Cole Knuese

ORCID: 0000-0003-4274-0923
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About
Contact & Profiles
Research Areas
  • Viral Infections and Vectors
  • Viral Infections and Outbreaks Research
  • Mosquito-borne diseases and control
  • Plant Virus Research Studies
  • Vector-Borne Animal Diseases

University of Wisconsin–Madison
2023-2025

Despite the success of widely used attenuated yellow fever (YF) vaccine, its global supply remains a substantial barrier to implementing vaccination campaigns in endemic regions and combating emerging epidemics. In A129 mice rhesus macaques, we evaluated immunogenicity protective activity messenger RNA (mRNA) vaccine candidates encapsulated lipid nanoparticles, expressing pre-membrane envelope proteins or non-structural protein 1 YF virus. Vaccine constructs induced humoral cell-mediated...

10.1038/s41541-023-00629-7 article EN cc-by npj Vaccines 2023-03-04
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