A5072790670- Mosquito-borne diseases and control
- Power Quality and Harmonics
- Viral Infections and Vectors
- Vector-Borne Animal Diseases
- Animal Disease Management and Epidemiology
- Viral Infections and Outbreaks Research
- Insect symbiosis and bacterial influences
- Viral gastroenteritis research and epidemiology
- Alzheimer's disease research and treatments
- Agricultural and Food Production Studies
- Supramolecular Self-Assembly in Materials
- Genetic diversity and population structure
- Spanish History and Politics
- Media and Digital Communication
- Public Health and Social Inequalities
- Public Health and Environmental Issues
- Virology and Viral Diseases
- Poxvirus research and outbreaks
- Genetic and phenotypic traits in livestock
- Power Transformer Diagnostics and Insulation
- Energy Load and Power Forecasting
- T-cell and Retrovirus Studies
- Phytochemicals and Medicinal Plants
- Historical and socio-economic studies of Spain and related regions
- vaccines and immunoinformatics approaches
University of Wisconsin–Madison
2017-2023
Universidad de Antioquia
2005-2020
Universidad Pontificia Bolivariana
2005
Universidad Cooperativa de Colombia
2001
Colombia is a country with great geographic heterogeneity and marked regional differences in pre-Columbian native population density the extent of past African European immigration. As result, has one most diverse populations Latin America. Here we evaluated ancestry over 1,700 individuals from 24 Colombian using biparental (autosomal X-Chromosome), maternal (mtDNA), paternal (Y-chromosome) markers. Autosomal varies markedly both within between regions, confirming genetic diversity...
Abstract White-nose syndrome (WNS) caused by the fungus, Pseudogymnoascus destructans ( Pd ) has killed millions of North American hibernating bats. Currently, methods to prevent disease are limited. We conducted two trials assess potential WNS vaccine candidates in wild-caught Myotis lucifugus . In a pilot study, we immunized bats with one four treatments or phosphate-buffered saline (PBS) as control and challenged them upon transfer into hibernation chambers. Bats vaccine-treated group,...
Zika virus (ZIKV), a mosquito-borne flavivirus, has recently triggered global concern due to severe health complications. In 2015, large ZIKV outbreak occurred in the Americas and established link between microcephaly newborn babies, spontaneous abortion, persistent viremia, Guillain-Barré syndrome. While antivirals are being developed prevention strategies focus on vector control, safe effective vaccine remains unavailable. Messenger RNA (mRNA) technology arisen as flexible, simplified,...
Despite the success of widely used attenuated yellow fever (YF) vaccine, its global supply remains a substantial barrier to implementing vaccination campaigns in endemic regions and combating emerging epidemics. In A129 mice rhesus macaques, we evaluated immunogenicity protective activity messenger RNA (mRNA) vaccine candidates encapsulated lipid nanoparticles, expressing pre-membrane envelope proteins or non-structural protein 1 YF virus. Vaccine constructs induced humoral cell-mediated...
African swine fever virus (ASFV) causes a highly contagious hemorrhagic disease that affects domestic pig and Eurasian wild boar populations. To date, no safe efficacious treatment or vaccine against ASF is available. Nevertheless, there are several reports of protection elicited by experimental vaccines based on live attenuated ASFV some levels reduced viremia in other approaches such as DNA, adenovirus, baculovirus, vaccinia-based vaccines. Current subunit research focuses mainly...
Nipah virus (NiV), an emerging zoonotic pathogen in Southeast Asia, is transmitted from Pteropus species of fruit bats to a wide range species, including humans, pigs, horses, dogs, and cats. NiV has killed millions animals caused highly fatal human outbreaks since no vaccine commercially available. This study characterized the immunogenicity safety poxvirus-based vaccines that can be used humans responsible for transmission. Mice were vaccinated with modified vaccinia Ankara (MVA) raccoon...
Dengue viruses (DENV) have become the most important arthropod-borne viruses, causing dengue and severe fever in at least 50-100 million cases each year, mainly tropical subtropical countries. During recent years, advances molecular biology concerning life cycle of these allowed manipulation generation recombinant replicons with multiple applications, viral screening antiviral compounds. In present study, we describe construction an enhanced green fluorescent protein-bearing DENV replicon...
Rabies is an ancient disease that responsible for approximately 59,000 human deaths annually. Bats (Order Chiroptera) are thought to be the original hosts of rabies virus (RABV) and currently account most cases in wildlife Americas. Vaccination being used manage other reservoirs like fox raccoon, but no vaccine available bats. We previously developed a recombinant raccoonpox (RCN) candidate expressing mosaic glycoprotein (MoG) gene protected mice big brown bats when challenged with RABV. In...
Se evaluo la cobertura de afiliacion al regimen subsidiado y se determino accesibilidad a los servicios salud en poblacion mas pobre vulnerable del municipio Medellin. Es un estudio evaluativo-descriptivo tipo transversal mediante aplicacion una entrevista semiestructurada muestra representativa 1,200 afiliados seleccionados aleatoriamente con afijacion proporcional las zonas, comunas corregimientos Incluyo el analisis 223,459 registros extraidos bases datos para obtencion indicadores...
This paper describes a synthetic (because it homologues and superpose various phenomena) systemic (oriented to system's performance) model for power quality (PQ) assessment. The proposes an n dimensional electromagnetic "incompatibility" (EMiC) vector, where each vector's component evaluates PQ phenomena that's independent from the others (in order assure orthogonality between them) must be conveniently normalized. By use of computer simulation is shown that voltage fluctuation's...
Abstract African swine fever virus (ASFV) causes a highly contagious hemorrhagic disease that affects domestic pig and Eurasian wild boar populations. To date, no safe efficacious treatment or vaccine against ASF is available. Nevertheless, there are several reports of protection elicited by experimental vaccines based on live attenuated ASFV some levels reduced viremia in other approaches such as DNA, adenovirus, baculovirus, vaccinia-based vaccines. Current subunit research focuses mainly...