biocompatibility Together outer aspartate inner phenylalanine units, the resulting amphiphilic can encapsulate PFD efficiently prepare suitable...
High-throughput liquid chromatography/mass spectrometry (LC/MS) is an increasing topic in analytical chemistry. Especially the idle time of a mass spectrometer should be reduced for efficient and cost-saving use. Therefore, fast-switching dual ion source was developed, which uses most important ionization techniques at atmospheric pressure, electrospray (ESI) pressure chemical (APCI), with one or more LC systems.The performance developed shown by infusion experiments chromatographic analyses...
Abstract Cystic fibrosis (CF) is an autosomal recessive inherited disease which leads to a production of thickened mucus in the airways. These conditions are conducive poly-microbial infections, like chronic lung infection, Pseudomonas aeruginosa ( P. ) major pathogenic bacterium colonizing CF lungs at end lifetime patients. This vitro study uses biofilm model under partly cystic conditions, with sampling volatile extracellular metabolites. The gas was done thin-film microextraction (TFME)...
Rationale An argon inverse low‐temperature plasma (iLTP) ionization source for liquid chromatography/tandem mass spectrometry was developed. The iLTP is constructed from simple chromatographic supply materials and implemented into an atmospheric pressure chemical (APCI) replacing the APCI discharge needle electrode. newly developed ion coupled to ultra‐high‐performance chromatography (UHPLC) system. Methods characterized by optical emission spectroscopy. soft of selected standards also...
Abstract The mechanical bond is emerging as a novel design element in catalyst development. Here, we report series of 1,1’‐binaphthyl‐2,2’‐diol (BINOL) based catalysts which the number interlocked macrocycles varied. Unsurprisingly, have profound steric influence on catalytic performance these molecules. However, enantioselective transformations examined, are detrimental to stereoselectivity whereas lactide polymerization, they increase molecular weight polymeric product.
An effective nebulization and evaporation of a liquid sample, like in chromatography, mass spectrometry (LC-MS) couplings, is an essential requirement for the ionization analyte molecules gas phase by, example, atmospheric pressure chemical (APCI) or novel low temperature plasma (LTP)-based ion source. These LTP-based sources have recently gained interest field sources, as they can cover wide range polarity molecular mass. They be used combination with separation techniques chromatography...
A closed atmospheric pressure chemical ionization (APCI) ion source as interface between a gas chromatograph (GC) and triple quadrupole mass spectrometer (QqQ-MS) was developed. The influence of different conditions, such humidity, make-up flow, the position GC column, were investigated determined main factors to increase sensitivity repeatability system. For performance test under real new APCI used for determination plant protection products in commercially available coffee beans from...
In this paper we demonstrate that the choice of an appropriate non-polar modifier which can provide sufficient chemical interactions with target analytes may lead to improvement selectivity and sensitivity differential ion mobility spectrometric (DMS) methods.
The monitoring of phthalate esters (PAEs) is challenging due to background contamination as well the low selectivity observed when analyzing them by gas chromatography coupled mass spectrometry (GC-MS) using electron ionization (EI). In this sense, alternative and soft techniques could help enhance performance analytical determinations PAEs in food samples. work, use a novel technique tube plasma (TPI) has been explored sensitivity determination drinking water samples with GC-MS. First,...