A5058110513- biodegradable polymer synthesis and properties
- Synthesis and biological activity
- Carbon dioxide utilization in catalysis
- Synthesis and Characterization of Heterocyclic Compounds
- Electrospun Nanofibers in Biomedical Applications
- Advanced Polymer Synthesis and Characterization
- Nanoparticle-Based Drug Delivery
- Graphene and Nanomaterials Applications
- Synthesis of Tetrazole Derivatives
- Wound Healing and Treatments
- Polymer Science and PVC
- Polymer crystallization and properties
- Polymer Nanocomposites and Properties
- Natural Fiber Reinforced Composites
- Polymer Surface Interaction Studies
- Intraperitoneal and Appendiceal Malignancies
- Advanced Sensor and Energy Harvesting Materials
- Chemistry Education and Research
- Chemical synthesis and pharmacological studies
- Adsorption, diffusion, and thermodynamic properties of materials
- Adsorption and biosorption for pollutant removal
- Silk-based biomaterials and applications
- Railway Systems and Materials Science
- Advanced Battery Materials and Technologies
- Thermal and Kinetic Analysis
National Chemical Laboratory
2012-2024
Academy of Scientific and Innovative Research
2017-2024
Berhampur University
2017-2024
Council of Scientific and Industrial Research
2022
Indian Institute of Technology Kharagpur
2012
Sanskriti Samvardhan Mandal
2012
Savitribai Phule Pune University
2012
GTx (United States)
2010
Sambalpur University
1990-1991
Abstract: Ciprofloxacin was conjugated with polylactide (PLA) via the secondary amine group of piperazine ring using PLA and 7-(4-(2-Chloroacetyl) piperazin-1-yl)-1-cyclopropyl-6-fluoro-1, 4-dihydro-4-oxoquinoline-3-carboxylic acid. Zinc prolinate, a biocompatible catalyst synthesized, characterized, used in opening polymerization L-lactide. Five different kinds OH-terminated poly(L-lactide) (two-, three-, four-, six-arm, star-shaped) homopolymers were synthesized by L-lactide presence...
Biomaterials used as blood-contacting material must be hemocompatible and exhibit lower thrombotic potential while maintaining hemostasis angiogenesis. With the aim of developing thromboresistant, nanofibrous scaffolds, polyurethane/polyethylene glycol scaffolds incorporated with 1, 5, 10 wt% Clopidogrel were fabricated evaluated for their physiochemical properties, biocompatibility, hemocompatibility, antithrombotic potential. The results physicochemical characterization revealed...
Well-defined six-arm star-branched bio-degradable block copolymers of l-lactide and ε-caprolactone were prepared using controlled ring-opening polymerization a sequential monomer addition method dipentaerythritol as the initiator core organocatalysts at low temperatures in solution. Sequence enchainment was changed by reversing order giving, either, crystalline PLA or an amorphous PCL outer segment. poly(ε-caprolactone-b-l-lactide, 6s-PCL-b-PLA) obtained with range segment molecular weights....
Solid state 13C CP/MAS studies of poly(vinyl chloride) (PVC)−bis(2-ethylhexyl) phthalate (DOP) have been carried out to elucidate the dynamics polymer−plasticizer interaction at molecular level. NMR spectra, spin−lattice relaxation time T1(C) and spin−spin T2(C) were obtained for various PVC−DOP samples. Line widths 〉CHCl show a sharp increase due strong hydrogen-bonding between 〉CO (ester) group DOP PVC with concentrations DOP. The also confirms presence hydrogen bonding. less mobile...
Green synthesis of mPEG–PLGA and nanoformulation for delivery irinotecan to colon cancer.
Abstract The synthesis of low‐molecular‐weight (weight‐average molecular weight < 45,000 g/mol) lactic acid polymers through the dehydropolycondensation L ‐lactic was investigated. Polymerizations were carried out in solution with solvents (xylene, mesitylene, and decalin), without a solvent using different Lewis catalysts (tetraphenyl tin tetra‐ n ‐butyldichlorodistannoxane), at three polymerization temperatures (143, 165, 190 °C). products characterized differential scanning...
