Zhongxue Wu

ORCID: 0000-0003-4261-2761
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About
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Research Areas
  • Intracranial Aneurysms: Treatment and Complications
  • Vascular Malformations Diagnosis and Treatment
  • Cerebrovascular and Carotid Artery Diseases
  • Moyamoya disease diagnosis and treatment
  • Intracerebral and Subarachnoid Hemorrhage Research
  • Traumatic Brain Injury and Neurovascular Disturbances
  • Neurosurgical Procedures and Complications
  • Cerebral Venous Sinus Thrombosis
  • Spinal Fractures and Fixation Techniques
  • Meningioma and schwannoma management
  • Trigeminal Neuralgia and Treatments
  • Aortic aneurysm repair treatments
  • Acute Ischemic Stroke Management
  • Aortic Disease and Treatment Approaches
  • Inflammatory Biomarkers in Disease Prognosis
  • Medical Imaging and Analysis
  • Cerebrospinal fluid and hydrocephalus
  • Extracellular vesicles in disease
  • Retinal and Optic Conditions
  • Pelvic and Acetabular Injuries
  • Autophagy in Disease and Therapy
  • MicroRNA in disease regulation
  • Migraine and Headache Studies
  • Stroke Rehabilitation and Recovery
  • Heme Oxygenase-1 and Carbon Monoxide

Beijing Institute of Neurosurgery
2014-2023

Capital Medical University
2014-2023

Fujian Medical University
2023

Beijing Tian Tan Hospital
2008-2022

National Clinical Research Center for Digestive Diseases
2021

National Clinical Research
2021

Beijing Hospital
2020

Beijing Tsinghua Chang Gung Hospital
2019

Tsinghua University
2019

Capital University
2013

<b>BACKGROUND AND PURPOSE:</b> An increasing number of intracranial dural arteriovenous fistulas (DAVFs) are amenable to endovascular treatment with Onyx. However, reports on complications caused by this technique have been limited. We present the initial Beijing Tiantan Hospital experience adverse events related transarterial Onyx embolization for DAVFs. <b>MATERIALS METHODS:</b> Between September 2005 and February 2008, a total 40 patients DAVFs were treated at our institute Onyx-18. There...

10.3174/ajnr.a1419 article EN cc-by American Journal of Neuroradiology 2009-01-08

This paper reports the incidence of trigeminocardiac reflex (TCR) in endovascular treatment dural arteriovenous fistulas (DAVFs) with Onyx. The consecutive case histories 45 patients DAVFs, treated Onyx transarterially and transvenously, from February 2005 to 2008 at Beijing Tiantan Hospital, China, were retrospectively reviewed. time period was limited as anesthetic intravascular procedure performed under same standardized protocol by team. TCR rate subsequently calculated. Of patients,...

10.1177/159101991001600107 article EN Interventional Neuroradiology 2010-03-01

To estimate for hemorrhage risk of partially endovascularly embolized brain arteriovenous malformation (BAVM).We retrospectively reviewed 147 consecutive patients with BAVM-treated mainly endovascular N-butyl cyanoacrylate (NBCA) and ONYX embolization. In Kaplan-Meier survival analysis, the index date was dated initial embolization; cases were censored at time subsequent intracranial (ICH), or loss to follow-up, multivariate proportional-hazards regression models included age presentation...

10.1179/1743132812y.0000000044 article EN Neurological Research 2012-06-05

This study analyzed the rupture risk of intracranial aneurysms (IAs) according to aneurysm characteristics by comparing differences between two in different locations within same patient. We utilized this self-controlled model exclude potential interference from all demographic factors related IA rupture. A total 103 patients were diagnosed with IAs January 2011 and April 2015 enrolled study. All had IAs. One (the case) was ruptured, other control) unruptured. Aneurysm characteristics,...

10.1371/journal.pone.0142330 article EN cc-by PLoS ONE 2015-11-05

Background and Purpose: We aimed to investigate the effect of smoking on risk intracranial aneurysm (IA) rupture (IAR), specifically relationship between number cigarettes smoked per day (CPD) or index IAR. Methods: performed a single-center case-control study consecutive patients evaluated treated for IA at our institution from June 2015-July 2016.Cases were with ruptured IA. Two age- sex-matched controls an unruptured included case. Conditional logistic regression models used assess both...