Poly(l-lactide) (PLLA) was synthesized from l-lactide in the presence of a zinc salen complex. Ofloxacin (OFLX)-loaded PLLA nanofibrous mats were fabricated by electrospinning using dichloromethane/dimethyl sulfoxide (4:1 v/v) solutions containing different amounts OFLX (1, 3, 5, and 10 w/w%). The morphology diameter studied scanning electron microscopy (SEM). internal nanofibers examined transmission (TEM). Miscibility between confirmed attenuated total reflection-Fourier transform infrared...
A poly(d,l-lactide-co-glycolide) (PLGA) copolymer was synthesized using the ring-opening polymerization of d,l-lactide and glycolide monomers in presence zinc proline complex bulk through green route well characterized attenuated total reflectance–Fourier transform infrared, 1H 13C nuclear magnetic resonance, gel permeation chromatography, differential scanning calorimetry, X-ray diffraction, matrix-assisted laser desorption/ionization time-of-flight, etc. Furthermore, PLGA-conjugated biotin...
Abstract Poly(lactide‐co‐glycolide) (PLGA) copolymers were synthesized by ring opening polymerization in presence of zinc proline and stannous octoate bulk through green route designated as PLGA‐1 PLGA‐2 respectively. These characterized using NMR, SEC, DSC, X‐ray MALDI‐TOF analysis. For the first time, low molecular weight PLGA (~11,000 Da) was mainly targeted to explore acute oral toxicity L‐proline octoate. The haemolysis cell viability assay carried out for in‐vitro cytotoxicity...
Poly(lactide-
A biocompatible zinc (II) complex based on a tetradentate N,N,O,O-type salen ligand was synthesized, characterized and used for the solvent-free ring-opening polymerization (ROP) of L-lactide in bulk at 180 °C to prepare high molecular weight poly(L-lactide) (Mn: 82,600 Da; Mw: 140,000 PDI: 1.70). Poly(L-lactide) (PLLA) using FTIR, 1H NMR, 13C GPC, TGA, DSC, WAXD, MALDI-ToF. Kinetic measurement carried out first-order behavior monomer observed. The kapp found as 6 ± 0.001 × 10−4 s−1....
In recent year, biocompatible, biodegradable materials (linear polylactic acid-based urethanes) in the solid and/or liquid form have attracted tremendous attention biomedical application particularly stent coating. Low molecular weight poly (lactic acid) s (PLA), having narrow distribution was by dehydropolycondensation method using tetraphenyltin as a catalyst. Hydroxyl terminated linear acid prepared reacting PLA with aliphatic diol compounds. The hydroxyl end groups were determined 31P...
Abstract A novel biodegradable polymer poly(aleuritic acid) (PAA) ( M̄w 120,000) was prepared from aleuritic acid, which obtained renewable resources (Lac) by using tin catalyst. Aleuritic acid (AL) protected at 9, 10 position dimethoxy propane. The AL (Pro.AL) further polymerized to obtain linear polyaleuritic (PAL) dehydropolycondensation. Effects of various kinetic and thermodynamic parameters were studied. After polymerization, the deprotection PAL carried out. synthesized PAA...
Correlation between hydrogen-bonding self-association and sequence distribution in poly(vinyl acetate-co-vinyl alcohol) copolymers (ACA) with different degrees of basic hydrolysis distributions has been studied by thermal analysis NMR spectroscopy. 13C spectroscopy also used to elucidate the blocky nature, branching, tacticity copolymers. Thermal analytical studies indicate that hydrogen bonding block alcohol vinyl acetate strongly depend on wherein hydroxyl–hydroxyl is preferred. © 1999...
Synthesis of industrially most valuable and low-cost materials for repeated CO<sub>2</sub> adsorption at low temperatures desorption without energy.