10.3389/fneur.2018.00380 article EN cc-by Frontiers in Neurology 2018-05-31

Use of the Onyx liquid embolic system has become an option for treating dural arteriovenous fistulas (DAVFs) because its advantageous nonadhesive and cohesive properties. However, complication rates associated with use this have not been reported. The authors present their initial experience risks related to transarterial embolization using system.Between February 2005 2007, 31 patients DAVFs were treated at Beijing Tiantan Hospital. Transarterial Onyx-18 was performed as a preoperative...

10.3171/jns.2008.109.12.1083 article EN Journal of neurosurgery 2008-11-26

Surgical treatment of VA-PICA dissecting aneurysms is difficult and complication LCNP common. These lesions can be approached easily with endovascular technique, but complete obliteration only achieved in a small number cases. Our aim was to report the clinical outcomes treated by embolization.Between 2001 2007, authors 22 consecutive patients (15 men 7 women; ranging age from 12 59 years; mean age, 43 years) aneurysms. Diagnosis aneurysm based on clinical, MR imaging, cerebral angiography...

10.3174/ajnr.a2087 article EN cc-by American Journal of Neuroradiology 2010-04-15

&lt;i&gt;Background:&lt;/i&gt; The biological mechanisms by which cerebral aneurysms emerge, enlarge and rupture are not totally understood. In the present study, we analyzed genome-wide gene expression profile in human intracranial using cDNA microarrays. &lt;i&gt;Methods:&lt;/i&gt; Affymetrix HU133 Plus 2.0 microarrays were used to compare levels between aneurismal samples normal blood vessels. Raw data evaluated GeneSpring software version 9.05. Differentially expressed genes further...

10.1159/000236911 article EN European Neurology 2009-01-01

<b>BACKGROUND AND PURPOSE:</b>Brain arteriovenous fistulas (BAVFs) are dangerous lesions with significant risks for hemorrhage and re-hemorrhage; thus, the management of BAVFs is an important subject. Flow disconnection can be accomplished by surgical or endovascular techniques. We reviewed experience in our treatment patients BAVFs. <b>MATERIALS METHODS:</b>From March 2006 to 2008, a total 9 consecutive nontraumatic were treated at Beijing Tiantan Hospital. Dural Galen aneurysmal...

10.3174/ajnr.a1436 article EN cc-by American Journal of Neuroradiology 2009-01-15

Background and Purpose— Procedure-related neurological complications are common after endovascular treatment of unruptured intracranial aneurysms. We aimed to develop a score quantify individual patient risk. Methods— retrospectively analyzed consecutive patients who underwent for aneurysms between January 2012 September 2015. After excluding those lost follow-up with fusiform aneurysms, included were randomly divided into derivation group (60%) validation (40%). A complication was defined...

10.1161/strokeaha.115.012097 article EN cc-by-nc-nd Stroke 2016-02-12

Background: Pipeline embolization device (PED) is becoming increasingly common in therapeutic practice. In idealized model studies, treatment effectiveness may vary with different stent sizes the same vasculature. The true effect of size selection clinical setting remains unknown, however. Objective: To determine setting. Design: It a retrospective review. Methods: A review was conducted on consecutive patients aneurysms treated PED at our institution. primary exposures were difference...

10.1177/17562864231151475 article EN cc-by-nc Therapeutic Advances in Neurological Disorders 2023-01-01

<b>SUMMARY:</b> We report a case of immediate reproducible and reflexive response asystole upon stimulation Onyx injection during embolization tentorial dural arteriovenous fistula in 53-year-old man. Upon recognition the relationship between increased vagal tone, patient was given anticholinergic an effort to block cholinergic hyperactivity. After atropine given, no further dysrhythmias occurred.

10.3174/ajnr.a0675 article EN cc-by American Journal of Neuroradiology 2007-09-20

We report our experience in treating patients with seizures associated brain arteriovenous malformations (AVM) without a clinical history of intracranial hemorrhage. Between 2001 and 2003, the neurovascular unit at Beijing Tiantan Hospital treated 109 AVM endovascularly. Thirty (27.5%) experienced before treatment. studied following factors: sex, age, size, location, seizure type, duration history, endovascular treatment obliteration. Clinical follow-up was via telephone interview. disorders...

10.1177/159101991001600105 article EN Interventional Neuroradiology 2010-03-01
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